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CriSNPr, a single interface for the curated and de novo design of gRNAs for CRISPR diagnostics using diverse Cas systems
Authors: Asgar H Ansari, Manoj Kumar, Sajal Sarkar, Souvik Maiti, Debojyoti Chakraborty
Journal: Elife
PubMed ID: 36752591
Doi: 10.7554/eLife.77976
Products & Services: Protein and Antibody Isolation   
Dynamic states of eIF6 and SDS variants modulate interactions with uL14 of the 60S ribosomal subunit
Authors: Jonah Elliff, Aparna Biswas, Poonam Roshan, Sahiti Kuppa, Angela Patterson, Jenna Mattice, Mathivanan Chinnaraj, Ryan Burd, Sarah E Walker, Nicola Pozzi, Edwin Antony, Brian Bothner, Sofia Origanti
Journal: Nucleic Acids Res
PubMed ID: 36651285
Doi: 10.1093/nar/gkac1266
Products & Services: Protein and Antibody Isolation   
Broadly neutralizing SARS-CoV-2 antibodies through epitope-based selection from convalescent patients
Authors: Romain Rouet, Jake Y Henry, Matt D Johansen, Meghna Sobti, Harikrishnan Balachandran, David B Langley, Gregory J Walker, Helen Lenthall, Jennifer Jackson, Stephanie Ubiparipovic, Ohan Mazigi, Peter Schofield, Deborah L Burnett, Simon H J Brown, Marianne Martinello, Bernard Hudson, Nicole Gilroy, Jeffrey J Post, Anthony Kelleher, Hans-Martin Jäck, Christopher C Goodnow, Stuart G Turville, William D Rawlinson, Rowena A Bull, Alastair G Stewart, Philip M Hansbro, Daniel Christ
Journal: Nat Commun
PubMed ID: 36755042
Doi: 10.1038/s41467-023-36295-5
Products & Services: Protein and Antibody Isolation   
Single-Molecule Interconversion between Chiral Configurations of Boronate Esters Observed in a Nanoreactor
Authors: Xiaoyu Du, Shanyu Zhang, Liying Wang, Yuqin Wang, Pingping Fan, Wendong Jia, Panke Zhang, Shuo Huang
Journal: ACS Nano
PubMed ID: 36655995
Doi: 10.1021/acsnano.2c11286
Products & Services: Plasmid DNA Preparation   
The activation mechanism and antibody binding mode for orphan GPR20
Authors: Xi Lin, Shan Jiang, Yiran Wu, Xiaohu Wei, Gye-Won Han, Lijie Wu, Junlin Liu, Bo Chen, Zhibin Zhang, Suwen Zhao, Vadim Cherezov, Fei Xu
Journal: Cell Discovery
PubMed ID: 36849514
Doi: 10.1038/s41421-023-00520-8
Products & Services: Gene Synthesis   
The molecular mechanism of light-induced bond formation and breakage in the cyanobacteriochrome TePixJ
Authors: Jeannette Ruf, Flavia Bindschedler, David Buhrke
Journal: Phys Chem Chem Phys
PubMed ID: 36752541
Doi: 10.1039/d2cp05856a
Products & Services: Protein and Antibody Isolation   
Efficient hydroxylation of flavonoids by using whole-cell P450 sca-2 biocatalyst in
Authors: Baodong Hu, Xinrui Zhao, Jingwen Zhou, Jianghua Li, Jian Chen, Guocheng Du
Journal: Front Bioeng Biotechnol
PubMed ID: 36873357
Doi: 10.3389/fbioe.2023.1138376
Products & Services: Gene Synthesis   
Fused human paraoxonase 1 as a prophylactic agent against organophosphate poisoning
Authors: Prakashkumar Dobariya, Pratik Adhya, Bhupesh Vaidya, Prakash Y Khandave, Shyam Sunder Sharma, Abhay H Pande
Journal: Enzyme Microb Technol
PubMed ID: 36764031
Doi: 10.1016/j.enzmictec.2023.110209
Products & Services: Molecular Biology Reagents   
A rapid nucleic acid detection platform based on phosphorothioate-DNA and sulfur binding domain
Authors: Yuting Shuai, Yi Ju, Yuanhang Li, Dini Ma, Lan Jiang, Jingyu Zhang, Gao-Yi Tan, Xueting Liu, Shenlin Wang, Lixin Zhang, Guang Liu
Journal: Synth Syst Biotechnol
PubMed ID: 36875498
Doi: 10.1016/j.synbio.2023.02.002
Products & Services: Protein and Antibody Isolation   
Drug repurposing screens identify compounds that inhibit α-synuclein oligomers' membrane disruption and block antibody interactions
Authors: Arun Kumar Somavarapu, Giulia Kleijwegt, Madhu Nagaraj, Parvez Alam, Janni Nielsen, Daniel E Otzen
Journal: Chem Sci
PubMed ID: 36937574
Doi: 10.1039/d2sc05534a
Products & Services: Recombinant Proteins   
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