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Multiple myeloma associated long non-coding RNA PLUM confers chemoresistance by enhancing PRC2 mediated UPR pathway activation

Authors: Kamalakshi Deka, Jean-Michel Carter, Akash Bahai, Daniel Aron Ang, Nicholas Sim, Hooi Yan Chong, Guan Hwee Bernard Lee, Suet Mien Tan, Wee Joo Chng, Dennis Kappei, Yinghui Li

Journal: Nature Communications

PubMed ID: 40890111

Doi: 10.1038/s41467-025-63256-x.

Products & Services: Gene Services

Structural insights into proprotein convertase activation facilitate the engineering of highly specific furin inhibitors

Authors: Rupert Klaushofer, Konstantin Bloch, Luisa Susanna Eder, Simone Marzaro, Mario Schubert, Eva Böttcher-Friebertshäuser, Hans Brandstetter, Sven O Dahms

Journal: Nature Communications

PubMed ID: 40897699

Doi: 10.1038/s41467-025-63479-y.

Ultrastrong Staphylococcus aureus adhesion to human skin: Calcium as a key regulator of noncovalent interactions

Authors: Constance Chantraine, Priscila S F C Gomes, Marion Mathelié-Guinlet, Diego E B Gomes, Zhiyong Zheng, Julianne Clowry, Mary B Turley, Alan D Irvine, Joan A Geoghegan, Rafael C Bernardi, Yves F Dufrêne

Journal: SCIENCE ADVANCES

PubMed ID: 40901964

Doi: 10.1126/sciadv.adu7457

The kinetics of nsp7-11 polyprotein processing and impact on complexation with nsp16 among human coronaviruses

Authors: Kira Schamoni-Kast, Boris Krichel, Tomislav Damjanović, Fatema-Aqila Said, Thomas Kierspel, Sibel Toker, Charlotte Uetrecht

Journal: Nature Communications

PubMed ID: 40925907

Doi: 10.1038/s41467-025-61554-y.

Products & Services: Gene Services

UHRF1 Controls the Timing of RAD51 Removal During DNA Damage Repair Through Suppressing RFWD3

Authors: Guangxue Liu, Kaiyan Huang, Shiyao Liu, Ziyu Sheng, Pumin Zhang

Journal: Advanced Science

PubMed ID: 40940676

Doi: 10.1002/advs.202509901

M2e peptide libraries were synthesized on the basis of the M2e-CS peptide, N-SLLTEVETPIRNEWGCRCNDSSD, and purchased from GenScript.

Authors: Teha Kim, Lynn Bimler, Sydney L Ronzulli, Amber Y Song, Scott K Johnson, Cheryl A Jones, S Mark Tompkins, Silke Paust

Journal: SCIENCE ADVANCES

PubMed ID: 40929256

Doi: 10.1126/sciadv.adx3505

Products & Services: Peptide Services

Mining the CD4 antigen repertoire for next-generation tuberculosis vaccines

Authors: Samuel J Vidal, Ninaad Lasrado, Lisa H Tostanoski, Jayeshbhai Chaudhari, Esther R Mbiwan, Ganad D Neka, Ellis A Strutton, Alejandro A Espinosa Perez, Daniel Sellers, Julia Barrett, Michelle Lifton, Shoko Wakabayashi, Behnaz Eshaghi, Erica N Borducchi, Malika Aid, Wenjun Li, Thomas J Scriba, Ana Jaklenec, Robert Langer, Dan H Barouch

Journal: Cell

PubMed ID: 40957415

Doi: 10.1016/j.cell.2025.08.027

Products & Services: Peptide Services

Molecular exaptation by the integrin αI domain

Authors: Jeremy A Hollis, Matthew C Chan, Harmit S Malik, Melody G Campbell

Journal: SCIENCE ADVANCES

PubMed ID: 40929264

Doi: 10.1126/sciadv.adx9567

Products & Services: Gene Services

Intrinsically disordered region of Clr4/Suv39 regulates its enzymatic activity and ensures heterochromatin spreading

Authors: Rinko Nakamura, Aki Hayashi, Reiko Nakagawa, Yuriko Yoshimura, Naoki Horikoshi, Hitoshi Kurumizaka, Jun-Ichi Nakayama

Journal: Nucleic Acids Research

PubMed ID: 40923761

Doi: 10.1093/nar/gkaf878

Computational design of potent and selective binders of BAK and BAX

Authors: Stephanie Berger, Erinna F Lee, Tiffany J Harris, Sharon Tran, Asim K Bera, Lauren Arguinchona, Alex Kang, Banumathi Sankaran, Sila Kasapgil, Michelle S Miller, Sean Smyth, Mariam Lutfi, Rachel T Uren, Ruth M Kluck, Peter M Colman, Walter D Fairlie, Peter E Czabotar, David Baker, Richard W Birkinshaw

Journal: SCIENCE ADVANCES

PubMed ID: 40911686

Doi: 10.1126/sciadv.adt4170