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页码: 33/5154 每页显示数量

Evolutionary insights into the stereoselectivity of imine reductases based on ancestral sequence reconstruction

Authors: Xin-Xin Zhu, Wen-Qing Zheng, Zi-Wei Xia, Xin-Ru Chen, Tian Jin, Xu-Wei Ding, Fei-Fei Chen, Qi Chen, Jian-He Xu, Xu-Dong Kong, Gao-Wei Zheng

Journal: Nat Commun

PubMed ID: 39609402

Doi: 10.1038/s41467-024-54613-3

Products & Services: Plasmid DNA Preparation

Interactions established by isoform-specific TrkB-T1 sequences govern inflammatory response and neurotoxicity in stroke

Authors: Lola Ugalde-Triviño, Gonzalo S. Tejeda, Gema M. Esteban-Ortega, Margarita Díaz-Guerra

Journal: bioRxiv

Doi: doi.org/10.1101/2024.11.13.623346

Products & Services: Catalog Peptides

Both chebulagic acid and punicalagin inhibit respiratory syncytial virus entry via multi-targeting glycoprotein and fusion protein

Authors: Yingcai Xiong , Keyu Tao , Tao Li , Yinghui Zhou , Zhaowei Zhang , Weiying Ou , Zhao Wang , Shouchuan Wang , Yayi Hou , Peng Cao , Jianjian Ji

Journal: J Virol

PubMed ID: 39508604

Doi: 10.1128/jvi.01536-24

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Engineered mRNAs with stable structures minimize double-stranded RNA formation and increase protein expression

Authors: Qianshan Qin , Huayuan Yan , Weixiang Gao , Ruyin Cao , Guopeng Liu , Xiaojing Zhang , Niangang Wang , Wenjie Zuo , Lei Yuan , Peng Gao , Qi Liu

Journal: J Mol Biol

PubMed ID: 39427983

Doi: 10.1016/J.JMB.2024.168822

Products & Services: Gene Synthesis

Spatial organization of PI3K-PI(3,4,5)P3-AKT signaling by focal adhesions

Authors: Jing Wang , Zhengyang An , Zhongsheng Wu , Wei Zhou , Pengyu Sun , Piyu Wu , Song Dang , Rui Xue , Xue Bai , Yongtao Du , Rongmei Chen , Wenxu Wang , Pei Huang , Sin Man Lam , Youwei Ai , Suling Liu , Guanghou Shui , Zhe Zhang , Zheng Liu , Jianyong Huang , Xiaohong Fang , Kangmin He

Journal: Mol Cell

PubMed ID: 39488211

Doi: 10.1016/j.molcel.2024.10.010

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RAD18-catalysed formation of ubiquitination intermediate mimic of proliferating cell nuclear antigen PCNA

Authors: Liying Zhang, Zhiheng Deng, Yunxiang Du, Ziyu Xu, Tianyi Zhang, Zebin Tong, Huasong Ai, Lu-Jun Liang, Lei Liu

Journal: Bioorg Med Chem

PubMed ID: 39580855

Doi: 10.1016/j.bmc.2024.118016

Products & Services: Gene Synthesis Proteins, Expression, Isolation and Analysis

A high-performance protein preparation approach in a single column-free step

Authors: Yuan Huang, Yuanyuan Zhang, Xiaofeng Yang, Zhanglin Lin

Journal: Trends Biotechnol

PubMed ID: 39537535

Doi: 10.1016/j.tibtech.2024.10.008

Products & Services: Proteins, Expression, Isolation and Analysis

SARS-CoV-2 N protein coordinates viral particle assembly through multiple domains

Authors: Yuewen Han 1, Haiwu Zhou 1, Cong Liu 1, Weiwei Wang 1, Yali Qin 2, Mingzhou Chen

Journal: Journal of Virology

PubMed ID: 39412257

Doi: 10.1128/jvi.01036-24

Products & Services: Plasmids for SARS-CoV-2 Detection and Research Gene Synthesis

Single-Dose Physically Cross-Linked Hyaluronic Acid and Lipid Hybrid Nanoparticles Containing Cyclic Guanosine Monophosphate-Adenosine Monophosphate Eliminate Established Tumors

Authors: Jinchao Yu , Xinyan Li , Junyao Li , Nan Sun , Peng Cheng , Jiayi Huang , Sai Li , Rui Kuai

Journal: ACS Nano

PubMed ID: 39418110

Doi: 10.1021/acsnano.4c10673

Products & Services: Recombinant Proteins

Caspase-2 is a condensate-mediated deubiquitinase in protein quality control

Authors: Yingwei Ge , Lijie Zhou, Yesheng Fu , Lijuan He, Yi Chen , Dingchang Li , Yuping Xie , Jun Yang , Haitao Wu, Hongmiao Dai , Zhiqiang Peng , Yong Zhang , Shaoqiong Yi , Bo Wu 1, Xin Zhang, Yangjun Zhang , Wantao Ying 1, Chun-Ping Cui , Cui Hua Liu , Lingqiang Zhang

Journal: Nature Cell Biology

PubMed ID: 39482354

Doi: 10.1038/s41556-024-01522-8

Products & Services: Mutagenesis Services