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Development of allosteric and selective CDK2 inhibitors for contraception with negative cooperativity to cyclin binding

Authors: Erik B Faber, Luxin Sun, Jian Tang, Emily Roberts, Sornakala Ganeshkumar, Nan Wang, Damien Rasmussen, Abir Majumdar, Laura E Hirsch, Kristen John, An Yang, Hira Khalid, Jon E Hawkinson, Nicholas M Levinson, Vargheese Chennathukuzhi, Daniel A Harki, Ernst Schönbrunn, Gunda I Georg

Journal: Nat Commun

PubMed ID: 37270540

Doi: 10.1038/s41467-023-38732-x

Products & Services: Molecular Biology Reagents

Grafting Rhodobacter sphaeroides with red algae Rubisco to accelerate catalysis and plant growth

Authors: Yu Zhou, Laura H Gunn, Rosemary Birch, Inger Andersson, Spencer M Whitney

Journal: Nat Plants

PubMed ID: 37291398

Doi: 10.1038/s41477-023-01436-7

Products & Services: Molecular Biology Reagents

Systematic Mining and Evaluation of the Sesquiterpene Skeletons as High Energy Aviation Fuel Molecules

Authors: Yanglei Huang, Ziling Ye, Xiukun Wan, Ge Yao, Jingyu Duan, Jiajia Liu, Mingdong Yao, Xiang Sun, Zixin Deng, Kun Shen, Hui Jiang, Tiangang Liu

Journal: Adv Sci (Weinh)

PubMed ID: 37271925

Doi: 10.1002/advs.202300889

Products & Services: Molecular Biology Reagents

Glutamine synthetase (GS) knockout (KO) using CRISPR/Cpf1 diversely enhances selection efficiency of CHO cells expressing therapeutic antibodies

Authors: Witsanu Srila, Martina Baumann, Markus Riedl, Kuntalee Rangnoi, Nicole Borth, Montarop Yamabhai

Journal: Sci Rep

PubMed ID: 37380701

Doi: 10.1038/s41598-023-37288-6

Products & Services: Protein and Antibody Isolation

Structural insights into regulation of the PEAK3 pseudokinase scaffold by 14-3-3

Authors: Hayarpi Torosyan, Michael D Paul, Antoine Forget, Megan Lo, Devan Diwanji, Krzysztof Pawłowski, Nevan J Krogan, Natalia Jura, Kliment A Verba

Journal: Nat Commun

PubMed ID: 37336883

Doi: 10.1038/s41467-023-38864-0

Products & Services: Gene Synthesis

An Inferred Ancestral CotA Laccase with Improved Expression and Kinetic Efficiency

Authors: Lei Lei, Lijun Zhao, Yiqia Hou, Chen Yue, Pulin Liu, Yanli Zheng, Wenfang Peng, Jiangke Yang

Journal: Int J Mol Sci

PubMed ID: 37446078

Doi: 10.3390/ijms241310901

Products & Services: Recombinant Proteins

Increasing sensitivity of antibody-antigen interactions using photo-cross-linking

Authors: Alba Torrents de la Peña, Leigh M Sewall, Rebeca de Paiva Froes Rocha, Abigail M Jackson, Payal P Pratap, Sandhya Bangaru, Christopher A Cottrell, Subhasis Mohanty, Albert C Shaw, Andrew B Ward

Journal: Cell Rep Methods

PubMed ID: 37426749

Doi: 10.1016/j.crmeth.2023.100509

Products & Services: Protein and Antibody Isolation

Author Correction: RNA conformational propensities determine cellular activity

Authors: Megan L Ken, Rohit Roy, Ainan Geng, Laura R Ganser, Akanksha Manghrani, Bryan R Cullen, Ursula Schulze-Gahmen, Daniel Herschlag, Hashim M Al-Hashimi

Journal: Nature

PubMed ID: 37296211

Doi: 10.1038/s41586-023-06286-z

Products & Services: Peptide Synthesis

Assimilatory sulfate reduction in the marine methanogen Methanothermococcus thermolithotrophicus

Authors: Marion Jespersen, Tristan Wagner

Journal: Nat Microbiol

PubMed ID: 37277534

Doi: 10.1038/s41564-023-01398-8

Products & Services: DNA Sequencing

Spatiotemporal and global profiling of DNA–protein interactions enables discovery of low-affinity transcription factors

Authors: An-Di Guo , Ke-Nian Yan, Hao Hu , Linhui Zhai , Teng-Fei Hu , Haixia Su , Yijia Chi , Jinyin Zha , Yechun Xu , Dongxin Zhao , Xiaojie Lu , Yong-Jiang Xu , Jian Zhang , Minjia Tan, Xiao-Hua Chen

Journal: Nat Chem .

PubMed ID: 37106095

Doi: 10.1038/s41557-023-01196-z

Products & Services: Peptide Synthesis