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Optimization of mammalian expression vector by cis-regulatory element combinations

Authors: Lu-Yu Zhou, Shuang Zhang, Li-Yun Li, Guo-Yu Yang, Lei Zeng

Journal: Mol Genet Genomics

PubMed ID: 37318628

Doi: 10.1007/s00438-023-02042-0

Products & Services: Gene Synthesis

miR‑124 inhibits cardiomyocyte apoptosis in myocardial ischaemia‑reperfusion injury by activating mitochondrial calcium uniporter regulator 1

Authors: Linlin Guo, Chaoying Liu, Chunyan Jiang, Yanhan Dong, Lynn Htet Htet Aung, Han Ding, Yanyan Gao

Journal: Mol Med Rep

PubMed ID: 37326122

Doi: 10.3892/mmr.2023.13031

Products & Services: Molecular Biology Reagents

Enzyme assembly on nanoparticle scaffolds enhances cofactor recycling and improves coupled reaction kinetics

Authors: Joyce C Breger, Ellen R Goldman, Kimihiro Susumu, Eunkeu Oh, Christopher M Green, Shelby L Hooe, Meghna Thakur, Igor L Medintz, Gregory A Ellis

Journal: Nanoscale

PubMed ID: 37272342

Doi: 10.1039/d3nr00729d

Products & Services: Protein and Antibody Isolation

In Vitro and In Vivo Efficacy of a Stroma-Targeted, Tumor Microenvironment Responsive Oncolytic Adenovirus in Different Preclinical Models of Cancer

Authors: Ana Alfano, Eduardo G A Cafferata, Mariela Gangemi, Alejandro Nicola Candia, Cristian M Malnero, Ismael Bermudez, Mauricio Vargas Lopez, Gregorio David Ríos, Cecilia Rotondaro, Nicasio Cuneo, David T Curiel, Osvaldo L Podhajcer, Maria Veronica Lopez

Journal: Int J Mol Sci

PubMed ID: 37373140

Doi: 10.3390/ijms24129992

Products & Services: Protein and Antibody Isolation

Heme catabolism mediated by heme oxygenase in uninfected interstitial cells enables efficient symbiotic nitrogen fixation in Lotus japonicus nodules

Authors: Yu Zhou, Longlong Wang, Maria Carmen Rubio, Carmen Pérez-Rontomé, Yumiao Zhou, Yongmei Qi, Tao Tian, Weiqing Zhang, Qiuling Fan, Manuel Becana, Deqiang Duanmu

Journal: New Phytol

PubMed ID: 37329247

Doi: 10.1111/nph.19074

Products & Services: Protein and Antibody Isolation

NeuroMabSeq: high volume acquisition, processing, and curation of hybridoma sequences and their use in generating recombinant monoclonal antibodies and scFvs for neuroscience research

Authors: Keith G Mitchell, Belvin Gong, Samuel S Hunter, Diana Burkart-Waco, Clara E Gavira-O'Neill, Kayla M Templeton, Madeline E Goethel, Malgorzata Bzymek, Leah M MacNiven, Karl D Murray, Matthew L Settles, Lutz Froenicke, James S Trimmer

Journal: biorxiv

PubMed ID: 37425915

Doi: 10.1101/2023.06.28.546392

Products & Services: Protein and Antibody Isolation

N-terminal intrinsic disorder is an ancestral feature of Gγ subunits that influences the balance between different Gβγ signaling axes in yeast

Authors: Xinya Su, Yui Tik Pang, Wei Li, J C Gumbart, Joshua Kelley, Matthew Torres

Journal: J Biol Chem

PubMed ID: 37354971

Doi: 10.1016/j.jbc.2023.104947

Products & Services: Peptide Synthesis

Exploration of T cell immune responses by expression of a dominant-negative SHP1 and SHP2

Authors: Julia Taylor, Anna Bulek, Isaac Gannon, Mathew Robson, Evangelia Kokalaki, Thomas Grothier, Callum McKenzie, Mohamed El-Kholy, Maria Stavrou, Charlotte Traynor-White, Wen Chean Lim, Panagiota Panagiotou, Saket Srivastava, Vania Baldan, James Sillibourne, Mathieu Ferrari, Martin Pule, Simon Thomas

Journal: Front Immunol

PubMed ID: 37334382

Doi: 10.3389/fimmu.2023.1119350

Products & Services: Peptide Synthesis

A Highly-Parallelized and Low-Sample-Size chip for Simultaneous Detectison of Protein and Nucleic Acid Biomarkers in Hepatocellular Carcinoma

Authors: Yingxue Li, Qi Xu, Wei Zhang, Qi Yang, Zhen Guo, Chuanyu Li, Zhiqi Zhang, Qiongzhu Dong, Haoting Sun, Changsong Zhang, Chao Li, Jia Yao, Jinze Li, Lunxiu Qin, Lianqun Zhou

Journal: Sensors and Actuators B: Chemical

Doi: 10.1016/j.snb.2023.134112

Products & Services: Antibody Services

Production of the antidepressant orcinol glucoside in Yarrowia lipolytica with yields over 6,400-fold higher than plant extraction

Authors: Bihuan Chen , Xiaonan Liu , Yina Wang , Jie Bai , Xiangyu Liu , Guisheng Xiang , Wei Liu , Xiaoxi Zhu , Jian Cheng , Lina Lu , Guanghui Zhang , Ge Zhang, Zongjie Dai, Shuhui Zi , Shengchao Yang, Huifeng Jiang

Journal: PLoS Biol .

PubMed ID: 37279234

Doi: 10.1371/journal.pbio.3002131

Products & Services: Codon Optimization