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Functionalized biomimetic nanoparticles combining programmed death-1/programmed death-ligand 1 blockade with photothermal ablation for enhanced colorectal cancer immunotherapy.

Authors: Yuchen Xiao, Tianchuan Zhu, Qi Zeng, Qingqin Tan, Guanmin Jiang, Xi Huang

Journal: Acta Biomater

PubMed ID: 36442821

Doi: 10.1016/j.actbio.2022.11.043

Products & Services: Protein and Antibody Isolation

ACE2 binding and antibody evasion in enhanced transmissibility of XBB15

Authors: Can Yue, Weiliang Song, Lei Wang, Fanchong Jian, Xiaosu Chen, Fei Gao, Zhongyang Shen, Youchun Wang, Xiangxi Wang, Yunlong Cao

Journal: Lancet Infect Dis

PubMed ID: 36746173

Doi: 10.1016/S1473-3099(23)00010-5

Products & Services: Protein and Antibody Isolation

Design of a Tumor Binding GMCSF as Intratumoral Immunotherapy of Solid Tumors

Authors: Aparna Raghavachar Chakravarti, Chad E Groer, Huan Gong, Vivian Yudistyra, Marcus Laird Forrest, Cory J Berkland

Journal: Mol Pharm

PubMed ID: 36825806

Doi: 10.1021/acs.molpharmaceut.2c00897

Products & Services: Gene Synthesis

Somatically hypermutated antibodies isolated from SARS-CoV-2 Delta infected patients cross-neutralize heterologous variants

Authors: Haisheng Yu, Banghui Liu, Yudi Zhang, Xijie Gao, Qian Wang, Haitao Xiang, Xiaofang Peng, Caixia Xie, Yaping Wang, Peiyu Hu, Jingrong Shi, Quan Shi, Pingqian Zheng, Chengqian Feng, Guofang Tang, Xiaopan Liu, Liliangzi Guo, Xiumei Lin, Jiaojiao Li, Chuanyu Liu, Yaling Huang, Naibo Yang, Qiuluan Chen, Zimu Li, Mengzhen Su, Qihong Yan, Rongjuan Pei, Xinwen Chen, Longqi Liu, Fengyu Hu, Dan Liang, Bixia Ke, Changwen Ke, Feng Li, Jun He, Meiniang Wang, Ling Chen, Xiaoli Xiong, Xiaoping Tang

Journal: Nat Commun

PubMed ID: 36828833

Doi: 10.1038/s41467-023-36761-0

Products & Services: Recombinant Antibody Expression

Cooperation of N- and C-terminal substrate transmembrane domain segments in intramembrane proteolysis by γ-secretase

Authors: Nadine T Werner, Philipp Högel, Gökhan Güner, Walter Stelzer, Manfred Wozny, Marlene Aßfalg, Stefan F Lichtenthaler, Harald Steiner, Dieter Langosch

Journal: Commun Biol

PubMed ID: 36792683

Doi: 10.1038/s42003-023-04470-5

Products & Services: Gene Synthesis

Expression, purification, and characterisation of the p53 binding domain of Retinoblastoma binding protein 6 (RBBP6)

Authors: Bonnie L Russell, Monde Ntwasa

Journal: PLoS ONE

PubMed ID: 36763571

Doi: 10.1371/journal.pone.0277478

Products & Services: Protein and Antibody Isolation

CYCLIN-DEPENDENT KINASE 8 positively regulates oil synthesis by activating WRINKLED1 transcription

Authors: Zhiyang Zhai, Jantana K Blanford, Yingqi Cai, Jing Sun, Hui Liu, Hai Shi, Jorg Schwender, John Shanklin

Journal: New Phytol

PubMed ID: 36683527

Doi: 10.1111/nph.18764

Products & Services: Monoclonal Antibody Services

LAPTM5 regulated by FOXP3 promotes the malignant phenotypes of breast cancer through activating the Wnt/β‑catenin pathway

Authors: Sijia Han, Xueying Jin, Tianyu Hu, Feng Chi

Journal: Oncol Rep

PubMed ID: 36799186

Doi: 10.3892/or.2023.8497

Products & Services: Stable Cell Lines

Loss of LGR4/GPR48 causes severe neonatal salt wasting due to disrupted WNT signaling altering adrenal zonation

Authors: Cécily Lucas, Kay-Sara Sauter, Michael Steigert, Delphine Mallet, James Wilmouth, Julie Olabe, Ingrid Plotton, Yves Morel, Daniel Aeberli, Franca Wagner, Hans Clevers, Amit V Pandey, Pierre Val, Florence Roucher-Boulez, Christa E Flück

Journal: JOURNAL OF CLINICAL INVESTIGATION

PubMed ID: 36538378

Doi: 10.1172/JCI164915

Products & Services: Protein and Antibody Isolation

MTORC2 is a physiological hydrophobic motif kinase of S6 Kinase 1

Authors: Sheikh Tahir Majeed, Rabiya Majeed, Aijaz A Malik, Khurshid Iqbal Andrabi

Journal: Biochim Biophys Acta Mol Cell Res

PubMed ID: 36858209

Doi: 10.1016/j.bbamcr.2023.119449

Products & Services: Catalog Peptides