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Molecular basis for substrate transport of Mycobacterium tuberculosis ABC importer DppABCD

Authors: Tianyu Hu, Xiaolin Yang, Yuanchen Zhu, Fengjiang Liu, Xiuna Yang, Zhiqi Xiong, Jingxi Liang, Zhenli Lin, Yuting Ran, Luke W Guddat, Zihe Rao, Bing Zhang

Journal: SCIENCE ADVANCES

PubMed ID: 38507491

Doi: 10.1126/sciadv.adk8521

Products & Services: Protein and Antibody Isolation

MIWI N-terminal arginines orchestrate generation of functional pachytene piRNAs and spermiogenesis

Authors: Nicholas Vrettos, Jan Oppelt, Ansgar Zoch, Paraskevi Sgourdou, Haruka Yoshida, Brian Song, Ryan Fink, Dónal O'Carroll, Zissimos Mourelatos 1

Journal: Nucleic Acids Research

PubMed ID: 38520410

Doi: 10.1093/nar/gkae193

Products & Services: Peptide Synthesis

An intein-based biosensor to measure protein stability in vivo

Authors: Ahyun Son, John S Smetana, Scott Horowitz , Christopher W Lennon

Journal: Protein Sci

PubMed ID: 38380775

Doi: 10.1002/pro.4925

Products & Services: Gene Synthesis

Structural basis of U12-type intron engagement by the fully assembled human minor spliceosome

Authors: Rui Bai, Meng Yuan, Pu Zhang, Ting Luo, Yigong Shi, Ruixue Wan

Journal: Science

PubMed ID: 38484052

Doi: 10.1126/science.adn7272

Products & Services: Gene Synthesis

Tight junction protein cingulin variant is associated with cancer susceptibility by overexpressed IQGAP1 and Rac1-dependent epithelial-mesenchymal transition

Authors: Yi-Ting Huang, Ya-Ting Hsu, Pei-Ying Wu, Yu-Min Yeh, Peng-Chan Lin, Keng-Fu Hsu, Meng-Ru Shen

Journal: J Exp Clin Cancer Res

PubMed ID: 38424547

Doi: 10.1186/s13046-024-02987-z

Products & Services: Custom DNA/RNA Oligos

Therapeutic targeting nudix hydrolase 1 creates a MYC-driven metabolic vulnerability

Authors: Minhui Ye, Yingzhe Fang, Lu Chen, Zemin Song, Qing Bao, Fei Wang, Hao Huang, Jin Xu, Ziwen Wang, Ruijing Xiao, Meng Han, Song Gao, Hudan Liu, Baishan Jiang, Guoliang Qing

Journal: Nat Commun

PubMed ID: 38493213

Doi: 10.1038/s41467-024-46572-6

Products & Services: Synthetic Guide RNA

Effective Gene Therapy for Metachromatic Leukodystrophy Achieved with Minimal Lentiviral Genomic Integrations

Authors: Lucas Tricoli, Sunetra Sase, Julia Hacker, Vi Pham, Sidney Smith, Maxwell Chappell, Laura Breda, Stephanie Hurwitz, Naoto Tanaka, Carlo Castruccio Castracani, Amaliris Guerra, Zhongqi Hou, Lars Schlotawa, Karthikeyan Radhakrishnan, Peter Kurre, Rebecca Ahrens-Nicklas, Laura Adang, Adeline Vanderver, Stefano Rivella

Journal: biorxiv

PubMed ID: 38559013

Doi: 10.1101/2024.03.14.584404

Products & Services: Molecular Biology Reagents

Diverse INOSITOL PHOSPHORYLCERAMIDE SYNTHASE mutant alleles of Physcomitrium patens offer new insight into complex sphingolipid metabolism

Authors: Tegan M Haslam, Cornelia Herrfurth, Ivo Feussner

Journal: New Phytol

PubMed ID: 38523559

Doi: 10.1111/nph.19667

Products & Services: Gene Synthesis

A SARS-CoV-2 Nanobody Displayed on the Surface of Human Ferritin with High Neutralization Activity

Authors: Wenrong Zhang, Haining Wang, Tong Wu, Xintao Gao, Yuting Shang, Zhifang Zhang, Xingjian Liu, Yinü Li

Journal: International journal of nanomedicine

PubMed ID: 38476285

Doi: 10.2147/IJN.S450829

Products & Services: Molecular Biology Reagents

A conserved protein tyrosine phosphatase, PTPN-22, functions in diverse developmental processes in

Authors: Shaonil Binti, Adison G Linder, Philip T Edeen, David S Fay

Journal: biorxiv

PubMed ID: 38559252

Doi: 10.1101/2024.03.12.584557