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Peroxynitrite in the tumor microenvironment changes the profile of antigens allowing escape from cancer immunotherapy

Authors: Evgenii N Tcyganov, Emilio Sanseviero, Douglas Marvel, Thomas Beer, Hsin-Yao Tang, Peter Hembach, David W Speicher, Qianfei Zhang, Laxminarasimha R Donthireddy, Ali Mostafa, Sabina Tsyganova, Vladimir Pisarev, Terri Laufer, Dmitriy Ignatov, Soldano Ferrone, Christiane Meyer, Hélène Maby-El Hajjami, Daniel E Speiser, Sooner Altiok, Scott Antonia, Xiaowei Xu, Wei Xu, Cathy Zheng, Lynn M Schuchter, Ravi K Amaravadi, Tara C Mitchell, Giorgos C Karakousis, Zhe Yuan, Luis J Montaner, Esteban Celis, Dmitry I Gabrilovich

Journal: Cancer Cell

PubMed ID: 36220073

Doi: 10.1016/j.ccell.2022.09.001

Products & Services: Peptide Synthesis

Chitosan and chitosan oligosaccharide influence digestibility of whey protein isolate through electrostatic interaction

Authors: Linlin Wang, Lilong Wang, Chengrong Wen, Nan Wang, Chunhong Yan, Caihong Shen, Shuang Song

Journal: Int J Biol Macromol

PubMed ID: 36191784

Doi: 10.1016/j.ijbiomac.2022.09.258

Products & Services: Protein and Antibody Isolation

Bridging the gap between maleate hydratase, citraconase and isopropylmalate isomerase: Insights into the single broad-specific enzyme

Authors: Akila Thirumalai, Padmapriya Ganapathy Raman, Tamilselvan Jayavelu, Ramalingam Subramanian

Journal: Enzyme Microb Technol

PubMed ID: 36272242

Doi: 10.1016/j.enzmictec.2022.110140

Products & Services: Bacterial Expression

Neutralizing and interfering human antibodies define the structural and mechanistic basis for antigenic diversion

Authors: Palak N Patel, Thayne H Dickey, Christine S Hopp, Ababacar Diouf, Wai Kwan Tang, Carole A Long, Kazutoyo Miura, Peter D Crompton, Niraj H Tolia

Journal: Nat Commun

PubMed ID: 36202833

Doi: 10.1038/s41467-022-33336-3

Products & Services: Mammalian Expression

Development of Enzymatic Depletion Methods for Preparation of Small Extracellular Vesicles with Long Blood-Circulation Half-Life

Authors: Yuki Kobayashi, Shimpei Kitamura, Yuki Takahashi, Yoshinobu Takakura

Journal: Pharm Res

PubMed ID: 36195822

Doi: 10.1007/s11095-022-03405-9

Products & Services: Protein and Antibody Isolation

Booster vaccination is required to elicit and maintain COVID-19 vaccine-induced immunity in SIV-infected macaques

Authors: Pingchao Li, Qian Wang, Yizi He, Chenchen Yang, Zhengyuan Zhang, Zijian Liu, Bo Liu, Li Yin, Yilan Cui, Peiyu Hu, Yichu Liu, Pingqian Zheng, Wei Wang, Linbing Qu, Caijun Sun, Suhua Guan, Liqiang Feng, Ling Chen

Journal: Emerg Microbes Infect

PubMed ID: 36239345

Doi: 10.1080/22221751.2022.2136538

Products & Services: Catalog Peptides

Allosteric regulation of glycogen breakdown by the second messenger cyclic di-GMP

Authors: Maria A Schumacher, Mirka E Wörmann, Max Henderson, Raul Salinas, Andreas Latoscha, Mahmoud M Al-Bassam, Kumar Siddharth Singh, Elaine Barclay, Katrin Gunka, Natalia Tschowri

Journal: Nat Commun

PubMed ID: 36192422

Doi: 10.1038/s41467-022-33537-w

Products & Services: PCR Cloning and Subcloning

Targeting SARS-CoV-2 infection through CAR-T-like bispecific T cell engagers incorporating ACE2

Authors: Mikail Dogan, Lina Kozhaya, Lindsey Placek, Fatih Karabacak, Mesut Yigit, Derya Unutmaz

Journal: Clin Transl Immunology

PubMed ID: 36285327

Doi: 10.1002/cti2.1421

Products & Services: Protein and Antibody Isolation

A non-canonical RNA-binding domain of the Fragile X protein, FMRP, elicits translational repression independent of mRNA G-quadruplexes

Authors: MaKenzie R Scarpitti, Julia E Warrick, Evelyn L Yoder, Michael G Kearse

Journal: J Biol Chem

PubMed ID: 36328245

Doi: 10.1016/j.jbc.2022.102660

Products & Services: Bacterial Expression

Construction of a bioluminescence-based assay for bitter taste receptors (TAS2Rs)

Authors: Shi Min Tan, Wei-Guang Seetoh

Journal: Sci Rep

PubMed ID: 36271274

Doi: 10.1038/s41598-022-21678-3

Products & Services: Mammalian Expression