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Circ_0007422 Knockdown Inhibits Tumor Property and Immune Escape of Colorectal Cancer by Decreasing PDL1 Expression in a miR-1256-Dependent Manner

Authors: Dian Yin, Li Yang, Xiu Feng, Xiaolu Zhai, Mei Hua, Jing Liu, Ying Chen

Journal: Mol Biotechnol

PubMed ID: 38253900

Doi: 10.1007/s12033-023-01040-2

Products & Services: Mutant Libraries

Phylogenetic conservation of Trop-2 across species-rodent and primate genomics model anti-Trop-2 therapy for pre-clinical benchmarks

Authors: Emanuela Guerra, Marco Trerotola, Valeria Relli, Rossano Lattanzio, Khouloud Boujnah, Nicole Travali, Antonino Moschella, Paolo Todaro, Laura Pierdomenico, Roberta Di Pietro, Nicola Tinari, Saverio Alberti

Journal: Front Genet

PubMed ID: 38250577

Doi: 10.3389/fgene.2023.1297367

Products & Services: Gene Synthesis

Construction and characterization of a humanized rat model with its application in evaluating the uptake of different statins

Authors: Yuanjin Zhang, Junze Huang, Shengbo Huang, Jie Liu, Luyao Deng, Chenmeizi Liang, Yuanqing Guo, Bingyi Yao, Xin Wang

Journal: Acta Pharm Sin B

PubMed ID: 38572097

Doi: 10.1016/j.apsb.2023.12.019

Products & Services: Gene Synthesis

Synthesis and mechanistic study of ultrashort peptides that inhibits Alzheimer's Aβ-aggregation-induced neurotoxicity

Authors: Naina Sehra, Rajesh Parmar, Indresh K Maurya, Vinod Kumar, Kulbhushan Tikoo, Rahul Jain

Journal: Bioorg Chem

PubMed ID: 38309001

Doi: 10.1016/j.bioorg.2024.107159

Products & Services: Catalog Peptides

NRF2 mutation enhances the immune escape of hepatocellular carcinoma by reducing STING activation

Authors: Cheng Li, Gang Liang, Ke Yan, Yongheng Wang

Journal: Biochem Biophys Res Commun

PubMed ID: 38271834

Doi: 10.1016/j.bbrc.2024.149536

Products & Services: Mutant Libraries

Quaternization drives spleen-to-lung tropism conversion for mRNA-loaded lipid-like nanoassemblies

Authors: Yixuan Huang , Jiacai Wu , Sanpeng Li , Zhen Liu , Zhenghua Li , Boping Zhou , Bin Li

Journal: Theranostics

PubMed ID: 38169552

Doi: 10.7150/thno.90071

Products & Services: Custom DNA/RNA Oligos

Structure basis for recognition of plant Rpn10 by phytoplasma SAP05 in ubiquitin-independent protein degradation

Authors: Liying Zhang, Yunxiang Du, Qian Qu, Qingyun Zheng

Journal: iScience

PubMed ID: 38322988

Doi: 10.1016/j.isci.2024.108892

Products & Services: Protein and Antibody Isolation

Jianpi Antai formula prevents miscarriage by repressing M1 polarization of decidual macrophages through ubiquitination of NLRP3 mediated by MARCH7

Authors: Ying Zhao, Chenyun Miao, Ruye Wang, Yun Chen, Ning Ren, Jing Ma, Tao Gao, Qin Zhang

Journal: J Ethnopharmacol

PubMed ID: 38246482

Doi: 10.1016/j.jep.2024.117796

Products & Services: Protein Electrophoresis and Western

A pathologically expanded, clonal lineage of IL-21 producing CD4+ T cells drives Inflammatory neuropathy

Authors: Maryamsadat Seyedsadr, Madison Bang, Ethan McCarthy, Shirley Zhang, Ho-Chung Chen, Mahnia Mohebbi, Willy Hugo, Jason K Whitmire, Melissa G Lechner, Maureen A Su

Journal: biorxiv

PubMed ID: 38260637

Doi: 10.1101/2024.01.07.574553

Products & Services: ORF cDNA Clones/MolecularCloud

Molecular mechanisms and evolutionary robustness of a color switch in proteorhodopsins

Authors: Jiafei Mao, Xinsheng Jin, Man Shi, David Heidenreich, Lynda J Brown, Richard C D Brown, Moreno Lelli, Xiao He, Clemens Glaubitz

Journal: Sci Adv

PubMed ID: 38266078

Doi: 10.1126/sciadv.adj0384

Products & Services: Custom Vector Construction