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A conserved protein tyrosine phosphatase, PTPN-22, functions in diverse developmental processes in

Authors: Shaonil Binti, Adison G Linder, Philip T Edeen, David S Fay

Journal: biorxiv

PubMed ID: 38559252

Doi: 10.1101/2024.03.12.584557

Upregulation of CIRP by its agonist prevents the development of heart failure in myocardial infarction rats

Authors: Jingjing Zhang, Tao Liu, Yanzhao Wei, Jianye Peng, Gaofeng Zeng, Peng Zhong

Journal: BMC Cardiovasc Disord

PubMed ID: 38539067

Doi: 10.1186/s12872-024-03852-9

Products & Services: Gene Synthesis

Aging-induced tRNAGlu-derived fragment impairs glutamate biosynthesis by targeting mitochondrial translation-dependent cristae organization

Authors: Dingfeng Li, Xinyi Gao, Xiaolin Ma, Ming Wang, Chuandong Cheng, Tian Xue, Feng Gao, Yong Shen, Juan Zhang, Qiang Liu

Journal: Cell Metab

PubMed ID: 38458203

Doi: 10.1016/j.cmet.2024.02.011.

Products & Services: Custom DNA/RNA Oligos

Occlusal force orchestrates alveolar bone homeostasis via Piezo1 in female mice

Authors: Yiling Yang, Qinggang Dai, Xin Gao, Yanfei Zhu, Mi Ri Chung, Anting Jin, Yuanqi Liu, Xijun Wang, Xiangru Huang, Siyuan Sun, Hongyuan Xu, Jingyi Liu, Lingyong Jiang

Journal: J Bone Miner Res

PubMed ID: 38477783

Doi: 10.1093/jbmr/zjae032

Products & Services: Protein Electrophoresis and Western

Unveiling a Shield of Hope: A Novel Multiepitope-Based Immunogen for Cross-Serotype Cellular Defense against Dengue Virus

Authors: Nilanshu Manocha, Daphné Laubreton, Xavier Robert, Jacqueline Marvel, Virginie Gueguen-Chaignon, Patrice Gouet, Prashant Kumar, Madhu Khanna

Journal: Vaccines (Basel)

PubMed ID: 38543950

Doi: 10.3390/vaccines12030316

Products & Services: Catalog Peptides

Nintedanib downregulates the profibrotic M2 phenotype in cultured monocyte-derived macrophages obtained from systemic sclerosis patients affected by interstitial lung disease

Authors: Stefano Soldano, Vanessa Smith, Paola Montagna, Emanuele Gotelli, Rosanna Campitiello, Carmen Pizzorni, Sabrina Paolino, Alberto Sulli, Andrea Cere, Maurizio Cutolo

Journal: Arthritis Res Ther

PubMed ID: 38509595

Doi: 10.1186/s13075-024-03308-7

Products & Services: Protein and Antibody Isolation

Zoledronic Acid Accelerates ER Stress-Mediated Inflammation by Increasing PDE4B Expression in Bisphosphonate-Related Osteonecrosis of the Jaw

Authors: Qu Xz, Sun Zq, Liu L, Ong Hs

Journal: Appl Biochem Biotechnol

PubMed ID: 38523176

Doi: 10.1007/s12010-024-04859-w

Products & Services: Gene Synthesis

Supra-biological performance of immobilized enzymes enabled by chaperone-like specific non-covalent interactions

Authors: Héctor Sánchez-Morán, Joel L Kaar, Daniel K Schwartz

Journal: Nat Commun

PubMed ID: 38485940

Doi: 10.1038/s41467-024-46719-5

Products & Services: Molecular Biology Reagents

Structural determination and kinetic analysis of the transketolase from Vibrio vulnificus reveal unexpected cooperative behavior

Authors: Rainier-Numa Georges, Lionel Ballut, Guillaume Octobre, Arnaud Comte, Laurence Hecquet, Franck Charmantray, Bastien Doumèche

Journal: Protein Sci

PubMed ID: 38145310

Doi: 10.1002/pro.4884

Products & Services: Molecular Biology Reagents

Post-therapeutic cure criterion in chronic Chagas disease using Trypanosoma cruzi chimeric proteins

Authors: Tycha Bianca Sabaini Pavan, Leonardo Maia Leony, Wayner Vieira de Souza, Emily Ferreira Santos, Ramona Tavares Daltro, Natalia Erdens Maron Freitas, Larissa Carvalho Medrado Vasconcelos, Fernanda Lopes Habib, Angelo Antonio Oliveira Silva, Paola Alejandra Fiorani Celedon, Daniel Dias Sampaio, Nilson Ivo Tonin Zanchin, Silvia Andrea Longhi, Fred Luciano Neves Santos

Journal: Folia Parasitol (Praha)

PubMed ID: 38526232

Doi: 10.14411/fp.2024.004

Products & Services: Gene Synthesis