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A conserved motif in the disordered linker of human MLH1 is vital for DNA mismatch repair and its function is diminished by a cancer family mutation

Authors: Karla Wolf, Jan Kosinski, Toby J Gibson, Nicole Wesch, Volker Dötsch, Maurizio Genuardi, Emanuela Lucci Cordisco, Stefan Zeuzem, Angela Brieger, Guido Plotz

Journal: Nucleic Acids Res

PubMed ID: 37224528

Doi: 10.1093/nar/gkad418

Products & Services: Peptide Synthesis

Prediction of cooperative homeodomain DNA binding sites from high-throughput-SELEX data

Authors: Brittany Cain, Jordan Webb, Zhenyu Yuan, David Cheung, Hee-Woong Lim, Rhett A Kovall, Matthew T Weirauch, Brian Gebelein

Journal: Nucleic Acids Res

PubMed ID: 37114997

Doi: 10.1093/nar/gkad318

Products & Services: Plasmid DNA Preparation

A Novel Bispecific Antibody for EpCAM-Directed Inhibition of the CD73/Adenosine Immune Checkpoint in Ovarian Cancer

Authors: Emily Maria Ploeg, Isabel Britsch, Anne Paulien van Wijngaarden, Xiurong Ke, Mark Alexander Johannes Martinus Hendriks, Douwe Freerk Samplonius, Wijnand Helfrich

Journal: Cancers (Basel)

PubMed ID: 37509310

Doi: 10.3390/cancers15143651

Products & Services: Gene Synthesis

Intratumoral immune triads are required for adoptive T cell therapy-mediated elimination of solid tumors

Authors: Gabriel Espinosa-Carrasco, Aurora Scrivo, Paul Zumbo, Asim Dave, Doron Betel, Matthew Hellmann, Bryan M Burt, Hyun-Sung Lee, Andrea Schietinger

Journal: biorxiv

PubMed ID: 37461721

Doi: 10.1101/2023.07.03.547423

Products & Services: Peptide Synthesis

Establishment and characterization of an SV40 immortalized chicken intestinal epithelial cell line

Authors: Federico Ghiselli, Martina Felici, Andrea Piva, Ester Grilli

Journal: Poult Sci

PubMed ID: 37517361

Doi: 10.1016/j.psj.2023.102864

Products & Services: Protein and Antibody Isolation

Probing Substrate Transport Effects on Enzymatic Hydrogen Catalysis: An Alternative Proton Transfer Pathway in Putatively Sensory [FeFe] Hydrogenase

Authors: Princess R Cabotaje, Kaija Walter, Afridi Zamader, Ping Huang, Felix Ho, Henrik Land, Moritz Senger, Gustav Berggren

Journal: ACS Catal

PubMed ID: 37560193

Doi: 10.1021/acscatal.3c02314

Products & Services: Protein and Antibody Isolation

Protein oxidation increases SAMHD1 binding ssDNA via its regulatory site

Authors: Theresa L Simermeyer, Stephanie Batalis, LeAnn C Rogers, Owen J Zalesak, Thomas Hollis

Journal: Nucleic Acids Res

PubMed ID: 37246644

Doi: 10.1093/nar/gkad447

Products & Services: Protein and Antibody Isolation

Feasibility and Safety of Personalized, Multi-Target, Adoptive Cell Therapy (IMA101): First-in-Human Clinical Trial in Patients with Advanced Metastatic Cancer

Authors: Apostolia M Tsimberidou, Kerstin Guenther, Borje S Andersson, Regina Mendrzyk, Amir Alpert, Claudia Wagner, Anna Nowak, Katrin Aslan, Arun Satelli, Fabian Richter, Sabrina Kuttruff-Coqui, Oliver Schoor, Jens Fritsche, Zoe Coughlin, Ali S Mohamed, Kerry Sieger, Becky Norris, Rita Ort, Jennifer Beck, Henry Hiep Vo, Franziska Hoffgaard, Manuel Ruh, Linus Backert, Ignacio I Wistuba, David Fuhrmann, Nuhad K Ibrahim, Van Karlyle Morris, Bryan K Kee, Daniel M Halperin, Graciela M Nogueras-Gonzalez, Partow Kebriaei, Elizabeth J Shpall, David Vining, Patrick Hwu, Harpreet Singh, Carsten Reinhardt, Cedrik M Britten, Norbert Hilf, Toni Weinschenk, Dominik Maurer, Steffen Walter

Journal: Cancer Immunol Res

PubMed ID: 37172100

Doi: 10.1158/2326-6066.CIR-22-0444

Products & Services: Protein and Antibody Isolation

Antibody binding of amyloid beta peptide epimers/isomers and ramifications for immunotherapies and drug development

Authors: Elizabeth R Readel, Arzoo Patel, Joshua I Putman, Siqi Du, Daniel W Armstrong

Journal: Sci Rep

PubMed ID: 37524807

Doi: 10.1038/s41598-023-38788-1

Products & Services: Peptide Synthesis

Non-neutralizing SARS-CoV-2 N-terminal domain antibodies protect mice against severe disease using Fc-mediated effector functions

Authors: Camille N Pierre, Lily E Adams, Kara Anasti, Derrick Goodman, Sherry Stanfield-Oakley, John M Powers, Dapeng Li, Wes Rountree, Yunfei Wang, Robert J Edwards, S Munir Alam, Guido Ferrari, Georgia D Tomaras, Barton F Haynes, Ralph S Baric, Kevin O Saunders

Journal: biorxiv

PubMed ID: 37546738

Doi: 10.1101/2023.07.25.550460

Products & Services: Molecular Biology Reagents