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Design of amyloidogenic peptide traps

Authors: Danny D Sahtoe, Ewa A Andrzejewska, Hannah L Han, Enrico Rennella, Matthias M Schneider, Georg Meisl, Maggie Ahlrichs, Justin Decarreau, Hannah Nguyen, Alex Kang, Paul Levine, Mila Lamb, Xinting Li, Asim K Bera, Lewis E Kay, Tuomas P J Knowles, David Baker

Journal: Nature Chemical Biology

PubMed ID: 38503834

Doi: 10.1038/s41589-024-01578-5

Products & Services: Gene Synthesis

Structure of the human KMN complex and implications for regulation of its assembly

Authors: Soumitra Polley, Tobias Raisch, Sabrina Ghetti, Marie Körner, Melina Terbeck, Frauke Gräter, Stefan Raunser, Camilo Aponte-Santamaría, Ingrid R Vetter, Andrea Musacchio

Journal: NATURE STRUCTURAL & MOLECULAR BIOLOGY

PubMed ID: 38459128

Doi: 10.1038/s41594-024-01230-9

Products & Services: Peptide Synthesis

Preparation and characterization of a novel humanized collagen III with repeated fragments of Gly300-Asp329

Authors: Lingying Yan, Yao Zhang, Yuxiang Zhang, Qiexin Chen, Luyao Zhang, Xiao Han, Yumo Yang, Chun Zhang, Yongdong Liu, Rong Yu

Journal: Protein Expr Purif

PubMed ID: 38508543

Doi: 10.1016/j.pep.2024.106473

Products & Services: Protein Electrophoresis and Western

Establishment, optimization and validation of a fluorescence polarization-based high-throughput screening assay targeting cathepsin L inhibitors

Authors: Wenwen Zhou, Baoqing You, Xiaomeng Zhao, Shuyi Si, Yan Li, Jing Zhang

Journal: SLAS Discov

PubMed ID: 38518956

Doi: 10.1016/j.slasd.2024.100153

Products & Services: Serology SARS-Cov-2 detection kits

Histoplasma antigens as novel players for the development of new enzyme immunoassays for the serodiagnosis of histoplasmosis: A comparative study of their analytical performance

Authors: Carolina Rodríguez Laboccetta, Víctor J Briceño Fernández, Agustín Videla Garrido, Gladys B Posse, María L Cuestas, Alejandro D Nusblat

Journal: Med Mycol

PubMed ID: 38479779

Doi: 10.1093/mmy/myae023

Products & Services: Codon Optimization

The riboflavin (vitamin B2) transporter protein (SmaRT) of the human intravascular parasitic trematode Schistosoma mansoni

Authors: Akram A Da'dara, Roshni Gondane, Patrick J Skelly

Journal: Heliyon

PubMed ID: 38601580

Doi: 10.1016/j.heliyon.2024.e28271

Products & Services: Catalog Peptides

Chinese bayberry ( Sieb et Zucc) leaves proanthocyanidins inhibit intestinal glucose transport in human Caco-2 cells

Authors: Mengting Wang, Haiguang Mao, Zhijian Ke, Jianchu Chen, Lili Qi, Jinbo Wang

Journal: Front Pharmacol

PubMed ID: 38529186

Doi: 10.3389/fphar.2024.1284268

Products & Services: Catalog Antibodies

VCF1 is a p97/VCP cofactor promoting recognition of ubiquitylated p97-UFD1-NPL4 substrates

Authors: Ann Schirin Mirsanaye, Saskia Hoffmann, Melanie Weisser, Andreas Mund, Blanca Lopez Mendez, Dimitris Typas, Johannes van den Boom, Bente Benedict, Ivo A Hendriks, Michael Lund Nielsen, Hemmo Meyer, Julien P Duxin, Guillermo Montoya, Niels Mailand

Journal: Nat Commun

PubMed ID: 38503733

Doi: 10.1038/s41467-024-46760-4

Products & Services: Catalog Peptides

The scale of zebrafish pectoral fin buds is determined by intercellular K+ levels and consequent Ca2+-mediated signaling via retinoic acid regulation of Rcan2 and Kcnk5b

Authors: Xiaowen Jiang, Kun Zhao, Yi Sun, Xinyue Song, Chao Yi, Tianlong Xiong, Sen Wang, Yi Yu, Xiduo Chen, Run Liu, Xin Yan, Christopher L Antos

Journal: PLoS Biol

PubMed ID: 38527087

Doi: journal.pbio.3002565

Products & Services: Catalog Gene Editing

An optimized high-throughput SARS-CoV-2 dual reporter trans-complementation system for antiviral screening in vitro and in vivo

Authors: Yingjian Li, Xue Tan, Jikai Deng, Xuemei Liu, Qianyun Liu, Zhen Zhang, Xiaoya Huang, Chao Shen, Ke Xu, Li Zhou, Yu Chen

Journal: Virol Sin

PubMed ID: 38548102

Doi: 10.1016/j.virs.2024.03.009

Products & Services: Gene Synthesis