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Modified mRNA Formulation and Stability for Cardiac and Skeletal Muscle Delivery

Authors: Magdalena M Żak, Keerat Kaur, Jimeen Yoo, Ann Anu Kurian, Matthew Adjmi, Gayatri Mainkar, Seonghun Yoon, Lior Zangi

Journal: Pharmaceutics

PubMed ID: 37765147

Doi: 10.3390/pharmaceutics15092176

Products & Services: Molecular Biology Reagents

Preclinical evaluation of manufacturable SARS-CoV-2 spike virus-like particles produced in Chinese Hamster Ovary cells

Authors: Sergio P Alpuche-Lazcano, Matthew Stuible, Bassel Akache, Anh Tran, John Kelly, Sabahudin Hrapovic, Anna Robotham, Arsalan Haqqani, Alexandra Star, Tyler M Renner, Julie Blouin, Jean-Sébastien Maltais, Brian Cass, Kai Cui, Jae-Young Cho, Xinyu Wang, Daria Zoubchenok, Renu Dudani, Diana Duque, Michael J McCluskie, Yves Durocher

Journal: Commun Med (Lond)

PubMed ID: 37612423

Doi: 10.1038/s43856-023-00340-7

Products & Services: Protein and Antibody Isolation

Enhancement of Neutralization Responses through Sequential Immunization of Stable Env Trimers Based on Consensus Sequences from Select Time Points by Mimicking Natural Infection

Authors: Mingming Wan, Xiao Yang, Jie Sun, Elena E Giorgi, Xue Ding, Yan Zhou, Yong Zhang, Weiheng Su, Chunlai Jiang, Yaming Shan, Feng Gao

Journal: Int J Mol Sci

PubMed ID: 37628824

Doi: 10.3390/ijms241612642

Products & Services: Gene Synthesis

Structure and design of Langya virus glycoprotein antigens

Authors: Zhaoqian Wang, Matthew McCallum, Lianying Yan, William Sharkey, Young-Jun Park, Ha V Dang, Moushimi Amaya, Ashley Person, Christopher C Broder, David Veesler

Journal: biorxiv

PubMed ID: 37645760

Doi: 10.1101/2023.08.20.554025

Products & Services: ORF cDNA Clones/MolecularCloud

Structural mechanism of synergistic targeting of the nucleosome by PU1 and C/EBPα

Authors: Tengfei Lian, Ruifang Guan, Bing-Rui Zhou, Yawen Bai

Journal: biorxiv

PubMed ID: 37790476

Doi: 10.1101/2023.08.25.554718

Products & Services: Gene Synthesis

High resolution cryo-EM and crystallographic snapshots of the actinobacterial two-in-one 2-oxoglutarate dehydrogenase

Authors: Lu Yang, Tristan Wagner, Ariel Mechaly, Alexandra Boyko, Eduardo M Bruch, Daniela Megrian, Francesca Gubellini, Pedro M Alzari, Marco Bellinzoni

Journal: Nat Commun

PubMed ID: 37563123

Doi: 10.1038/s41467-023-40253-6

Products & Services: Protein and Antibody Isolation

Toward non-factor therapy in hemophilia: an antithrombin insensitive Gla-domainless factor Xa as tissue factor pathway inhibitor bait

Authors: Marie-Claire Dagher, Atanur Ersayin, Landry Seyve, Mathieu Castellan, Cyril Moreau, Luc Choisnard, Nicole Thielens, Raphaël Marlu, Benoît Polack, Aline Thomas

Journal: Res Pract Thromb Haemost

PubMed ID: 37841511

Doi: 10.1016/j.rpth.2023.102175

Products & Services: Combinatorial Mutant library

Immobilization of α-transglucosidase on silica-coated magnetic nanoparticles and its application for production of isomaltooligosaccharide from the potato peel

Authors: Rohit Maurya, Usman Ali, Sunaina Kaul, Raja Bhaiyya, Ravindra Pal Singh, Koushik Mazumder

Journal: Sci Rep

PubMed ID: 37543692

Doi: 10.1038/s41598-023-38266-8

Products & Services: Molecular Biology Reagents

CircMIB2 therapy can effectively treat pathogenic infection by encoding a novel protein

Authors: Weiwei Zheng, Linchao Wang, Shang Geng, Liyuan Yang, Xing Lv, Shiying Xin, Tianjun Xu

Journal: Cell Death Dis

PubMed ID: 37652905

Doi: 10.1038/s41419-023-06105-3

Products & Services: Custom RNAi Services

Precision Genome Engineering in Based on a Broad-Host-Range Vector and CRISPR-Cas9 Technology

Authors: Alex Gussak, Maria Laura Ferrando, Mels Schrama, Peter van Baarlen, Jerry Mark Wells

Journal: ACS Synth Biol

PubMed ID: 37602730

Doi: 10.1021/acssynbio.3c00110

Products & Services: Peptide Synthesis