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POSTN-Mediated Interplay of M1 Polarized Macrophage with Tendon-Derived Stem Cells to Drive Traumatic Heterotopic Ossification Formation through PTK7/ATK Signaling?
Authors: Hang Liu, Xinyue Li, Mengyi Li, Ziyang Sun, Xu Wang, Juehong Li, Binbin Xu, Qian Chen, Cunyi Fan, Hongjiang Ruan
Journal: Advanced Science
PubMed ID: 40823759
Doi: 10.1002/advs.202507951
Products & Services: Custom Vector Construction   
Structural convergence and water-mediated substrate mimicry enable broad neuraminidase inhibition by human antibodies
Authors: Julia Lederhofer, Andrew J Borst, Lam Nguyen, Rebecca A Gillespie, Connor J Williams, Emma L Walker, Julie E Raab, Christina Yap, Daniel Ellis, Adrian Creanga, Hyon-Xhi Tan, Thi H T Do, Michelle Ravichandran, Adrian B McDermott, Valerie Le Sage, Sarah F Andrews, Barney S Graham, Adam K Wheatley, Douglas S Reed, Neil P King, Masaru Kanekiyo
Journal: Nature Communications
PubMed ID: 40750617
Doi: 10.1038/s41467-025-62339-z.
Products & Services: Custom Vector Construction   
An Apple Susceptibility-Related LRR Receptor-Like Kinase MdRLKT21 Activates Plant Immunity by Hijacking a Trans-Kingdom Fungal microRNA-Like RNA
Authors: Mingliang Lei, Jian Zhang, Jie Wang, Chengyu Gao, Yanting He, Runze Tian, Hao Feng, Lili Huang
Journal: Advanced Science
PubMed ID: 40755370
Doi: 10.1002/advs.202417426
Identification of distinct epitopes in dipeptidyl peptidase-4 inhibitor-associated bullous pemphigoid
Authors: Shoko Mai https://orcid.org/0000-0001-5468-6851, Yosuke Mai https://orcid.org/0000-0001-6356-7192, Inkin Ujiie https://orcid.org/0000-0002-7931-949X, Kentaro Izumi https://orcid.org/0000-0001-8221-9644, Ken Natsuga https://orcid.org/0000-0003-3865-6366, Wataru Nishie https://orcid.org/0000-0002-0486-9112, and Hideyuki Ujiie
Journal: SCIENCE ADVANCES
PubMed ID: 40749047
Doi: 10.1126/sciadv.adv9423
Products & Services: Custom Vector Construction   
High-throughput investigation of cyclin docking interactions reveals the complexity of motif binding determinants
Authors: Mihkel Örd, Matthew J Winters, Mythili S Subbanna, Natàlia de Martín Garrido, Victoria I Cushing, Johanna Kliche, Caroline Benz, Ylva Ivarsson, Basil J Greber, Peter M Pryciak, Norman E Davey
Journal: Nature Communications
PubMed ID: 40817109
Doi: 10.1038/s41467-025-62765-z.
Products & Services: Peptide Synthesis   
Lipid interactions and gating hysteresis suggest a physiological role for mechanosensitive channel YnaI
Authors: Nathan Will, Giorgos Hiotis, Yoshitaka Nakayama, Gabriella Angiulli, Zijing Zhou, Charles D Cox, Boris Martinac, Thomas Walz
Journal: Nature Communications
PubMed ID: 40796571
Doi: 10.1038/s41467-025-62805-8.
Products & Services: PCR Cloning and Subcloning   
HIV broadly neutralizing antibody precursors to the Apex epitope induced in nonhuman primates
Authors: Krystal M Ma, Henry J Sutton, Payal P Pratap, Jon M Steichen, Diane Carnathan, James Quinn, Oleksandr Kalyuzhniy, Alessia Liguori, Sashank Agrawal, Sabyasachi Baboo, Patrick Madden, Christopher A Cottrell, Jordan R Willis, Jeong-Hyun Lee, Elise Landais, Xiaozhen Hu, Parham Ramezani-Rad, Gabriel Ozorowski, Vanessa R Lewis, Jolene K Diedrich, Xiaoya Zhou, Tasha K Altheide, Nicole Phelps, Erik Georgeson, Nushin B Alavi, Danny Lu, Saman Eskandarzadeh, Michael Kubitz, Yumiko Adachi, Tina-Marie Mullen, Murillo Silva, Mariane B Melo, Sunny Himansu, Darrell J Irvine, Dennis R Burton, John R Yates 3rd, James C Paulson, Devin Sok, Ian A Wilson, Guido Silvestri, Andrew B Ward, Shane
Journal: Science immunology
PubMed ID: 40845127
Doi: 10.1126/sciimmunol.adt6660
Products & Services: Recombinant Antibody Expression   
DeFrND: detergent-free reconstitution into native nanodiscs with designer membrane scaffold peptides
Authors: Qian Ren, Jing Wang, Vinay Idikuda, Shanwen Zhang, Jeehae Shin, W Grant Ludlam, Luis M Real Hernandez, Sara Zdancewicz, Alex J B Kreutzberger, Hucheng Chang, Volker Kiessling, Lukas K Tamm, Ahmad Jomaa, Ilya Levental, Kirill Martemyanov, Baron Chanda, Huan Bao, Dhanya Thamaraparambil Jayaram, Pranav Sivaram, Pranjal Biswas, Yue Dai, Elizabeth A Sweeny, Dennis J Stuehr
Journal: Nature Communications
PubMed ID: 40858559
Doi: 10.1038/s41467-025-63275-8.
Products & Services: Protein and Antibody Isolation   
Discovery of CRISPR-Cas12a clades using a large language model
Authors: Yuanyuan Feng, Junchao Shi, Zhanwei Li, Yongqian Li, Jiaxi Yang, Shisheng Huang, Jinfang Zheng, Wei Han, Yunbo Qiao, Jun Zhang, Qi Liu, Yao Yang, Chunyi Hu, Lina Wu, Xiaokang Zhang, Jin Tang, Xingxu Huang, Peixiang Ma
Journal: Nature Communications
PubMed ID: 40849498
Doi: 10.1038/s41467-025-63160-4.
Products & Services: Synthetic Guide RNA   
Lung metastasis and recurrence is mitigated by CARmacrophages, in-situ-generated from mRNA delivered by small extracellular vesicles
Authors: Yuchen Xiao, Tianchuan Zhu, Zhenxing Chen, Xi Huang
Journal: Nature Communications
PubMed ID: 40759657
Doi: 10.1038/s41467-025-62506-2
Products & Services: Custom DNA/RNA Oligos   
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