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PD-L1/TLR7 dual-targeting nanobody-drug conjugate mediates potent tumor regression via elevating tumor immunogenicity in a host-expressed PDL1 bias-dependent way
Authors: Xiaolu Yu, Yiru Long , Binfan Chen , Yongliang Tong , Mengwen Shan , Xiaomin Jia , Chao Hu , Meng Liu , Ji Zhou , Feng Tang , Henglei Lu , Runqiu Chen , Pan Xu , Wei Huang , Jin Ren , Yakun Wan , Jianhua Sun , Jia Li , Guangyi Jin , Likun Gong
Journal: J Immunother Cancer .
PubMed ID: 36253000
Doi: 10.1136/jitc-2022-004590
Products & Services: Recombinant Proteins   
PCDetection: PolyA-CRISPR/Cas12a-based miRNA detection without PAM restriction
Authors: Mingtian Zhong , Kaizhao Chen , Wenjun Sun , Xiangyang Li , Shisheng Huang , Qingzhou Meng , Bo Sun , Xingxu Huang , Xinjie Wang , Xiaodong Ma , Peixiang Ma
Journal: Biosens Bioelectron
PubMed ID: 35797934
Doi: 10.1016/j.bios.2022.114497
Products & Services: Gene Synthesis   
Duration of antiretroviral therapy impacts the degree of residual SIV infection in the gut in long-term non-progressing Chinese rhesus macaques
Authors: Antonio Solis-Leal, Ann-Marie May, Mahesh Mohan, Jason P Dufour, Binhua Ling
Journal: J Med Virol
PubMed ID: 36181356
Doi: 10.1002/jmv.28185
Estrogen receptor β activation inhibits colitis by promoting NLRP6-mediated autophagy
Authors: Wentao Fan, Chenchen Ding, Shuhui Liu, Xiaona Gao, Xiaofei Shen, Marthe De Boevre, Zhangshan Gao, Mengcong Li, Shuo Zhang, Yufan Miao, Wenxian Guan, Guangliang Liu, Liping Yan, Sarah De Saeger, Suquan Song
Journal: Cell Rep
PubMed ID: 36223738
Doi: 10.1016/j.celrep.2022.111454
Fructose-6-phosphate-2-kinase/fructose-2,6-bisphosphatase regulates energy metabolism and synthesis of storage products in developing rice endosperm
Authors: Xiaoli Chen , Yi Ji , Weiying Zhao , Huanying Niu , Xue Yang , Xiaokang Jiang , Yipeng Zhang , Jie Lei , Hang Yang , Rongbo Chen , Chuanwei Gu , Hongyi Xu , Hui Dong , Erchao Duan , Xuan Teng , Yunlong Wang , Yuanyan Zhang , Wenwei Zhang , Yihua Wang , Jianmin Wan
Journal: Plant Sci
PubMed ID: 36270512
Doi: 10.1016/j.plantsci.2022.111503
The Detection of Immunity against WT1 and SMAD4 of EpCAM Cancer Cells in Malignant Pleural Effusion
Authors: Terutsugu Koya, Yo Niida, Misa Togi, Kenichi Yoshida, Takuya Sakamoto, Hiroki Ura, Sumihito Togi, Tomohisa Kato, Sohsuke Yamada, Haruo Sugiyama, Shigeo Koido, Shigetaka Shimodaira
Journal: Int J Mol Sci
PubMed ID: 36293034
Doi: 10.3390/ijms232012177
Products & Services: Peptide Synthesis   
Isobutanol production by combined and metabolic engineering
Authors: Mamta Gupta, Matthew Wong, Kamran Jawed, Kamil Gedeon, Hannah Barrett, Marcelo Bassalo, Clifford Morrison, Danish Eqbal, Syed Shams Yazdani, Ryan T Gill, Jiaqi Huang, Marc Douaisi, Jonathan Dordick, Georges Belfort, Mattheos A G Koffas
Journal: Metab Eng Commun
PubMed ID: 36325486
Doi: 10.1016/j.mec.2022.e00210
Products & Services: Plasmid DNA Preparation   
Multifunctional chemical inhibitors of the florigen activation complex discovered by structure-based high-throughput screening
Authors: Ken-Ichiro Taoka, Ikumi Kawahara, Shoko Shinya, Ken-Ichi Harada, Eiki Yamashita, Zenpei Shimatani, Kyoko Furuita, Tomoaki Muranaka, Tokitaka Oyama, Rie Terada, Atsushi Nakagawa, Toshimichi Fujiwara, Hiroyuki Tsuji, Chojiro Kojima
Journal: Plant J
PubMed ID: 36288411
Doi: 10.1111/tpj.16008
Products & Services: Peptide Synthesis   
The large plasmid carried class 1 integrons mediated multidrug resistance of foodborne Indiana
Authors: Xuefeng Wang, Tian Wang, Mengjiao Guo, Chengcheng Zhang, Zongyi Bo, Yantao Wu, Guoxiang Chao
Journal: Front Microbiol
PubMed ID: 36312970
Doi: 10.3389/fmicb.2022.991326
Products & Services: Custom DNA/RNA Oligos   
Development and characterization of a new monoclonal antibody against SARS-CoV-2 NSP12 (RdRp)
Authors: Wen Meng, Siying Guo, Simon Cao, Masahiro Shuda, Lindsey R Robinson-McCarthy, Kevin R McCarthy, Yoko Shuda, Alberto E Paniz Mondolfi, Clare Bryce, Zachary Grimes, Emilia M Sordillo, Carlos Cordon-Cardo, Pengfei Li, Hu Zhang, Stanley Perlman, Haitao Guo, Shou-Jiang Gao, Yuan Chang, Patrick S Moore
Journal: J Med Virol
PubMed ID: 36271490
Doi: 10.1002/jmv.28246
Products & Services: Peptide Synthesis   

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