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A stapled lipopeptide platform for preventing and treating highly pathogenic viruses of pandemic potential

Authors: Gregory H Bird , J J Patten , William Zavadoski , Nicole Barucci , Marina Godes , Benjamin M Moyer , Callum D Owen , Paul DaSilva-Jardine , Donna S Neuberg , Richard A Bowen , Robert A Davey , Loren D Walensky

Journal: Nat Commun

PubMed ID: 38177138

Doi: 10.1038/s41467-023-44361-1

Products & Services: Plasmid DNA Preparation

Massively parallel profiling of RNA-targeting CRISPR-Cas13d

Authors: Hung-Che Kuo , Joshua Prupes , Chia-Wei Chou , Ilya J Finkelstein

Journal: Nat Commun

PubMed ID: 37034598

Doi: 10.1101/2023.03.27.534188

Products & Services: Custom Vector Construction

Correlations of receptor desensitization of gain-of-function GABRB3 variants with clinical severity

Authors: Susan X N Lin, Philip K Ahring, Angelo Keramidas, Vivian W Y Liao, Rikke S Møller, Mary Chebib, Nathan L Absalom

Journal: Brain

PubMed ID: 37647766

Doi: 10.1093/brain/awad285

Products & Services: Plasmid DNA Preparation

Recombinant protein expression in proteome-reduced cells under aerobic and oxygen-limited regimes

Authors: Alvaro R Lara, Jose Utrilla, Luz María Martínez, Niels Krausch, Lucas Kaspersetz, David Hidalgo, Nicolas Cruz-Bournazou, Peter Neubauer, Juan-Carlos Sigala, Guillermo Gosset, Jochen Büchs

Journal: Biotechnol Bioeng

PubMed ID: 38178599

Doi: 10.1002/bit.28645

Products & Services: Molecular Biology Reagents

9S1R nullomer peptide induces mitochondrial pathology, metabolic suppression, and enhanced immune cell infiltration, in triple-negative breast cancer mouse model

Authors: Nilufar Ali, Cody Wolf, Swarna Kanchan, Shivakumar R Veerabhadraiah, Laura Bond, Matthew W Turner, Cheryl L Jorcyk, Greg Hampikian

Journal: Biomed Pharmacother

PubMed ID: 38118350

Doi: 10.1016/j.biopha.2023.115997.

Products & Services: Peptide Synthesis

Redox signalling regulates breast cancer metastasis via phenotypic and metabolic reprogramming due to p63 activation by HIF1α

Authors: Zuen Ren, Malindrie Dharmaratne, Huizhi Liang, Outhiriaradjou Benard, Miriam Morales-Gallego, Kimita Suyama, Viney Kumar, Atefeh Taherian Fard, Ameya S Kulkarni, Michael Prystowsky, Jessica C Mar, Larry Norton, Rachel B Hazan

Journal: Br J Cancer

PubMed ID: 38238426

Doi: 10.1038/s41416-023-02522-5

Products & Services: ORF cDNA Clones/MolecularCloud

Molecular Atlas of HER2+ Breast Cancer Cells Treated with Endogenous Ligands: Temporal Insights into Mechanisms of Trastuzumab Resistance

Authors: Kavitha Mukund, Jackelyn A Alva-Ornelas, Adam L Maddox, Divya Murali, Darya Veraksa, Andras Saftics, Jerneja Tomsic, David Frankhouser, Meagan Razo, Tijana Jovanovic-Talisman, Victoria L Seewaldt, Shankar Subramaniam

Journal: Cancers (Basel)

PubMed ID: 38339304

Doi: 10.3390/cancers16030553

Products & Services: Recombinant Proteins

Structural determinants of phosphorylation-dependent nuclear transport of HCMV DNA polymerase processivity factor UL44

Authors: Emily M Cross, Oriano Marin, Daryl Ariawan, David Aragão, Giorgio Cozza, Enzo Di Iorio, Jade K Forwood, Gualtiero Alvisi

Journal: FEBS Lett

PubMed ID: 38158756

Doi: 10.1002/1873-3468.14797

Products & Services: Molecular Biology Reagents

Myosin Va-dependent Transport of NMDA Receptors in Hippocampal Neurons

Authors: Ru Gong, Linwei Qin, Linlin Chen, Ning Wang, Yifei Bao, Wei Lu

Journal: Neurosci Bull

PubMed ID: 38291290

Doi: 10.1007/s12264-023-01174-y

Products & Services: Protein and Antibody Isolation

Revamped mini-αA-crystallin showed improved skin permeation and therapeutic activity against melittin-induced toxicity

Authors: Tenzin Tender, Rakesh Ravishankar Rahangdale, Madhavan Nampoothiri, Ruchira Raychaudhuri, Srinivas Mutalik, Krishna Sharma, Raghu Chandrashekar H

Journal: Toxicon

PubMed ID: 38211805

Doi: 10.1016/j.toxicon.2024.107611

Products & Services: Gene Synthesis