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至今，GenScript的服务及产品已被Cell, Nature, Science, PNAS等1300多家生物医药类杂志引用近万次，处于行业领先水平。NIH、哈佛、耶鲁、斯坦福、普林斯顿、杜克大学等约400家全球著名机构使用GenScript的基因合成、多肽服务、抗体服务和蛋白服务等成功地发表科研成果，再次证明GenScript 有能力帮助业内科学家Make research easy.

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Binding mechanism and biological effects of flavone DYRK1A inhibitors for the design of new antidiabetics

Authors: Katarzyna Pustelny, Przemyslaw Grygier, Agata Barzowska, Barbara Pucelik, Alex Matsuda, Krzysztof Mrowiec, Emilia Slugocka, Grzegorz M Popowicz, Grzegorz Dubin, Anna Czarna

Journal: Sci Rep

PubMed ID: 37872245

Doi: 10.1038/s41598-023-44810-3

Products & Services: Plasmid DNA Preparation

β-Arrestin-dependent and -independent endosomal G protein activation by the vasopressin type 2 receptor

Authors: Carole Daly, Akim Abdul Guseinov, Hyunggu Hahn, Adam Wright, Irina G Tikhonova, Alex Rojas Bie Thomsen, Bianca Plouffe

Journal: Elife

PubMed ID: 37855711

Doi: 10.7554/eLife.87754

Products & Services: PCR Cloning and Subcloning

Whole-genome sequence and mass spectrometry study of the snow blight fungus Phacidium infestans (Karsten) DSM 5139 growing at freezing temperatures

Authors: C Zerouki, K Chakraborty, S Kuittinen, A Pappinen, O Turunen

Journal: Mol Genet Genomics

PubMed ID: 37815644

Doi: 10.1007/s00438-023-02073-7

Products & Services: Combinatorial DNA Libraries

Opsin 5 mediates violet light-induced early growth response-1 expression in the mouse retina

Authors: Heonuk Jeong, Deokho Lee, Xiaoyan Jiang, Kazuno Negishi, Kazuo Tsubota, Toshihide Kurihara

Journal: Sci Rep

PubMed ID: 37857760

Doi: 10.1038/s41598-023-44983-x

Products & Services: Gene Synthesis

Rapamycin nanoparticles increase the therapeutic window of engineered interleukin-2 and drive expansion of antigen-specific regulatory T cells for protection against autoimmune disease

Authors: Takashi Kei Kishimoto, Max Fournier, Alicia Michaud, Gina Rizzo, Christopher Roy, Teresa Capela, Natasha Nukolova, Ning Li, Liam Doyle, Fen-Ni Fu, Derek VanDyke, Peter G Traber, Jamie B Spangler, Sheldon S Leung, Petr O Ilyinskii

Journal: J Autoimmun

PubMed ID: 37844543

Doi: 10.1016/j.jaut.2023.103125

Products & Services: Proteins, Expression, Isolation and Analysis

Nucleic acid-triggered NADase activation of a short prokaryotic Argonaute

Authors: Xiaopan Gao , Kun Shang , Kaixiang Zhu , Linyue Wang , Zhixia Mu , Xingke Fu , Xia Yu , Bo Qin , Hongtao Zhu , Wei Ding , Sheng Cui

Journal: Nature .

PubMed ID: 37783228

Doi: 10.1038/s41586-023-06665-6

Products & Services: DNA Sequencing

Plant-Based Meat Analogues Weaken Gastrointestinal Digestive Function and Show Less Digestibility Than Real Meat in Mice

Authors: Yunting Xie , Linlin Cai , Zhiji Huang , Kai Shan , Xinglian Xu , Guanghong Zhou , Chunbao Li

Journal: J Agric Food Chem .

PubMed ID: 36070521

Doi: 10.1021/acs.jafc.2c04246

Products & Services: Gene Synthesis

Single Amino Acid Mutation Decouples Photochemistry of the BLUF Domain from the Enzymatic Function of OaPAC and Drives the Enzyme to a Switched-on State

Authors: Jinnette Tolentino Collado, Emoke Bodis, Jonatan Pasitka, Mihaly Szucs, Zsuzsanna Fekete, Nikolett Kis-Bicskei, Elek Telek, Kinga Pozsonyi, Sofia M Kapetanaki, Greg Greetham, Peter J Tonge, Stephen R Meech, Andras Lukacs

Journal: J Mol Biol

PubMed ID: 37827329

Doi: 10.1016/j.jmb.2023.168312

Products & Services: Proteins, Expression, Isolation and Analysis

Rational Design of Taxadiene Hydroxylase by Ancestral Enzyme Construction and the Elucidation of Key Amino Acids

Authors: Zihan Zhang, Longhao Huang, Zhi-Jun Zhang, Jian-He Xu, Hui-Lei Yu

Journal: Biochemistry

PubMed ID: 37902563

Doi: 10.1021/acs.biochem.3c00411

Products & Services: Proteins, Expression, Isolation and Analysis

FHL1 promotes chikungunya and o'nyong-nyong virus infection and pathogenesis with implications for alphavirus vaccine design

Authors: Wern Hann Ng, Xiang Liu, Zheng L Ling, Camilla N O Santos, Lucas S Magalhães, Andrew J Kueh, Marco J Herold, Adam Taylor, Joseph R Freitas, Sandra Koit, Sainan Wang, Andrew R Lloyd, Mauro M Teixeira, Andres Merits, Roque P Almeida, Nicholas J C King, Suresh Mahalingam

Journal: Nat Commun

PubMed ID: 37884534

Doi: 10.1038/s41467-023-42330-2

Products & Services: Proteins, Expression, Isolation and Analysis

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