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The Immunological Epigenetic Landscape of the Human Life Trajectory

Authors: Iva Juříčková, Michael Hudec, Felix Votava, Jan Vosáhlo, Saak Victor Ovsepian, Marie Černá, Valerie Bríd O'Leary

Journal: Biomedicines

PubMed ID: 36428462

Doi: 10.3390/biomedicines10112894

Products & Services: Molecular Biology Tools

ATG9A and ATG2A form a heteromeric complex essential for autophagosome formation

Authors: Alexander R van Vliet, George N Chiduza, Sarah L Maslen, Valerie E Pye, Dhira Joshi, Stefano De Tito, Harold B J Jefferies, Evangelos Christodoulou, Chloë Roustan, Emma Punch, Javier H Hervás, Nicola O'Reilly, J Mark Skehel, Peter Cherepanov, Sharon A Tooze

Journal: Mol Cell

PubMed ID: 36347259

Doi: 10.1016/j.molcel.2022.10.017

Products & Services: Protein and Antibody Isolation

Functional and molecular dissection of HCMV long non-coding RNAs

Authors: Sungwon Lee, Hyewon Kim, Ari Hong, Jaewon Song, Sungyul Lee, Myeonghwan Kim, Sung-Yeon Hwang, Dongjoon Jeong, Jeesoo Kim, Ahyeon Son, Young-Suk Lee, V Narry Kim, Jong-Seo Kim, Hyeshik Chang, Kwangseog Ahn

Journal: Sci Rep

PubMed ID: 36369338

Doi: 10.1038/s41598-022-23317-3

Products & Services: Custom DNA/RNA Oligos

Evolutionary gain and loss of a plant pattern-recognition receptor for HAMP recognition

Authors: Simon Snoeck, Bradley W Abramson, Anthony G K Garcia, Ashley N Egan, Todd P Michael, Adam Steinbrenner

Journal: Elife

PubMed ID: 36377784

Doi: 10.7554/eLife.81050

Products & Services: Peptide Synthesis

A novel humanized Chi3l1 blocking antibody attenuates acetaminophen-induced liver injury in mice

Authors: Leike Li, Yankai Wen, Daniel Wrapp, Jongmin Jeong, Peng Zhao, Wei Xiong, Constance Lynn Atkins, Zhao Shan, Deng Hui, Jason S McLellan, Ningyan Zhang, Cynthia Ju, Zhiqiang An

Journal: Antib Ther

PubMed ID: 36683763

Doi: 10.1093/abt/tbac027

Products & Services: Protein and Antibody Isolation

Epsilon-caprolactone-modified polyethylenimine as a genetic vehicle for stem cell-based bispecific antibody and exosome synergistic therapy

Authors: Yan Tan, Jiali Cai, Zhiyong Wang

Journal: Regen Biomater

PubMed ID: 36683744

Doi: 10.1093/rb/rbac090

Products & Services: Protein and Antibody Isolation

PNGase H + variant from Rudaea cellulosilytica with improved deglycosylation efficiency for rapid analysis of eukaryotic N-glycans and hydrogen deuterium exchange mass spectrometry analysis of glycoproteins

Authors: Rui-Rui Guo, Tian-Chan Zhang, Thomas Ole Tandrup Lambert, Ting Wang, Josef Voglmeir, Kasper D Rand, Li Liu

Journal: Rapid Commun Mass Spectrom

PubMed ID: 35945033

Doi: 10.1002/rcm.9376

Products & Services: Custom Vector Construction

Discovery and mechanism of action of Thonzonium bromide from an FDA-approved drug library with potent and broad-spectrum inhibitory activity against main proteases of human coronaviruses

Authors: Ruyu Wang, Guanglei Zhai, Guanghao Zhu, Mengge Wang, Xiaoyi Gong, Weidong Zhang, Guangbo Ge, Hongzhuan Chen, Lili Chen

Journal: Bioorg Chem

PubMed ID: 36395603

Doi: 10.1016/j.bioorg.2022.106264

Products & Services: Gene Synthesis

speedingCARs: accelerating the engineering of CAR T cells by signaling domain shuffling and single-cell sequencing

Authors: Rocío Castellanos-Rueda, Raphaël B Di Roberto, Florian Bieberich, Fabrice S Schlatter, Darya Palianina, Oanh T P Nguyen, Edo Kapetanovic, Heinz Läubli, Andreas Hierlemann, Nina Khanna, Sai T Reddy

Journal: Nat Commun

PubMed ID: 36323661

Doi: 10.1038/s41467-022-34141-8

Products & Services: Protein and Antibody Isolation

Mammalian Target of Rapamycin Inhibition Decreases Angiotensin II-Induced Steroidogenesis in HAC15 Human Adrenocortical Carcinoma Cells

Authors: Yusuf Ali, Elise P Gomez-Sanchez, Celso E Gomez-Sanchez

Journal: Endocrinology

PubMed ID: 36320101

Doi: 10.1210/endocr/bqac185

Products & Services: Gene Synthesis