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Arabidopsis response to the apocarotenoid zaxinone involves interference with strigolactone signaling via binding to DWARF14

Authors: Juan C Moreno, Umar F Shahul Hameed, Aparna Balakrishna, Abdugaffor Ablazov, Kit Xi Liew, Muhammad Jamil, Jianing Mi, Kawthar Alashoor, Alexandre de Saint Germain, Stefan T Arold, Salim Al-Babili

Journal: Nature Communications

PubMed ID: 41038837

Doi: 10.1038/s41467-025-63845-w

Metabolic Hijacking by Engineered Probiotics Reprograms Tumor Metabolism and Immune Microenvironment for Self-Reinforcing Photodynamic Immunotherapy

Authors: Shurong Qin, Qi Wang, Zhuangwei Zhang, Junhui Gu, Guanzhong He, Fei Zeng, Ruiyue Chen, Bangshun He, Yuzhen Wang, Meng Wang, Yujun Song

Journal: Journal of the American Chemical Society

PubMed ID: 41059938

Doi: 10.1021/jacs.5c10242

Products & Services: Recombinant Proteins

ZBP1 pathway promotes tumor immunogenicity in thecombinationofanti-HER2therapyandepigenetic therapy

Authors: Qishan Wang, Zhihao Wu, Yuanqin Yang, Chao Yang, Haoran Deng, Xingyue Zhou, Shuting Xu, Lingling Wu, Xiaochuan Hong, Xueni Yu, Lu Lu, Liufu Deng

Journal: Cell Reports

Doi: 10.1016/j.celrep.2025.116314

Products & Services: Protein Electrophoresis and Western

Functional RNA splitting drove the evolutionary emergence of type V CRISPR-Cas systems from transposons

Authors: Shuai Jin, Zixu Zhu, Yunjia Li, Shouyue Zhang, Yijing Liu, Danyuan Li, Yuanqing Li, Yingfeng Luo, Zhiheng Cheng, Kevin Tianmeng Zhao, Qiang Gao, Guanglei Yang, Hongchao Li, Ronghong Liang, Rui Zhang, Jin-Long Qiu, Yong E Zhang, Jun-Jie Gogo Liu, Caixia Gao

Journal: Cell

PubMed ID: 41027434

Doi: doi.org/10.1016/j.cell.2025.09.004

Products & Services: Codon Optimization PCR Cloning and Subcloning

Neutrophil elastase-activatable ratiometric photoacoustic nanoprobes for imaging atherosclerotic plaque vulnerability

Authors: Hui Cao, Xin Meng, Yuan Ma, Zhe Li, Xinyu Xu, Jiaqi Fu, Qingpeng Zhang, Hanlin Wei, Peng Liang, Dingyou Lu, Jinyu Li, Baoli Yin, Shuangyan Huan, Xiao-Bing Zhang, Guosheng Song

Journal: Nature Communications

PubMed ID: 41173886

Doi: 10.1038/s41467-025-64633-2

Products & Services: Catalog Peptides

TOPO-seq reveals DNA topology-induced off-target activity by Cas9 and base editors

Authors: Min Duan, Pan Gao, Yi-Zhou Zhang, Yu-Long Hu, Lei Zhou, Zhong-Chen Xu, Hou-Yuan Qiu, Xiao-Han Tong, Rui-Jin Ji, Xin-Lin Lei, Hao Yin, Cun-Lan Guo, Ying Zhang

Journal: Nature Chemical Biology

PubMed ID: 40175512

Doi: 10.1038/s41589-025-01867-7

Products & Services: Synthetic Guide RNA

A motif preferred adenine base editor with minimal bystander and off-targets editing

Authors: Mengyu Shang, Yinuo Li, Qiuyu Cao, Jingxuan Ren, Yuqiang Zeng, Jinxin Wang, Rachel V. L. Gonzalez & Xiaohui Zhang

Journal: Nature Communications

PubMed ID: 41093849

Doi: 10.1038/s41467-025-64203-6

Structural insights into the mechanism of activation and inhibition of the prostaglandin D2 receptor 1

Authors: Behnaz Davoudinasab, Aleksey Raskovalov, Woojin Lee, Donggyun Kim, Heesoo Kim, Jordy Homing Lam, Gye Won Han, Vsevolod Katritch, Vadim Cherezov

Journal: Nature Communications

PubMed ID: 41062467

Doi: 10.1038/s41467-025-64002-z

A dirigent protein redirects extracellular terpenoid metabolism for defense against biotic challenges

Authors: Jia-Ling Lin, Wen-Kai Wu, Gui-Bin Nie, Jian-Xu Li, Xin Fang, Yin-Guo Sheng, Meng-Meng Wang, Qi-Yue Zheng, Xiao-Xiang Guo, Jia-Fa Huang, Li-Ying Ma, Ling-Jian Wang, Jia-Xin Liu, Shan-Shan Wang, Baofu Xu, Yiqun Gao, Yan Li, Dong Wang, Cathie Martin, Xiao-Ya Chen & Jin-Quan Huang

Journal: Nature Communications

PubMed ID: 41115945

Doi: 10.1038/s41467-025-64323-z

Products & Services: Protein Electrophoresis and Western

Enteropathogenic bacteria evade ROCK-driven epithelial cell extrusion

Authors: Giovanni Luchetti, Marin V. Miner, Rachael M. Peterson, William P. Scott, Praveen Krishnamoorthy, Eric M. Kofoed, Angel G. Jimenez, Hua Zhang, Man Wah Tan, Rohit Reja, Tommy K. Cheung, Elizabeth Skippington, Yuxin Liang, Christopher M. Rose, Nobuhiko Kayagaki, Kim Newton, Isabella Rauch & Vishva M. Dixit

Journal: Nature

PubMed ID: 41125892

Doi: 10.1038/s41586-025-09645-0