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Co-delivery of Cas9 mRNA and guide RNAs edits hepatitis B virus episomal and integration DNA in mouse and tree shrew models

Authors: Junzhu Yi, Xinlin Lei, Fangteng Guo, Qiubing Chen, Xueyong Chen, Kaitao Zhao, Chengliang Zhu, Xiaoming Cheng, Jiangwei Lin, Hao Yin, Yuchen Xia

Journal: Antiviral research

PubMed ID: 37142191

Doi: 10.1016/j.antiviral.2023.105618

Products & Services: CRISPR RNAs/Cas9 Proteins(INACTIVE)

Immunogenic SARS-CoV-2 S and N Protein Peptide and Cytokine Combinations as Biomarkers for Early Prediction of Fatal COVID-19

Authors: Ekaterina Martynova , Shaimaa Hamza , Maria Markelova , Ekaterina Garanina , Yuriy Davidyuk , Venera Shakirova , Neha Kaushal , Manoj Baranwal , Robert J Stott-Marshall , Toshana L Foster , Albert Rizvanov , Svetlana Khaiboullina

Journal: Front Immunol .

PubMed ID: 35386707

Doi: 10.3389/fimmu.2022.830715

Products & Services: Peptide Synthesis

In vitro reconstitution of SARS-CoV-2 Nsp1-induced mRNA cleavage reveals the key roles of the N-terminal domain of Nsp1 and the RRM domain of eIF3g

Authors: Irina S. Abaeva, Yani Arhab, Anna Miscicka, Christopher U.T. Hellen, and Tatyana V. Pestova

Journal: bioRxiv .

PubMed ID: 37292671

Doi: 10.1101/gad.350829.123

Products & Services: Gene Synthesis

Fusion of the molecular adjuvant C3d to cleavage-independent native-like HIV-1 Env trimers improves the elicited antibody response

Authors: Shridhar Bale, Lifei Yang, Mehrdad Alirezaei, Richard Wilson, Takayuki Ota, Esmeralda D Doyle, Christopher A Cottrell, Javier Guenaga, Karen Tran, Wenjuan Li, Leonidas Stamatatos, David Nemazee, Andrew B Ward, Richard T Wyatt

Journal: Front Immunol

PubMed ID: 37283743

Doi: 10.3389/fimmu.2023.1180959

Products & Services: Protein and Antibody Isolation

CFTR and dystrophin encoding plasmids carrying both luciferase reporter gene, nuclear import specific sequences and triple helix sites

Authors: Delphine Maze, Caroline Girardin, Nathalie Benz, Tristan Montier, Chantal Pichon, Patrick Midoux

Journal: Plasmid

PubMed ID: 37207938

Doi: 10.1016/j.plasmid.2023.102686

Products & Services: Protein and Antibody Isolation

Antibody blockade of Jagged1 attenuates choroidal neovascularization

Authors: Torleif Tollefsrud Gjølberg, Jonas Aakre Wik, Hanna Johannessen, Stig Krüger, Nicola Bassi, Panagiotis F Christopoulos, Malin Bern, Stian Foss, Goran Petrovski, Morten C Moe, Guttorm Haraldsen, Johanna Hol Fosse, Bjørn Steen Skålhegg, Jan Terje Andersen, Eirik Sundlisæter

Journal: Nat Commun

PubMed ID: 37253747

Doi: 10.1038/s41467-023-38563-w

Products & Services: Protein and Antibody Isolation

Leveraging a Structural Blueprint to Rationally Engineer the Rieske Oxygenase TsaM

Authors: Jiayi Tian, Alejandro Arcadio Garcia, Patrick H Donnan, Jennifer Bridwell-Rabb

Journal: Biochemistry

PubMed ID: 37188334

Doi: 10.1021/acs.biochem.3c00150

Products & Services: Protein and Antibody Isolation

Antigen-Induced IL-1RA Production Discriminates Active and Latent Tuberculosis Infection

Authors: Cesar Sanchez, Luis Jaramillo-Valverde, Silvia Capristano, Gilmer Solis, Alonso Soto, Julio Valdivia-Silva, Julio A Poterico, Heinner Guio

Journal: Microorganisms

PubMed ID: 37374887

Doi: 10.3390/microorganisms11061385

Products & Services: Peptide Synthesis

Small heterodimer partner interacting leucine zipper protein (SMILE) ameliorates autoimmune arthritis via AMPK signaling pathway and the regulation of B cell activation

Authors: JooYeon Jhun, Jeonghyeon Moon, Ji Ye Kwon, Keun-Hyung Cho, Seang Yoon Lee, Hyun Sik Na, Mi-La Cho, Jun-Ki Min

Journal: Cell Commun Signal

PubMed ID: 37143079

Doi: 10.1186/s12964-023-01054-y

Products & Services: Codon Optimization

Connexin 37 sequestering of activated-ERK in the cytoplasm promotes p27-mediated endothelial cell cycle arrest

Authors: Bipul R Acharya, Jennifer S Fang, Erin D Jeffery, Nicholas W Chavkin, Gael Genet, Hema Vasavada, Elizabeth A Nelson, Gloria M Sheynkman, Martin J Humphries, Karen K Hirschi

Journal: Life Sci Alliance

PubMed ID: 37197981

Doi: 10.26508/lsa.202201685

Products & Services: Molecular Biology Reagents