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Selection, activity, and nuclease stabilization of cross-neutralizing DNA aptamers targeting HSV-1 and HSV-2

Authors: Michael D Schump, David I Bernstein, Fernando J Bravo, Charles P Neff

Journal: Virology

PubMed ID: 37925791

Doi: 10.1016/j.virol.2023.109916

Products & Services: Molecular Biology Reagents

Rapamycin nanoparticles increase the therapeutic window of engineered interleukin-2 and drive expansion of antigen-specific regulatory T cells for protection against autoimmune disease

Authors: Takashi Kei Kishimoto, Max Fournier, Alicia Michaud, Gina Rizzo, Christopher Roy, Teresa Capela, Natasha Nukolova, Ning Li, Liam Doyle, Fen-Ni Fu, Derek VanDyke, Peter G Traber, Jamie B Spangler, Sheldon S Leung, Petr O Ilyinskii

Journal: J Autoimmun

PubMed ID: 37844543

Doi: 10.1016/j.jaut.2023.103125

Products & Services: Protein and Antibody Isolation

Analytical Ultracentrifugation Detects Quaternary Rearrangements and Antibody-Induced Conformational Selection of the SARS-CoV-2 Spike Trimer

Authors: Giuditta Guerrini, Dora Mehn, Francesco Fumagalli, Sabrina Gioria, Mattia Pedotti, Luca Simonelli, Filippo Bianchini, Davide F Robbiani, Luca Varani, Luigi Calzolai

Journal: Int J Mol Sci

PubMed ID: 37834322

Doi: 10.3390/ijms241914875

Products & Services: Custom DNA/RNA Oligos

Binding mechanism and biological effects of flavone DYRK1A inhibitors for the design of new antidiabetics

Authors: Katarzyna Pustelny, Przemyslaw Grygier, Agata Barzowska, Barbara Pucelik, Alex Matsuda, Krzysztof Mrowiec, Emilia Slugocka, Grzegorz M Popowicz, Grzegorz Dubin, Anna Czarna

Journal: Sci Rep

PubMed ID: 37872245

Doi: 10.1038/s41598-023-44810-3

Products & Services: Plasmid DNA Preparation

Industry updates from the field of stem cell research and regenerative medicine in August 2023

Authors: Dusko Ilic, Mirjana Liovic

Journal: Regen Med

PubMed ID: 37786963

Doi: 10.2217/rme-2023-0181

Products & Services: Protein and Antibody Isolation

Author Correction: A ferritin-based COVID-19 nanoparticle vaccine that elicits robust, durable, broad-spectrum neutralizing antisera in non-human primates

Authors: Payton A-B Weidenbacher, Mrinmoy Sanyal, Natalia Friedland, Shaogeng Tang, Prabhu S Arunachalam, Mengyun Hu, Ozan S Kumru, Mary Kate Morris, Jane Fontenot, Lisa Shirreff, Jonathan Do, Ya-Chen Cheng, Gayathri Vasudevan, Mark B Feinberg, Francois J Villinger, Carl Hanson, Sangeeta B Joshi, David B Volkin, Bali Pulendran, Peter S Kim

Journal: Nat Commun

PubMed ID: 37798288

Doi: 10.1038/s41467-023-42061-4

Products & Services: Peptide Synthesis

LRRK2 G2019S promotes astrocytic inflammation induced by oligomeric α-synuclein through NF-κB pathway

Authors: Kai-Jie He, Jin-Bao Zhang, Jun-Yi Liu, Feng-Lun Zhao, Xiao-Yu Yao, Yu-Ting Tang, Jin-Ru Zhang, Xiao-Yu Cheng, Li-Fang Hu, Fen Wang, Chun-Feng Liu

Journal: iScience

PubMed ID: 37876795

Doi: 10.1016/j.isci.2023.108130

Products & Services: Molecular Biology Reagents

β-Arrestin-dependent and -independent endosomal G protein activation by the vasopressin type 2 receptor

Authors: Carole Daly, Akim Abdul Guseinov, Hyunggu Hahn, Adam Wright, Irina G Tikhonova, Alex Rojas Bie Thomsen, Bianca Plouffe

Journal: Elife

PubMed ID: 37855711

Doi: 10.7554/eLife.87754

Products & Services: PCR Cloning and Subcloning

Development and characterization of a prototypic pan-amyloid clearing agent - a novel murine peptide-immunoglobulin fusion

Authors: James S Foster, Manasi Balachandran, Trevor J Hancock, Emily B Martin, Sallie Macy, Craig Wooliver, Tina Richey, Alan Stuckey, Angela D Williams, Joseph W Jackson, Stephen J Kennel, Jonathan S Wall

Journal: Front Immunol

PubMed ID: 37854603

Doi: 10.3389/fimmu.2023.1275372

Products & Services: Molecular Biology Reagents

Whole-genome sequence and mass spectrometry study of the snow blight fungus Phacidium infestans (Karsten) DSM 5139 growing at freezing temperatures

Authors: C Zerouki, K Chakraborty, S Kuittinen, A Pappinen, O Turunen

Journal: Mol Genet Genomics

PubMed ID: 37815644

Doi: 10.1007/s00438-023-02073-7

Products & Services: Combinatorial Mutant library