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Prenatal diagnostic approaches diagnosed craniosynostosis and identified a novel nonsense variant in SMAD6 in a Chinese fetus

Authors: Zhidan Hong, Xuanyi He, Jie Duan, Fang Yu, Huanyu Liu, Dan Lu, Mei Wang, Yuanzhen Zhang

Journal: Gene

PubMed ID: 37977316

Doi: 10.1016/j.gene.2023.147994

Products & Services: Molecular Biology Reagents

A second-generation M1-polarized CAR macrophage with antitumor efficacy

Authors: Anhua Lei, Hua Yu, Shan Lu, Hengxing Lu, Xizhong Ding, Tianyu Tan, Hailing Zhang, Mengmeng Zhu, Lin Tian, Xudong Wang, Siyu Su, Dixuan Xue, Shaolong Zhang, Wei Zhao, Yuge Chen, Wanrun Xie, Li Zhang, Yuqing Zhu, Jing Zhao, Wenhong Jiang, George Church, Francis Ka-Ming Chan, Zhihua Gao, Jin Zhang

Journal: Nat Immunol

PubMed ID: 38012418

Doi: 10.1038/s41590-023-01687-8

Products & Services: Molecular Biology Reagents

Rational immunosilencing of a promiscuous T-cell epitope in the capsid of an adeno-associated virus

Authors: So Jin Bing, Morten Seirup, Trish T Hoang, Susana S Najera, Collin Britten, Stephanee L Warrington, Shiang-Ling Chu, Ronit Mazor

Journal: Nat Biomed Eng

PubMed ID: 37996615

Doi: 10.1038/s41551-023-01129-8

Products & Services: Peptide Synthesis

DNAJB6 mutants display toxic gain of function through unregulated interaction with Hsp70 chaperones

Authors: Meital Abayev-Avraham, Yehuda Salzberg, Dar Gliksberg, Meital Oren-Suissa, Rina Rosenzweig

Journal: Nat Commun

PubMed ID: 37923706

Doi: 10.1038/s41467-023-42735-z

Products & Services: Protein and Antibody Isolation

Critical role of TPRN rings in the stereocilia for hearing

Authors: Jieyu Qi, Fangzhi Tan, Liyan Zhang, Yinyi Zhou, Ziyu Zhang, Qiuhan Sun, Nianci Li, Yuan Fang, Xin Chen, Yunhao Wu, Guisheng Zhong, Renjie Chai

Journal: Mol Ther

PubMed ID: 37952086

Doi: 10.1016/j.ymthe.2023.11.011

Products & Services: Protein and Antibody Isolation

Interactions of Histone Deacetylase 6 with DNA Damage Repair Factors Strengthen its Utility as a Combination Drug Target in High-Grade Serous Ovarian Cancer

Authors: Jolene M Duda, Stefani N Thomas

Journal: ACS Pharmacol Transl Sci

PubMed ID: 38107255

Doi: 10.1021/acsptsci.3c00215

Products & Services: Protein and Antibody Isolation

Single-injection subunit vaccine for rabies prevention using lentinan as adjuvant

Authors: Xiaoyong Zhou, Haozheng Wang, Jianchen Zhang, Ying Guan, Yongjun Zhang

Journal: Int J Biol Macromol

PubMed ID: 37977452

Doi: 10.1016/j.ijbiomac.2023.128118

Products & Services: Protein and Antibody Isolation

A role for cytoglobin in regulating intracellular hydrogen peroxide and redox signals in the vasculature

Authors: Clinton Mathai, Frances Jourd'heuil, Le Gia Cat Pham, Kurrim Gilliard, Joseph Balnis, Annie Jen, Katherine A Overmyer, Joshua J Coon, Ariel Jaitovich, Benoit Boivin, David Jourd'heuil

Journal: biorxiv

PubMed ID: 37034694

Doi: 10.1101/2023.03.31.535146

Products & Services: Protein and Antibody Isolation

Allosteric coupling of substrate binding and proton translocation in MmpL3 transporter from Mycobacterium tuberculosis

Authors: Svitlana Babii; Wei Li; Lixinhao Yang; Anna E. Grzegorzewicz; Mary Jackson; James C. Gumbart; Helen I. Zgurskaya

Journal: MBio

PubMed ID: 39212407

Doi: 10.1128/mbio.02183-24

Products & Services: Mutagenesis Services

Allosteric coupling of substrate binding and proton translocation in MmpL3 transporter from Mycobacterium tuberculosis

Authors: Svitlana Babii; Wei Li; Lixinhao Yang; Anna E. Grzegorzewicz; Mary Jackson; James C. Gumbart; Helen I. Zgurskaya

Journal: MBio

PubMed ID: 39212407

Doi: 10.1128/mbio.02183-24

Products & Services: Mutagenesis Services