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Mouse totipotent blastomere-like cells model embryogenesis from zygotic genome activation to post implantation

Authors: Bing Peng , Qingyi Wang , Feixiang Zhang , Hui Shen , Peng Du

Journal: Cell Stem Cell

PubMed ID: 39826539

Doi: doi.org/10.1016/j.stem.2024.12.006

Products & Services: Proteins, Expression, Isolation and Analysis

Increasing brain half-life of antibodies by additional binding to myelin oligodendrocyte glycoprotein, a CNS specific protein

Authors: Marie-Lynn Cuypers; Tom Jaspers; Jarne Clerckx; Simon Leekens; Christopher Cawthorne; Guy Bormans; Frederik Cleeren; Nick Geukens; Bart De Strooper; Maarten Dewilde

Journal: Fluids and barriers of the CNS

PubMed ID: 39885527

Doi: 10.1186/s12987-025-00624-1

Products & Services: Proteins, Expression, Isolation and Analysis

Single-cycle parainfluenza virus type 5 vectors for producing recombinant proteins, including a humanized anti-V5 tag antibody

Authors: Richard E Randall , Dan Young , Maria Pisliakova , Jelena Andrejeva , Lynsey West , Luis Rossler , Volker Morath , David Hughes , Steve Goodbourn

Journal: JOURNAL OF GENERAL VIROLOGY

PubMed ID: 39786361

Doi: 10.1099/jgv.0.002061

Products & Services: Gene Synthesis PCR Cloning and Subcloning

Biochemical characterization and discovery of inhibitors for PfSir2A: new tricks for an old enzyme

Authors: Dickson Donu, Emily Boyle, Alyson Curry, Yana Cen

Journal: RSC Chemical biology

PubMed ID: 39897407

Doi: 10.1039/d4cb00206g

Products & Services: Peptide Synthesis

OGG1 and MUTYH repair activities promote telomeric 8-oxoguanine induced senescence in human fibroblasts

Authors: Mariarosaria De Rosa, Ryan P Barnes, Ariana C Detwiler, Prasanth R Nyalapatla, Peter Wipf, Patricia L Opresko

Journal: Nature Communications

PubMed ID: 39837827

Doi: 10.1038/s41467-024-55638-4

Products & Services: CRISPR Plasmids

Systematic functional characterization of non-coding regulatory SNPs associated with central obesity

Authors: Shan-Shan Dong, Yuan-Yuan Duan, Ren-Jie Zhu, Ying-Ying Jia, Jia-Xin Chen, Xiao-Ting Huang, Shi-Hao Tang, Ke Yu, Wei Shi, Xiao-Feng Chen, Feng Jiang, Ruo-Han Hao, Yunlong Liu, Zhongbo Liu, Yan Guo, and Tie-Lin Yang

Journal: The American Journal of Human Genetics

Doi: doi.org/10.1016/j.ajhg.2024.11.005

Products & Services: Custom DNA/RNA Oligos Oligo pool

Mismatch prime editing gRNA increased efficiency and reduced indels

Authors: Jidong Fei , Dongdong Zhao , Caiyi Pang , Ju Li , Siwei Li , Wentao Qiao , Juan Tan , Changhao Bi , Xueli Zhang

Journal: Nat Commun

PubMed ID: 39747083

Doi: 10.1038/s41467-024-55578-z

Products & Services: Synthetic sgRNA and crRNA Service

Salivary elicitor disulffde isomerase from Nilaparvata lugens targets host rice UDP-glucose epimerase 2 to induce plant defenses

Authors: Jianmei Fu , Zhichang Zhao , Jichao Fang , Rui Ji

Journal: Plant Stress

Doi: doi.org/10.1016/j.stress.2025.100744

Products & Services: Polyclonal Antibody Services

Energy-guided accumulated mutation strategy achieves a highly efficient polyethylene terephthalate-degrading enzyme

Authors: Zhi Wang, Jiaxing Zhang, Shengping You, Rongxin Su, Wei Qi

Journal: Biochemical Engineering Journal

Doi: 10.1016/j.bej.2025.109708

Products & Services: Proteins, Expression, Isolation and Analysis

Discovering CRISPR-Cas system with self-processing pre-crRNA capability by foundation models

Authors: Wenhui Li, Xianyue Jiang, Wuke Wang, Liya Hou, Runze Cai, Yongqian Li, Qiuxi Gu, Qinchang Chen, Peixiang Ma, Jin Tang, Menghao Guo, Guohui Chuai, Xingxu Huang, Jun Zhang, Qi Liu

Journal: Nature Communications

PubMed ID: 39789054

Products & Services: Synthetic sgRNA and crRNA Service