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Atomic model for core modifying region of human fatty acid synthase in complex with Denifanstat

Authors: S M Naimul Hasan, Jennifer W Lou, Alexander F A Keszei, David L Dai, Mohammad T Mazhab-Jafari

Journal: Nat Commun

PubMed ID: 37308485

Doi: 10.1038/s41467-023-39266-y

Products & Services: Plasmid DNA Preparation

Varicella-zoster virus proteome-wide T-cell screening demonstrates low prevalence of virus-specific CD8 T-cells in latently infected human trigeminal ganglia

Authors: Michiel van Gent, Werner J D Ouwendijk, Victoria L Campbell, Kerry J Laing, Georges M G M Verjans, David M Koelle

Journal: J Neuroinflammation

PubMed ID: 37308917

Doi: 10.1186/s12974-023-02820-y

Products & Services: Peptide Synthesis

Improved extracellular vesicle-based mRNA delivery for familial hypercholesterolemia treatment

Authors: Zheng Yang, Panpan Ji, Zhelong Li, Rongxin Zhang, Mengying Wei, Yang Yang, Lijun Yuan, Yan Han, Guodong Yang

Journal: Theranostics

PubMed ID: 37351166

Doi: 10.7150/thno.82873

Products & Services: Recombinant Antibody Expression

Engineering Scheffersomyces segobiensis for palmitoleic acid-rich lipid production

Authors: Xiujuan Qian, Huirui Lei, Xinhai Zhou, Lili Zhang, Wenxing Cui, Jie Zhou, Fengxue Xin, Weiliang Dong, Min Jiang, Katrin Ochsenreither

Journal: Microb Biotechnol

PubMed ID: 37351580

Doi: 10.1111/1751-7915.14301

Products & Services: Codon Optimization

Engineering B cells with customized therapeutic responses using a synthetic circuit

Authors: Audrey Page, Marie Delles, Didier Nègre, Caroline Costa, Floriane Fusil, François-Loïc Cosset

Journal: Mol Ther Nucleic Acids

PubMed ID: 37359346

Doi: 10.1016/j.omtn.2023.05.024

Products & Services: PCR Cloning and Subcloning

Structural mechanism of intracellular autoregulation of zinc uptake in ZIP transporters

Authors: Changxu Pang, Jin Chai, Ping Zhu, John Shanklin, Qun Liu

Journal: Nat Commun

PubMed ID: 37296139

Doi: 10.1038/s41467-023-39010-6

Products & Services: Gene Synthesis

Scribble mis-localization induces adaptive resistance to KRAS G12C inhibitors through feedback activation of MAPK signaling mediated by YAP-induced MRAS

Authors: Yuta Adachi, Ryo Kimura, Kentaro Hirade, Shogo Yanase, Yuki Nishioka, Natsumi Kasuga, Rui Yamaguchi, Hiromichi Ebi

Journal: Nat Cancer

PubMed ID: 37277529

Doi: 10.1038/s43018-023-00575-2

Products & Services: PCR Cloning and Subcloning

GRT-R910: a self-amplifying mRNA SARS-CoV-2 vaccine boosts immunity for ≥6 months in previously-vaccinated older adults

Authors: Christine D Palmer, Ciaran D Scallan, Lauren D Kraemer Tardif, Melissa A Kachura, Amy R Rappaport, Daniel O Koralek, Alison Uriel, Leonid Gitlin, Joshua Klein, Matthew J Davis, Harshni Venkatraman, Meghan G Hart, Jason R Jaroslavsky, Sonia Kounlavouth, Martina Marrali, Charmaine N Nganje, Kyounghwa Bae, Tiffany Yan, Katharyn Leodones, Milana Egorova, Sue-Jean Hong, Jenchun Kuan, Silvia Grappi, Pedro Garbes, Karin Jooss, Andrew Ustianowski

Journal: Nat Commun

PubMed ID: 37280238

Doi: 10.1038/s41467-023-39053-9

Products & Services: Peptide Synthesis

Assessing the Feasibility of Employing a Combination of a Bacteriophage-Derived Endolysin and Spore Germinants to Treat Relapsing Infection

Authors: Khalid Alyahya, Les Baillie

Journal: Microorganisms

PubMed ID: 37512824

Doi: 10.3390/microorganisms11071651

Products & Services: Custom Vector Construction

Expression and characterization of recombinant IL-1Ra in Aspergillus oryzae as a system

Authors: Lena Mahmoudi Azar, Elif Karaman, Burcu Beyaz, Işılay Göktan, Alp Ertunga Eyüpoğlu, Seda Kizilel, Batu Erman, Ahmet Gül, Serdar Uysal

Journal: BMC Biotechnol

PubMed ID: 37340430

Doi: 10.1186/s12896-023-00785-7

Products & Services: Gene Synthesis