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TNP Analogues Inhibit the Virulence Promoting IP3-4 Kinase Arg1 in the Fungal Pathogen Cryptococcus neoformans

Authors: Desmarini Desmarini, Daniel Truong, Lorna Wilkinson-White, Chandrika Desphande, Mario Torrado, Joel P Mackay, Jacqueline M Matthews, Tania C Sorrell, Sophie Lev, Philip E Thompson, Julianne Teresa Djordjevic

Journal: Biomolecules

PubMed ID: 36291735

Doi: 10.3390/biom12101526

Products & Services: Plasmid DNA Preparation

Observation of conformational changes that underlie the catalytic cycle of Xrn2

Authors: Jan H Overbeck, David Stelzig, Anna-Lisa Fuchs, Jan Philip Wurm, Remco Sprangers

Journal: Nature Chemical Biology

PubMed ID: 36008487

Doi: 10.1038/s41589-022-01111-6

Products & Services: Codon Optimization Gene Synthesis

Functional EGF domain of the human neuregulin 1α produced in Escherichia coli with accurate disulfide bonds

Authors: Arthur Schveitzer Ferreira, Amanda Lopacinski, Michel Batista, Priscila Mazzocchi Hiraiwa, Natalia Fernanda Bueno, Beatriz Gomes Guimarães, Nilson I T Zanchin

Journal: Mol Biol Rep

PubMed ID: 36198848

Doi: 10.1007/s11033-022-07956-3

Products & Services: Plasmid DNA Preparation

Mechanistic insights into cancer drug resistance through optogenetic PI3K signaling hyperactivation

Authors: Yoshibumi Ueda, Yuri Miura, Nario Tomishige, Naotoshi Sugimoto, Megumi Murase, Genki Kawamura, Norihiko Sasaki, Toshiyuki Ishiwata, Takeaki Ozawa

Journal: Cell Chem Biol

PubMed ID: 36288730

Doi: 10.1016/j.chembiol.2022.10.002

Products & Services: Mammalian Expression

The Antimicrobial Peptide LJ-hep2 from Exerting Activities against Multiple Pathogenic Bacteria and Immune Protection In Vivo

Authors: Ruihao Gong, Zhe An, Weibin Zhang, Fangyi Chen, Ke-Jian Wang

Journal: Mar Drugs

PubMed ID: 36286474

Doi: 10.3390/md20100651

Products & Services: Custom Vector Construction

Inhibition of intermittent calcium-activated potassium channel (SK4) attenuates Ang II-induced hypertrophy of human-induced stem cell-derived cardiomyocytes via targeting Ras-Raf-MEK1/2-ERK1/2 and CN-NFAT signaling pathways

Authors: Hongyi Zhao, Xi Wang, Yanhong Tang, Qingyan Zhao, Congxin Huang

Journal: Cell Biol Int

PubMed ID: 36273427

Doi: 10.1002/cbin.11948

Products & Services: Molecular Biology Reagents

Engineering Self-Assembled Endolysin Nanoparticles against Antibiotic-Resistant Bacteria

Authors: Christian K O Dzuvor, Bhuvana K Shanbhag, Tayyaba Younas, Hsin-Hui Shen, Victoria S Haritos, Lizhong He

Journal: ACS Appl Bio Mater

PubMed ID: 36194892

Doi: 10.1021/acsabm.2c00741

Products & Services: Protein and Antibody Isolation

Differential expression and roles of Huntingtin and Huntingtin-associated protein 1 in the mouse and primate brains

Authors: Xingxing Chen, Yize Sun, Laiqiang Chen, Xiu-Sheng Chen, Mingtian Pan, Yiran Zhang, Qi Wang, Weili Yang, Peng Yin, Dajian He, Xiangyu Guo, Su Yang, Yan Zeng, Sen Yan, Xiao-Jiang Li, Shihua Li

Journal: Cell Mol Life Sci

PubMed ID: 36251080

Doi: 10.1007/s00018-022-04577-8

Products & Services: Protein and Antibody Isolation

Crystal structures and functional analysis of the ZnF5-WWE1-WWE2 region of PARP13/ZAP define a distinctive mode of engaging poly(ADP-ribose)

Authors: Jijin R A Kuttiyatveetil, Heddy Soufari, Morgan Dasovich, Isabel R Uribe, Manija Mirhasan, Shang-Jung Cheng, Anthony K L Leung, John M Pascal

Journal: Cell Rep

PubMed ID: 36288691

Doi: 10.1016/j.celrep.2022.111529

Products & Services: Mutant Libraries

Multiplex Detection of Antibody Landscapes to Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2)/Influenza/Common Human Coronaviruses Following Vaccination or Infection With SARS-CoV-2 and Influenza

Authors: Zhu Nan Li, Feng Liu, Stacie Jefferson, Lauren Horner, Paul Carney, Michael D L Johnson, Jennifer P King, Emily T Martin, Richard K Zimmerman, Karen Wernli, Manjusha Gaglani, Mark Thompson, Brendan Flannery, James Stevens, Terrence Tumpey, Min Z Levine

Journal: Clin Infect Dis

PubMed ID: 35684961

Doi: 10.1093/cid/ciac472

Products & Services: Stable Cell Lines