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Sickle cell disease induces chromatin introversion and ferroptosis in CD8+ T cells to suppress anti-tumor immunity

Authors: Zilong Zhao, Benxia Hu, Yalan Deng, Melinda Soeung, Jun Yao, Lanxin Bei, Yaohua Zhang, Pengju Gong, Lisa A Huang, Zhou Jiang, Jian Gao, Shuang Peng, Tina K Nguyen, Menuka Karki, Bora Lim, Cassian Yee, Jared K Burks, Qing Zhang, Li Ma, Jianjun Gao, Nizar M Tannir, Leng Han, Dihua Yu, Linghua Wang, Michael A Curran, Maria A Gubbiotti, Giannicola Genovese, Boyi Gan, Wenbo Li, Pavlos Msaouel, Liuqing Yang, Chunru Lin

Journal: Immunity

PubMed ID: 40359940

Doi: 10.1016/j.immuni.2025.04.020

Products & Services: Protein and Antibody Isolation

LRM3 positively regulates stem lodging resistance by degradating MYB6 transcriptional repressor in soybean

Authors: Yongheng Ye, Zhiyuan Cheng, Xinjing Yang, Suxin Yang, Kuanqiang Tang, Hui Yu, Jinshan Gao, Yaohua Zhang, Jiantian Leng, Wei Zhang, Ye Zhang, Moran Bu, Zhengwei Liang, Zhicheng Dong, Zhonghui Zhang, Xianzhong Feng

Journal: Plant Biotechnology Journal.

PubMed ID: 40333576

Doi: 10.1111/pbi.70124

Products & Services: Protein Electrophoresis and Western

A non-tethering role for the Drosophila Pol θ linker domain in promoting damage resolution

Authors: Justin R Blanch, Nicholas Woodward, Manan Krishnamurthy, Mitch McVey

Journal: Nucleic Acids Research

PubMed ID: 40275613

Doi: 10.1093/nar/gkaf304

Products & Services: Protein Electrophoresis and Western

Engineering aptamer-directed phosphatase recruiting chimeras: a strategy for modulating receptor function and overcoming drug resistance

Authors: Zhilan Zhou, Yichang Liu, Ya Wang, Hang Jiang, Tingting Chen, Yingdi Zhu, Ting Fu, Juan Li

Journal: Nature Communications

PubMed ID: 40280908

Doi: 10.1038/s41467-025-59098-2

Products & Services: Protein Electrophoresis and Western

Examining the Role of Threonine Phosphorylation in Ubiquitin’s Function Using Chemical Protein Synthesis

Authors: Bingji Wang, Chuntong Li, Fangyu Zhao, Luyu Shi, Xu Li, Yijie Liu, Shuzhe Sun, Ligong Yuan, Maoshen Sun, Yingyue Zhang, Jing Shi, Lu-Jun Liang

Journal: JACS Au

Doi: doi/10.1021/jacsau.5c00067

Products & Services: Protein Electrophoresis and Western

Potential role of TRAF2 in pulmonary hypertension in broiler chickens and preparation and specificity analysis of its polyclonal antibody

Authors: Wen Peng, Gen Wan, Sufang Cheng, Guyue Li, Liling Liu, Juan Chen, Pei Liu, Xiaoquan Guo, Xiaona Gao, Gaofeng Cai, Zhanhong Zheng, Ping Liu

Journal: Int J Biol Macromol

PubMed ID: 39798767

Doi: doi.org/10.1016/j.ijbiomac.2025.139741

Products & Services: Protein Electrophoresis and Western

Nucleotide-induced hyper-oligomerization inactivates transcription termination factor ρ

Authors: Bing Wang, Nelly Said, Tarek Hilal, Mark Finazzo, Markus C Wahl, Irina Artsimovitch

Journal: Nature Communications

PubMed ID: 39952913

Doi: 10.1038/s41467-025-56824-8

Products & Services: Protein Electrophoresis and Western

Alternatively spliced NFKB1 transcripts enriched in Andean Aymara modulate inflammation, HIF and hemoglobin

Authors: Jihyun Song, Seonggyun Han, Ricardo Amaru, Lucie Lanikova, Teddy Quispe, Dongwook Kim, Jacob E Crawford, Soo Jin Kim, Younghee Lee, Josef T Prchal

Journal: Nature Communications

PubMed ID: 39971917

Doi: 10.1038/s41467-025-56848-0

Products & Services: Protein Electrophoresis and Western

Structural basis of SIRT7 nucleosome engagement and substrate specificity

Authors: Carlos Moreno-Yruela, Babatunde E Ekundayo, Polina N Foteva, Dongchun Ni, Esther Calvino-Sanles, Henning Stahlberg, Beat Fierz

Journal: Nature Communications

PubMed ID: 39900593

Doi: 10.1038/s41467-025-56529-y

Products & Services: Protein Electrophoresis and Western

Blocking autophagosome closure manifests the roles of mammalian Atg8-family proteins in phagophore formation and expansion during nutrient starvation

Authors: Van Bui , Xinwen Liang , Yansheng Ye , William Giang , Fang Tian , Yoshinori Takahashi , Hong-Gang Wang