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CircMIB2 therapy can effectively treat pathogenic infection by encoding a novel protein
Authors: Weiwei Zheng, Linchao Wang, Shang Geng, Liyuan Yang, Xing Lv, Shiying Xin, Tianjun Xu
Journal: Cell Death Dis
PubMed ID: 37652905
Doi: 10.1038/s41419-023-06105-3
Products & Services: Custom RNAi Services   
Structure and design of Langya virus glycoprotein antigens
Authors: Zhaoqian Wang, Matthew McCallum, Lianying Yan, William Sharkey, Young-Jun Park, Ha V Dang, Moushimi Amaya, Ashley Person, Christopher C Broder, David Veesler
Journal: biorxiv
PubMed ID: 37645760
Doi: 10.1101/2023.08.20.554025
Products & Services: ORF cDNA Clones/MolecularCloud   
Structural mechanism of synergistic targeting of the nucleosome by PU1 and C/EBPα
Authors: Tengfei Lian, Ruifang Guan, Bing-Rui Zhou, Yawen Bai
Journal: biorxiv
PubMed ID: 37790476
Doi: 10.1101/2023.08.25.554718
Products & Services: Gene Synthesis   
Stromal cell-derived factor-1 downregulation contributes to neuroprotection mediated by CXC chemokine receptor 4 interactions after intracerebral hemorrhage in rats
Authors: Yu Wu, Zhuwei Zhang, Xiaoou Sun, Jing Wang, Haitao Shen, Xue Sun, Zhong Wang
Journal: CNS Neurosci Ther
PubMed ID: 37614198
Doi: 10.1111/cns.14400
Products & Services: Custom Vector Construction   
Origin of the OAS–RNase L innate immune pathway before the rise of jawed vertebrates via molecular tinkering
Authors: Lingyu Chu , Zhen Gong , Wenqiang Wang , Guan-Zhu Han
Journal: Proceedings of the National Academy of Sciences of the United States of America
PubMed ID: 37487089
Doi: 10.1073/pnas.2304687120
Products & Services: Codon Optimization   
GPCR activation and GRK2 assembly by a biased intracellular agonist
Authors: Jia Duan , Heng Liu , Fenghui Zhao , Qingning Yuan , Yujie Ji , Xiaoqing Cai , Xinheng He , Xinzhu Li , Junrui Li , Kai Wu , Tianyu Gao , Shengnan Zhu , Shi Lin , Ming-Wei Wang , Xi Cheng , Wanchao Yin , Yi Jiang , Dehua Yang , H Eric Xu
Journal: Nature .
PubMed ID: 37532940
Doi: 10.1038/s41586-023-06395-9
Products & Services: Proteins, Expression, Isolation and Analysis   
Structural basis of histone H2A lysine 119 deubiquitination by Polycomb repressive deubiquitinase BAP1/ASXL1
Authors: Jonathan F Thomas, Marco Igor Valencia-Sánchez, Simone Tamburri, Susan L Gloor, Samantha Rustichelli, Victoria Godínez-López, Pablo De Ioannes, Rachel Lee, Stephen Abini-Agbomson, Kristjan Gretarsson, Jonathan M Burg, Allison R Hickman, Lu Sun, Saarang Gopinath, Hailey F Taylor, Zu-Wen Sun, Ryan J Ezell, Anup Vaidya, Matthew J Meiners, Marcus A Cheek, William J Rice, Vladimir Svetlov, Evgeny Nudler, Chao Lu, Michael-Christopher Keogh, Diego Pasini, Karim-Jean Armache
Journal: Sci Adv
PubMed ID: 37556531
Doi: 10.1126/sciadv.adg9832
Products & Services: Proteins, Expression, Isolation and Analysis   
Time-resolved cryo-EM using a combination of droplet microfluidics with on-demand jetting
Authors: Stefania Torino, Mugdha Dhurandhar, Annelore Stroobants, Raf Claessens, Rouslan G Efremov
Journal: Nat Methods
PubMed ID: 37592181
Doi: 10.1038/s41592-023-01967-z
Products & Services: Proteins, Expression, Isolation and Analysis   
Preclinical evaluation of manufacturable SARS-CoV-2 spike virus-like particles produced in Chinese Hamster Ovary cells
Authors: Sergio P Alpuche-Lazcano, Matthew Stuible, Bassel Akache, Anh Tran, John Kelly, Sabahudin Hrapovic, Anna Robotham, Arsalan Haqqani, Alexandra Star, Tyler M Renner, Julie Blouin, Jean-Sébastien Maltais, Brian Cass, Kai Cui, Jae-Young Cho, Xinyu Wang, Daria Zoubchenok, Renu Dudani, Diana Duque, Michael J McCluskie, Yves Durocher
Journal: Commun Med (Lond)
PubMed ID: 37612423
Doi: 10.1038/s43856-023-00340-7
Products & Services: Proteins, Expression, Isolation and Analysis   
Enhancement of Neutralization Responses through Sequential Immunization of Stable Env Trimers Based on Consensus Sequences from Select Time Points by Mimicking Natural Infection
Authors: Mingming Wan, Xiao Yang, Jie Sun, Elena E Giorgi, Xue Ding, Yan Zhou, Yong Zhang, Weiheng Su, Chunlai Jiang, Yaming Shan, Feng Gao
Journal: Int J Mol Sci
PubMed ID: 37628824
Doi: 10.3390/ijms241612642
Products & Services: Gene Synthesis   

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