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Diverse Class 2 CRISPR Effectors as Active Nucleases with Expanded Targeting Capabilities

Authors: Meng Wang, Lila Rieber, Jessica van Baaren, Meaghan Morgan, Stephanie Merrett, Ian McDowell, Tyson Bowen

Journal: CRISPR J

PubMed ID: 38635326

Doi: 10.1089/crispr.2023.0058

Products & Services: Codon Optimization

Identification of Enhanced Vaccine Mimotopes for the p15E Murine Cancer Antigen

Authors: Shiqi Zhou, Yiting Song, Yuan Luo, Breandan Quinn, Yang Jiao, Mark D Long, Scott I Abrams, Jonathan F Lovell

Journal: Cancer Res Commun

PubMed ID: 38506662

Doi: 10.1158/2767-9764.CRC-23-0384

Products & Services: Catalog Peptides

Deciphering the unique autoregulatory mechanisms and substrate specificity of the understudied DCLK3 kinase linked to neurodegenerative diseases

Authors: Jason D. Lu; Peng Zhao; Anup Prasad; Neha Gupta; Nathan Gravel; Tej Shidhaye; Lance Wells; Samiksha Katiyar; Natarajan Kannan

Journal: The Journal of Biological Chemistry

PubMed ID: 40902973

Doi: 10.1016/j.jbc.2025.110664

Expanding the druggable zinc-finger proteome defines properties of drug-induced degradation

Authors: Miko aj S abicki; Jiho Park; Rados aw P. Nowak; Shourya S. Roy Burman; Jesse Pellman; Charles Zou; Hlib Razumkov; Jeannie Carreiro; Simran Rastogi; Anna Goldstein; Marek M. Nagiec; Katherine A. Donovan; Jianwei Che; Moritz Hunkeler; Qixiang Geng; Chi-Lin Hsu; Megha Lakshminarayan; Chelsea Shu; Rebecca L. Zon; Zuzanna Kozicka; Paul M.C. Park; Jonathan M. Tsai; Hojong Yoon; Lyn H. Jones; Adam S. Sperling; Nathanael S. Gray; Eric S. Fischer; Benjamin L. Ebert

Journal: Molecular Cell

PubMed ID: 40845806

Doi: 10.1016/j.molcel.2025.07.019

Expanding the druggable zinc-finger proteome defines properties of drug-induced degradation

Journal: Molecular Cell

PubMed ID: 40845806

Doi: 10.1016/j.molcel.2025.07.019

Expanding the druggable zinc-finger proteome defines properties of drug-induced degradation

Journal: Molecular Cell

PubMed ID: 40845806

Doi: 10.1016/j.molcel.2025.07.019

Decoding the blueprint of receptor binding by filoviruses through large-scale binding assays and machine learning

Authors: Gorka Lasso; Michael Grodus; Estefania Valencia; Veronica DeJesus; Eliza Liang; Isabel Delwel; Rob H. Bortz; Dmitry Lupyan; Hanna Y. Ehrlich; Adrian A. Castellanos; Andrea Gazzo; Heather L. Wells; Supaporn Wacharapluesadee; Alexandre Tremeau-Bravard; Janine F.R. Seetahal; Tom Hughes; Jimmy Lee; Mei-Ho Lee; Anna R. Sjodin; Marike Geldenhuys; Marinda Mortlock; Isamara Navarrete-Macias; Kirsten Gilardi; Michael R. Willig; Alessandra F.D. Nava; Elisabeth H. Loh; Makda Asrat; Tierra Smiley-Evans; Walter S. Magesa; Sijali Zikankuba; David Wolking; Gerardo Suz n; Rafael Ojeda-Flores; Christine V.F. Carrington; Ariful Islam; Jonathan H. Epstein; Wanda Markotter; Christine K. Johnson; Tracey Goldstein; Barbara A. Han; Jonna A.K. Mazet; Rohit K. Jangra; Kartik Chandran; Simon J. Anthony

Journal: Cell Host & Microbe

PubMed ID: 39818205

Doi: 10.1016/j.chom.2024.12.016

Products & Services: Protein and Antibody Isolation

CRISPR/CasΦ2-mediated gene editing in wheat and rye

Authors: Sanzeng Zhao , Xueying Han , Yachen Zhu , Yuwei Han , Huiyun Liu , Zhen Chen , Huifang Li , Dan Wang , Chaofan Tian , Yuting Yuan , Yajie Guo , Xiaomin Si , Daowen Wang, Xiang Ji

Journal: J Integr Plant Biol

PubMed ID: 38351739

Doi: 10.1111/jipb.13624

Products & Services: Synthetic Guide RNA

Bioactive fiber-reinforced hydrogel to tailor cell microenvironment for structural and functional regeneration of myotendinous junction

Authors: Yuzhi Sun 1, Renwang Sheng 2, Zhicheng Cao 1, Chuanquan Liu 2, Jiaxiang Li 1, Po Zhang 1, Yan Du 2, Qingyun Mo 2, Qingqiang Yao 1 3, Jialin Chen 2 3 4, Wei Zhang 2 3 4

Journal: Sci Adv

PubMed ID: 38657071

Doi: 10.1126/sciadv.adm7164

Products & Services: Recombinant Proteins

The Transpeptidase Sortase A Binds Nucleic Acids and Mediates Mammalian Cell Labeling

Authors: Yingzheng Liu, Zhike Lu, Panfeng Wu, Zhaohui Liang, Zhenxing Yu, Ke Ni, Lijia Ma

Journal: Adv Sci (Weinh)

PubMed ID: 38581131

Doi: 10.1002/advs.202305605

Products & Services: Protein and Antibody Isolation