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Driving forces behind phase separation of the carboxy-terminal domain of RNA polymerase II

Authors: David Flores-Solis, Irina P Lushpinskaia, Anton A Polyansky, Arya Changiarath, Marc Boehning, Milana Mirkovic, James Walshe, Lisa M Pietrek, Patrick Cramer, Lukas S Stelzl, Bojan Zagrovic, Markus Zweckstetter

Journal: Nat Commun

PubMed ID: 37749095

Doi: 10.1038/s41467-023-41633-8

Products & Services: Proteins, Expression, Isolation and Analysis

One-step production of fully biotinylated and glycosylated human Fc gamma receptors

Authors: Minhyo Kang, Zening Wang, Xin Ge

Journal: Biotechnol Prog

PubMed ID: 37734055

Doi: 10.1002/btpr.3392

Products & Services: Proteins, Expression, Isolation and Analysis

Oligomeric State of β-Coronavirus Non-Structural Protein 10 Stimulators Studied by Small Angle X-ray Scattering

Authors: Wolfgang Knecht, S Zoë Fisher, Jiaqi Lou, Céleste Sele, Shumeng Ma, Anna Andersson Rasmussen, Nikos Pinotsis, Frank Kozielski

Journal: Int J Mol Sci

PubMed ID: 37686452

Doi: 10.3390/ijms241713649

Products & Services: Nucleic Acid Purification & Analysis

Exploiting the aggregation propensity of beta-lactamases to design inhibitors that induce enzyme misfolding

Authors: Ladan Khodaparast, Laleh Khodaparast, Guiqin Wu, Emiel Michiels, Rodrigo Gallardo, Bert Houben, Teresa Garcia, Matthias De Vleeschouwer, Meine Ramakers, Hannah Wilkinson, Ramon Duran-Romaña, Johan Van Eldere, Frederic Rousseau, Joost Schymkowitz

Journal: Nat Commun

PubMed ID: 37689716

Doi: 10.1038/s41467-023-41191-z

Products & Services: Peptide Synthesis

CST2 is activated by RUNX1 and promotes pancreatic cancer progression by activating PI3K/AKT pathway

Authors: Rongwen Ou, Chengjie Lin, Youting Chen

Journal: Arch Biochem Biophys

PubMed ID: 37722526

Doi: 10.1016/j.abb.2023.109760

Products & Services: Custom RNAi Services

Isofagomine inhibits multiple TcdB variants and protects mice from induced mortality

Authors: Ashleigh S Paparella, Isabella Brew, Huynh A Hong, William Ferriera, Simon Cutting, Farah Lamiable-Oulaidi, Michael Popadynec, Peter C Tyler, Vern L Schramm

Journal: biorxiv

PubMed ID: 37781587

Doi: 10.1101/2023.09.19.558375

Products & Services: Combinatorial DNA Libraries

A temperature dependent pilin promoter for production of thermostable enzymes in Thermus thermophilus

Authors: Lennart Kirchner, Volker Müller, Beate Averhoff

Journal: Microb Cell Fact

PubMed ID: 37726752

Doi: 10.1186/s12934-023-02192-1

Products & Services: Codon Optimization

Prime editor-mediated functional reshaping of ACE2 prevents the entry of multiple human coronaviruses, including SARS-CoV-2 variants

Authors: Wenwen Zhao， Jifang Li, Xiao Wang， Wei Xu， Bao-Qing Gao， Jiangchao Xiang， Yaofeng Hou, Wei Liu, Jing Wu, Qilian Qi, Jia Wei, Xiaoyu Yang, Lu Lu,Li Yang, Jia Chen, Bei Yang

Journal: MedComm.

Doi: 10.1002/mco2.356

Products & Services: Gene Synthesis Proteins, Expression, Isolation and Analysis

Unambiguous discrimination of all 20 proteinogenic amino acids and their modifications by nanopore

Authors: Kefan Wang, Shanyu Zhang, Xiao Zhou, Xian Yang, Xinyue Li, Yuqin Wang, Pingping Fan, Yunqi Xiao, Wen Sun, Panke Zhang, Wenfei Li, Shuo Huang

Journal: Nat Methods

PubMed ID: 37749214

Doi: 10.1038/s41592-023-02021-8

Products & Services: Proteins, Expression, Isolation and Analysis

A Humanized Yeast System for Evaluating the Protein Prenylation of a Wide Range of Human and Viral CaaX Sequences

Authors: Emily R Hildebrandt, Anushka Sarkar, Rajani Ravishankar, June H Kim, Walter K Schmidt

Journal: biorxiv