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Alleviating symptoms of neurodegenerative disorders by astrocyte-specific overexpression of TMEM164 in mice

Authors: Liansheng Zhang, Zhiheng Jia, Qiang Wu, Tao Bai, Bo Wang, Xinde Hu, Tianwen Li, Xingyu Liu, Jiqiang Fu, Yuelei Chen, Xiaoyan Ding, Zhen Liu, Zhengzheng Xu, Haibo Zhou

Journal: Nat Metab

PubMed ID: 37679556

Doi: 10.1038/s42255-023-00887-8

Products & Services: Protein and Antibody Isolation

The Orf9b protein of SARS-CoV-2 modulates mitochondrial protein biogenesis

Authors: Svenja Lenhard, Sarah Gerlich, Azkia Khan, Saskia Rödl, Jan-Eric Bökenkamp, Esra Peker, Christine Zarges, Janina Faust, Zuzana Storchova, Markus Räschle, Jan Riemer, Johannes M Herrmann

Journal: J Cell Biol

PubMed ID: 37682539

Doi: 10.1083/jcb.202303002

Products & Services: Recombinant Proteins

Robust Strategy for Hit-to-Lead Discovery: NMR for SAR

Authors: Sacha T Larda, Yann Ayotte, Maria M Denk, Paul Coote, Gregory Heffron, David Bendahan, Fatma Shahout, Nicolas Girard, Mustapha Iddir, Patricia Bouchard, Francois Bilodeau, Simon Woo, Luc J Farmer, Steven R LaPlante

Journal: J Med Chem

PubMed ID: 37732695

Doi: 10.1021/acs.jmedchem.3c00656

Products & Services: Plasmid DNA Preparation

Recombinant Lactococcus lactis Expressing Human LL-37 Prevents Deaths from Viral Infections in Piglets and Chicken

Authors: Hanlin Zhang, Meng Dong, Huihui Xu, Hongyue Li, Aihua Zheng, Gang Sun, Wanzhu Jin

Journal: Probiotics Antimicrob Proteins

PubMed ID: 37743432

Doi: 10.1007/s12602-023-10155-6

Products & Services: Molecular Biology Reagents

Preclinical Development and Characterization of Novel Adeno-Associated Viral Vectors for the Treatment of Lipoprotein Lipase Deficiency

Authors: Neel Mehta, Rénald Gilbert, Parminder S Chahal, Maria J Moreno, Nasha Nassoury, Nathalie Coulombe, Viktoria Lytvyn, Mario Mercier, Dorothy Fatehi, Wendy Lin, Emily M Harvey, Lin-Hua Zhang, Nazila Nazemi-Moghaddam, Seyyed Mehdy Elahi, Colin J D Ross, Danica B Stanimirovic, Michael R Hayden

Journal: Hum Gene Ther

PubMed ID: 37597209

Doi: 10.1089/hum.2023.075

Products & Services: Protein and Antibody Isolation

designed Hsp70 activator dissolves intracellular condensates

Authors: Jason Z Zhang, Nathan Greenwood, Jason Hernandez, Josh T Cuperus, Buwei Huang, Bryan D Ryder, Christine Queitsch, Jason E Gestwicki, David Baker

Journal: biorxiv

PubMed ID: 37781598

Doi: 10.1101/2023.09.18.558356

Products & Services: Protein and Antibody Isolation

High-volume hybridoma sequencing on the NeuroMabSeq platform enables efficient generation of recombinant monoclonal antibodies and scFvs for neuroscience research

Authors: Keith G Mitchell, Belvin Gong, Samuel S Hunter, Diana Burkart-Waco, Clara E Gavira-O'Neill, Kayla M Templeton, Madeline E Goethel, Malgorzata Bzymek, Leah M MacNiven, Karl D Murray, Matthew L Settles, Lutz Froenicke, James S Trimmer

Journal: Sci Rep

PubMed ID: 37758930

Doi: 10.1038/s41598-023-43233-4

Products & Services: Protein and Antibody Isolation

Epidermal growth factor receptor regulates lineage plasticity driving transformation to small cell lung cancer

Authors: Meng Jing, Xia He, Cheng Zhi Cai, Qi Zhi Ma, Kai Li, Ben Xia Zhang, Yuan Yin, Ming Song Shi, Yong Sheng Wang

Journal: Biochem Biophys Res Commun

PubMed ID: 37783120

Doi: 10.1016/j.bbrc.2023.09.047

Products & Services: Protein and Antibody Isolation

Antigen-specific CD4 T cells exhibit distinct transcriptional phenotypes in the lymph node and blood following vaccination in humans

Authors: Philip Mudd, Nicholas Borcherding, Wooseob Kim, Michael Quinn, Fangjie Han, Julian Zhou, Alexandria Sturtz, Aaron Schmitz, Tingting Lei, Stefan Schattgen, Michael Klebert, Teresa Suessen, William Middleton, Charles Goss, Chang Liu, Jeremy Crawford, Paul Thomas, Sharlene Teefey, Rachel Presti, Jane O'Halloran, Jackson Turner, Ali Ellebedy

Journal: Res Sq

PubMed ID: 37790414

Doi: 10.21203/rs.3.rs-3304466/v1

Products & Services: Protein and Antibody Isolation

HCMV UL8 interaction with β-catenin and DVL2 regulates viral reactivation in CD34 hematopoietic progenitor cells

Authors: Aaron Dirck, Nicole L Diggins, Lindsey B Crawford, Wilma D Perez, Christopher J Parkins, Hillary H Struthers, Rebekah Turner, Andrew H Pham, Jennifer Mitchell, Courtney R Papen, Daniel Malouli, Meaghan H Hancock, Patrizia Caposio

Journal: J Virol

PubMed ID: 37772824

Doi: 10.1128/jvi.01241-23

Products & Services: Protein and Antibody Isolation