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Clinical assays rapidly predict bacterial susceptibility to monoclonal antibody therapy

Authors: Matthew J Slarve, Neven Bowler, Elizabeth Burk, Jun Yan, Ulrike Carlino-MacDonald, Thomas A Russo, Brian M Luna, Brad Spellberg

Journal: JCI Insight

PubMed ID: 38258902

Doi: 10.1172/jci.insight.174799

Products & Services: Gene Synthesis

B-Type Natriuretic Peptide Inhibits the Expression and Function of SERCA2a in Heart Failure

Authors: Yuting Zhai, Junhong Chen, Rongsheng Kan, Haochen Xuan, Chaofan Wang, Dongye Li, Tongda Xu

Journal: Int Heart J

PubMed ID: 38556337

Doi: 10.1536/ihj.23-144

Products & Services: Molecular Biology Reagents

Recombinant protein expression in proteome-reduced cells under aerobic and oxygen-limited regimes

Authors: Alvaro R Lara, Jose Utrilla, Luz María Martínez, Niels Krausch, Lucas Kaspersetz, David Hidalgo, Nicolas Cruz-Bournazou, Peter Neubauer, Juan-Carlos Sigala, Guillermo Gosset, Jochen Büchs

Journal: Biotechnol Bioeng

PubMed ID: 38178599

Doi: 10.1002/bit.28645

Products & Services: Molecular Biology Reagents

The CRISPR effector Cam1 mediates membrane depolarization for phage defence

Authors: Christian F. Baca, You Yu, Jakob T. Rostøl, Puja Majumder, Dinshaw J. Patel & Luciano A. Marraffini

Journal: Nature

PubMed ID: 38200316

Doi: 10.1038/s41586-023-06902-y

Products & Services: Catalog Gene Editing

PARP1-DNA co-condensation drives DNA repair site assembly to prevent disjunction of broken DNA ends

Authors: Nagaraja Chappidi 1, Thomas Quail 2, Simon Doll 3, Laura T Vogel 4, Radoslav Aleksandrov 5, Suren Felekyan 4, Ralf Kühnemuth 4, Stoyno Stoynov 5, Claus A M Seidel 4, Jan Brugués 6, Marcus Jahnel 3, Titus M Franzmann 1, Simon Alberti

Journal: Cell

PubMed ID: 38320550

Doi: 10.1016/j.cell.2024.01.015

Products & Services: Codon Optimization Gene Synthesis

Identification of TMEM126A as OXA1L-interacting protein reveals cotranslational quality control in mitochondria

Authors: Sabine Poerschke, Silke Oeljeklaus, Luis Daniel Cruz-Zaragoza, Alexander Schenzielorz, Drishan Dahal, Hauke Sven Hillen, Hirak Das, Laura Sophie Kremer, Anusha Valpadashi, Mirjam Breuer, Johannes Sattmann, Ricarda Richter-Dennerlein, Bettina Warscheid, Sven Dennerlein, Peter Rehling

Journal: Cell

PubMed ID: 38199007

Doi: 10.1016/j.molcel.2023.12.013

Products & Services: Gene Synthesis

Terminal modifications independent cell-free RNA sequencing enables sensitive early cancer detection and classification

Authors: Jun Wang , Jinyong Huang , Yunlong Hu , Qianwen Guo , Shasha Zhang , Jinglin Tian , Yanqin Niu , Ling Ji , Yuzhong Xu , Peijun Tang , Yaqin He , Yuna Wang , Shuya Zhang , Hao Yang , Kang Kang , Xinchun Chen , Xinying Li , Ming Yang , Deming Gou

Journal: Nat Commun

PubMed ID: 38168054

Doi: 10.1038/s41467-023-44461-y

Products & Services: Gene Synthesis

Leafhopper salivary vitellogenin mediates virus transmission to plant phloem

Authors: Yanfei Wang , Chengcong Lu , Shude Guo , Yuxin Guo , Taiyun Wei , Qian Chen

Journal: Nat Commun

PubMed ID: 38167823

Doi: 10.1038/s41467-023-43488-5

Products & Services: Polyclonal Antibody Services

Fatty acid synthesis suppresses dietary polyunsaturated fatty acid use

Authors: Anna Worthmann , Julius Ridder , Sharlaine Y L Piel , Ioannis Evangelakos , Melina Musfeldt , Hannah Voß , Marie O'Farrell , Alexander W Fischer , Sangeeta Adak , Monica Sundd , Hasibullah Siffeti , Friederike Haumann , Katja Kloth , Tatjana Bierhals , Markus Heine , Paul Pertzborn , Mira Pauly , Julia-Josefine Scholz , Suman Kundu , Marceline M Fuh , Axel Neu , Klaus Tödter , Maja Hempel , Uwe Knippschild , Clay F Semenkovich , Hartmut Schlüter , Joerg Heeren , Ludger Scheja , Christian Kubisch , Christian Schlein

Journal: Nat Commun

PubMed ID: 38167725

Doi: 10.1038/s41467-023-44364-y

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Rif2 interaction with Rad50 counteracts Tel1 functions in checkpoint signalling and DNA tethering by releasing Tel1 from MRX binding

Authors: Paolo Pizzul, Erika Casari, Carlo Rinaldi, Marco Gnugnoli, Marco Mangiagalli, Renata Tisi, Maria Pia Longhese

Journal: Nucleic Acids Res

PubMed ID: 38180815

Doi: 10.1093/nar/gkad1246

Products & Services: Gene Synthesis