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Broad Sarbecovirus Neutralizing Antibodies Obtained by Computational Design and Synthetic Library Screening

Authors: Xuehua Yang, Huarui Duan, Xiuying Liu, Xinhui Zhang, Shengnan Pan, Fangyuan Zhang, Peixiang Gao, Bo Liu, Jian Yang, Xiaojing Chi, Wei Yang

Journal: J Virol

PubMed ID: 37367229

Doi: 10.1128/jvi.00610-23

Products & Services: Protein and Antibody Isolation

Inhibition of chitin deacetylases to attenuate plant fungal diseases

Authors: Lin Liu, Yeqiang Xia, Yingchen Li, Yong Zhou, Xiaofeng Su, Xiaojing Yan, Yan Wang, Wende Liu, Hongmei Cheng, Yuanchao Wang, Qing Yang

Journal: Nat Commun

PubMed ID: 37385996

Doi: 10.1038/s41467-023-39562-7

Products & Services: Gene Synthesis

Revealing the impact of CD70 expression on the manufacture and functions of CAR-70 T-cells based on single-cell transcriptomics

Authors: Jiali Cheng, Yuyan Zhao, Hui Hu, Ling Tang, Yuhao Zeng, Xinyue Deng, Shengnan Ding, An-Yuan Guo, Qing Li, Xiaojian Zhu

Journal: Cancer Immunol Immunother

PubMed ID: 37382633

Doi: 10.1007/s00262-023-03475-7

Products & Services: Protein and Antibody Isolation

Structural insights into mechanisms of Argonaute protein-associated NADase activation in bacterial immunity

Authors: Xiaoshen Wang, Xuzichao Li, Guimei Yu, Lingling Zhang, Chendi Zhang, Yong Wang, Fumeng Liao, Yanan Wen, Hang Yin, Xiang Liu, Yong Wei, Zhuang Li, Zengqin Deng, Heng Zhang

Journal: Cell Res

PubMed ID: 37311833

Doi: 10.1038/s41422-023-00839-7

Generation of host-directed and virus-specific antivirals using targeted protein degradation promoted by small molecules and viral RNA mimics

Authors: Nan Zhao, Jessica Sook Yuin Ho, Fanye Meng, Simin Zheng, Andrew P Kurland, Lu Tian, Martha Rea-Moreno, Xiangyang Song, Ji-Seon Seo, H Ümit Kaniskan, Aartjan J W Te Velthuis, Domenico Tortorella, Ya-Wen Chen, Jeffrey R Johnson, Jian Jin, Ivan Marazzi

Journal: Cell Host Microbe

PubMed ID: 37339625

Doi: 10.1016/j.chom.2023.05.030

Products & Services: Protein Electrophoresis and Western

Plasmodium GPI-anchored micronemal antigen is essential for parasite transmission through the mosquito host

Authors: Charlie Jennison, Janna M Armstrong, Dorender A Dankwa, Nina Hertoghs, Sudhir Kumar, Biley A Abatiyow, Myo Naung, Nana K Minkah, Kristian E Swearingen, Robert Moritz, Alyssa E Barry, Stefan H I Kappe, Ashley M Vaughan

Journal: Mol Microbiol

PubMed ID: 37314965

Doi: 10.1111/mmi.15078

Products & Services: Molecular Biology Reagents

SARS-CoV-2 S1 Subunit Booster Vaccination Elicits Robust Humoral Immune Responses in Aged Mice

Authors: Eun Kim, Muhammad S Khan , Alessandro Ferrari , Shaohua Huang , Josè C Sammartino, Elena Percivalle, Thomas W Kenniston, Irene Cassaniti , Fausto Baldanti, Andrea Gambotto

Journal: Microbiology Spectrum

PubMed ID: 37162333

Doi: PMC10269910

Products & Services: Codon Optimization

Optogenetic inhibition of Gα signalling alters and regulates circuit functionality and early circuit formation

Authors: Jayde Lockyer, Andrew Reading, Silvia Vicenzi, Caroline Delandre, Owen Marshall, Robert Gasperini, Lisa Foa, John Y Lin

Journal: biorxiv

PubMed ID: 37214843

Doi: 10.1101/2023.05.06.539674

Products & Services: Protein and Antibody Isolation

Leptospiral imelysin (LIC_10713) is secretory, immunogenic and binds to laminin, fibronectin, and collagen IV

Authors: Abhijit Sarma, Dhandapani Gunasekaran, Homen Phukan, Akhil Baby, Suneetha Hariharan, Arun Kumar De, Debasis Bhattacharya, Sankar Natesan, Jebasingh Tennyson, Madathiparambil Gopalakrishnan Madanan

Journal: Appl Microbiol Biotechnol

PubMed ID: 37227474

Doi: 10.1007/s00253-023-12573-6

Products & Services: Molecular Biology Reagents

CDK12 and Integrator-PP2A complex modulates LEO1 phosphorylation for processive transcription elongation

Authors: Min Qiu, Zhinang Yin, Honghong Wang, Lingyu Lei, Conghui Li, Yali Cui, Rong Dai, Peiyuan Yang, Ying Xiang, Qiuzi Li, Junhui Lv, Zhuang Hu, Min Chen, Hai-Bing Zhou, Pingping Fang, Ruijing Xiao, Kaiwei Liang

Journal: Sci Adv

PubMed ID: 37205756

Doi: 10.1126/sciadv.adf8698

Products & Services: Molecular Biology Reagents