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Alternative low-populated conformations prompt phase transitions in polyalanine repeat expansions

Authors: Rosa Antón, Miguel Á Treviño, David Pantoja-Uceda, Sara Félix, María Babu, Eurico J Cabrita, Markus Zweckstetter, Philip Tinnefeld, Andrés M Vera, Javier Oroz

Journal: Nature

PubMed ID: 38431667

Doi: 10.1038/s41467-024-46236-5

Products & Services: Gene Synthesis

Filamentous fungus-produced human monoclonal antibody provides protection against SARS-CoV-2 in hamster and non-human primate models

Authors: Franziska K Kaiser, Mariana Gonzalez Hernandez, Nadine Krüger, Ellinor Englund, Wenjuan Du, Anna Z Mykytyn, Mathijs P Raadsen, Mart M Lamers

Journal: Nature Communications

PubMed ID: 38485931

Doi: 10.1038/s41467-024-46443-0

Products & Services: Codon Optimization

Human IgG Fc-engineering for enhanced plasma half-life, mucosal distribution and killing of cancer cells and bacteria

Authors: Stian Foss , Siri A Sakya, Leire Aguinagalde, Marta Lustig, Jutamas Shaughnessy, Ana Rita Cruz , Lisette Scheepmaker, Line Mathiesen, Fulgencio Ruso-Julve, Aina Karen Anthi, Torleif Tollefsrud Gjølberg

Journal: Nature Communications

PubMed ID: 38453922

Doi: 10.1038/s41467-024-46321-9

Products & Services: Gene Synthesis

An alphacoronavirus polymerase structure reveals conserved replication factor functions

Authors: Thomas K Anderson, Peter J Hoferle, Kennan J Chojnacki, Kenneth W Lee, Joshua J Coon, Robert N Kirchdoerfer

Journal: Nucleic Acids Research

PubMed ID: 38442273

Doi: 10.1093/nar/gkae153

Products & Services: Codon Optimization

Determinants of CRISPR Cas12a nuclease activation by DNA and RNA targets

Authors: Eric A Nalefski, Remy M Kooistra, Ishira Parikh, Samantha Hedley, Karunya Rajaraman, Damian Madan

Journal: Nucleic Acids Research

PubMed ID: 38477377

Doi: 10.1093/nar/gkae152

Products & Services: Gene Synthesis

Application of Recombinant Lactic Acid Bacteria (LAB) Live Vector Oral Vaccine in the Prevention of F4+ Enterotoxigenic

Authors: Jiangxu Yu, Jiyang Fu, Hongshuo Liu, Chao Kang, Zesong Wang, Yancheng Jin, Shuxuan Wu, Tianzhi Li, Ruicheng Yang, Meilin Jin, Huanchun Chen, Xiangru Wang

Journal: Vaccines (Basel)

PubMed ID: 38543938

Doi: 10.3390/vaccines12030304

Products & Services: Gene Synthesis

EGFR amplification and EGFRvIII predict and participate in TAT-Cx43266-283 antitumor response in preclinical glioblastoma models

Authors: Andrea Álvarez-Vázquez, Laura San-Segundo, Pilar Cerveró-García, Raquel Flores-Hernández, Claudia Ollauri-Ibáñez, Berta Segura-Collar, C G Hubert, Gillian Morrison, Steven M Pollard, Justin D Lathia, Pilar Sánchez-Gómez, Arantxa Tabernero

Journal: Neuro Oncol

PubMed ID: 38507464

Doi: 10.1093/neuonc/noae060

Products & Services: Codon Optimization

Dual mechanisms contribute to enhanced voltage dependence of an electric fish potassium channel

Authors: Jelena Todorovic, Immani Swapna, Antonio Suma, Vincenzo Carnevale, Harold Zakon

Journal: Biophys J

PubMed ID: 38429925

Doi: 10.1016/j.bpj.2024.02.028

Products & Services: Catalog Peptides

Antigenicity, epitope mapping, and intracellular distribution of the NSP7α protein of porcine reproductive and respiratory syndrome virus

Authors: Tao Wang, Da-Song Xia, Xiao-Xiao Tian, Yong-Bo Yang, Tong-Qing An

Journal: Int J Biol Macromol

PubMed ID: 38493809

Doi: 10.1016/j.ijbiomac.2024.130944

Products & Services: Protein and Antibody Isolation

Engineering a Lactobacillus Lysine Riboswitch to Dynamically Control Metabolic Pathways for Lysine Production in

Authors: Qingwei Jiang, Feng Geng, Juan Shen, Ping Zhu, Zhaoxin Lu, Libang Zhou, Fengxia Lu

Journal: Microorganisms

PubMed ID: 38543657

Doi: 10.3390/microorganisms12030606

Products & Services: Custom DNA/RNA Oligos