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Deciphering the unique autoregulatory mechanisms and substrate specificity of the understudied DCLK3 kinase linked to neurodegenerative diseases

Authors: Jason D. Lu; Peng Zhao; Anup Prasad; Neha Gupta; Nathan Gravel; Tej Shidhaye; Lance Wells; Samiksha Katiyar; Natarajan Kannan

Journal: The Journal of Biological Chemistry

PubMed ID: 40902973

Doi: 10.1016/j.jbc.2025.110664

Virtual screening and evaluation of bioactive peptides from Haliotis discus hannai as potential HMGCR inhibitors for hyperlipidemia treatment

Authors: Kun Qiao; Lina Liu; Yihui Chen; Qiongmei Huang; Bei Chen; Jingna Wu; Wenmei Huang; Zhiyu Liu

Journal: Frontiers in nutrition

PubMed ID: 39811675

Doi: 10.3389/fnut.2024.1525768

Products & Services: Peptide Synthesis

Virtual screening and evaluation of bioactive peptides from Haliotis discus hannai as potential HMGCR inhibitors for hyperlipidemia treatment

Authors: Kun Qiao; Lina Liu; Yihui Chen; Qiongmei Huang; Bei Chen; Jingna Wu; Wenmei Huang; Zhiyu Liu

Journal: Frontiers in nutrition

PubMed ID: 39811675

Doi: 10.3389/fnut.2024.1525768

Products & Services: Peptide Synthesis

Genetic mechanisms underlying the structural elaboration and dissemination of viral internal ribosomal entry sites

Authors: Irina S Abaeva, Tatyana V Pestova, Christopher U T Hellen

Journal: biorxiv

PubMed ID: 38883778

Doi: 10.1093/nar/gkag629

Products & Services: Gene Synthesis

Cancer-associated polybromo-1 bromodomain 4 missense variants variably impact bromodomain ligand binding and cell growth suppression

Authors: Karina L. Bursch; Christopher J. Goetz; Guanming Jiao; Raymundo Nu ez; Michael D. Olp; Alisha Dhiman; Mallika Khurana; Michael T. Zimmermann; Raul A. Urrutia; Emily C. Dykhuizen; Brian C. Smith

Journal: The Journal of Biological Chemistry

PubMed ID: 38460939

Doi: 10.1016/j.jbc.2024.107146

Products & Services: Protein and Antibody Isolation

MCT4 and CD147 colocalize with MMP14 in invadopodia and support matrix degradation and invasion by breast cancer cells

Authors: Signe Meng, Ester E Sørensen, Muthulakshmi Ponniah, Jeppe Thorlacius-Ussing, Roxane Crouigneau, Tanja Larsen, Magnus T Borre, Nicholas Willumsen, Mette Flinck, Stine F Pedersen

Journal: J Cell Sci

PubMed ID: 38661040

Doi: 10.1242/jcs.261608

Products & Services: Protein and Antibody Isolation

Blocking group 2 innate lymphoid cell activation and macrophage M2 polarization: potential therapeutic mechanisms in ovalbumin-induced allergic asthma by calycosin

Authors: Chunyan Tian, Qi Liu, Xiaoyu Zhang, Zhuying Li

Journal: BMC Pharmacol Toxicol

PubMed ID: 38650035

Doi: 10.1186/s40360-024-00751-9

Products & Services: Gene Synthesis

The grapevine miR827a regulates the synthesis of stilbenes by targeting VqMYB14 and gives rise to susceptibility in plant immunity

Authors: Yangyang Luo, Linxia Wang, Jie Zhu, Jingwen Tian, Lin You, Qin Luo, Jia Li, Qian Yao, Dong Duan

Journal: Theor Appl Genet

PubMed ID: 38582777

Doi: 10.1007/s00122-024-04599-9

Products & Services: Custom Vector Construction

Tumor vascular disrupting agent 5,6-dimethylxanthenone-4-acetic acid (DMXAA): Suppresses macrophage capping protein beyond STING activation

Authors: Zhiyong Xiao, Xia Cui, Feng Liu, Ying Wang, Xiao Liu, Wenxia Zhou, Yongxiang Zhang

Journal: Biochim Biophys Acta Mol Basis Dis

PubMed ID: 38565383

Doi: 10.1016/j.bbadis.2024.167149

Products & Services: Protein and Antibody Isolation

Graphene oxide films as a novel tool for the modulation of myeloid-derived suppressor cell activity in the context of multiple sclerosis

Authors: Celia Camacho-Toledano, Isabel Machín-Díaz, Rafael Lebrón-Galán, Ankor González-Mayorga, Francisco J Palomares, María C Serrano, Diego Clemente

Journal: Nanoscale

PubMed ID: 38498071

Doi: 10.1039/d3nr05351b

Products & Services: Peptide Synthesis