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Repeated Omicron exposures override ancestral SARS-CoV-2 immune imprinting

Authors: Ayijiang Yisimayi, Weiliang Song, Jing Wang, Fanchong Jian, Yuanling Yu, Xiaosu Chen, Yanli Xu, Sijie Yang, Xiao Niu, Tianhe Xiao, Jing Wang , Lijuan Zhao, Haiyan Sun, Ran An, Na Zhang, Yao Wang, Peng Wang, Lingling Yu, Zhe Lv, Qingqing Gu, Fei Shao, Ronghua Jin, Zhongyang Shen, Xiaoliang Sunney Xie, Youchun Wang, Yunlong Cao

Journal: Nature

PubMed ID: 37993710

Doi: 10.1038/s41586-023-06753-7

Products & Services: Gene Synthesis

Structural basis of Gabija anti-phage defence and viral immune evasion

Authors: Sadie P Antine, Alex G Johnson, Sarah E Mooney, Azita Leavitt, Megan L Mayer, Erez Yirmiya, Gil Amitai, Rotem Sorek, Philip J Kranzusch

Journal: Nature

PubMed ID: 37992757

Doi: 10.1038/s41586-023-06855-2

Products & Services: Gene Synthesis

A synthetic differentiation circuit in Escherichia coli for suppressing mutant takeover

Authors: David S Glass 1, Anat Bren 2, Elizabeth Vaisbourd 2, Avi Mayo 2, Uri Alon

Journal: Cell

PubMed ID: 38320549

Doi: 10.1016/j.cell.2024.01.024

Products & Services: Plasmid DNA Preparation

Sirtuin 3 is required for the dexmedetomidine-mediated alleviation of inflammation and oxidative stress in nephritis

Authors: Kai Lu , Xinlong Li , Jie Wu

Journal: Immunity

PubMed ID: 38270316

Doi: 10.1002/iid3.1135

Products & Services: Custom DNA/RNA Oligos

Selective CK1α degraders exert antiproliferative activity against a broad range of human cancer cell lines

Authors: Gisele Nishiguchi , Lauren G Mascibroda , Sarah M Young , Elizabeth A Caine , Sherif Abdelhamed , Jeffrey J Kooijman , Darcie J Miller , Sourav Das , Kevin McGowan , Anand Mayasundari , Zhe Shi , Juan M Barajas , Ryan Hiltenbrand , Anup Aggarwal , Yunchao Chang , Vibhor Mishra , Shilpa Narina , Melvin Thomas , Allister J Loughran , Ravi Kalathur , Kaiwen Yu , Suiping Zhou , Xusheng Wang , Anthony A High , Junmin Peng , Shondra M Pruett-Miller , Danette L Daniels , Marjeta Urh , Anang A Shelat , Charles G Mullighan , Kristin M Riching , Guido J R Zaman , Marcus Fischer , Jeffery M Klco , Zoran Rankovic

Journal: Nat Commun

PubMed ID: 38228616

Doi: 10.1038/s41467-024-44698-1

Products & Services: Custom Vector Construction

PIEZO1 loss-of-function compound heterozygous mutations in the rare congenital human disorder Prune Belly Syndrome

Authors: Nathalia G Amado , Elena D Nosyreva , David Thompson , Thomas J Egeland , Osita W Ogujiofor , Michelle Yang , Alexandria N Fusco , Niccolo Passoni , Jeremy Mathews , Brandi Cantarel , Linda A Baker , Ruhma Syeda

Journal: Nat Commun

PubMed ID: 38184690

Doi: 10.1038/s41467-023-44594-0

Products & Services: PCR Cloning and Subcloning

A stapled lipopeptide platform for preventing and treating highly pathogenic viruses of pandemic potential

Authors: Gregory H Bird , J J Patten , William Zavadoski , Nicole Barucci , Marina Godes , Benjamin M Moyer , Callum D Owen , Paul DaSilva-Jardine , Donna S Neuberg , Richard A Bowen , Robert A Davey , Loren D Walensky

Journal: Nat Commun

PubMed ID: 38177138

Doi: 10.1038/s41467-023-44361-1

Products & Services: Plasmid DNA Preparation

Massively parallel profiling of RNA-targeting CRISPR-Cas13d

Authors: Hung-Che Kuo , Joshua Prupes , Chia-Wei Chou , Ilya J Finkelstein

Journal: Nat Commun

PubMed ID: 37034598

Doi: 10.1101/2023.03.27.534188

Products & Services: Custom Vector Construction

Correlations of receptor desensitization of gain-of-function GABRB3 variants with clinical severity

Authors: Susan X N Lin, Philip K Ahring, Angelo Keramidas, Vivian W Y Liao, Rikke S Møller, Mary Chebib, Nathan L Absalom

Journal: Brain

PubMed ID: 37647766

Doi: 10.1093/brain/awad285

Products & Services: Plasmid DNA Preparation

Let-7a-5p Regulates Animal Lipid Accumulation by Targeting Srebf2 and Thbs1 Signaling

Authors: Jiahao Shao , Genglong Jiang , Yanhong Li, Meigui Wang, Tao Tang, Jie Wang , Xianbo Jia and Songjia Lai

Journal: Int. J. Mol. Sci

Doi: 10.3390/ijms25020894

Products & Services: Protein Electrophoresis and Western