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Double-stranded DNA deaminase DddAE1347A can increase the efficiency and targeting range of cytidine base editors

Authors: Yuqiang Qian, Fengjiao Hui, Wenchao Niu, Di Wang, Yang Hao, Qingying Meng, Siyu Ren, Deqiang Kong, Heng Gong, Jiayu Wu, Kexin Chen, Muna Alariqi, Junping Gao, Zhanjun Li, Shuangxia Jin

Journal: Genome biology

PubMed ID: 41250247

Doi: doi.org/10.1186/s13059-025-03849-3

Products & Services: GenParts™ DNA Fragments

Potential of ferulic acid as a food-derived cardioprotective agent targeting mitochondrial dysfunction

Authors: Duanrui Cao, Lina Huang, Xiaowei Lu, Junhua Meng, Wenhong Li, Delin Duan, Qianqian Wang, Cuiping Liu, Zidong Qiu, Ni Zhang

Journal: Food Bioscience

Doi: //doi.org/10.1016/j.fbio.2025.107704

Products & Services: Custom DNA/RNA Oligos

SmallTalk: a novel small-sized fusion tag for peptide expression and purification

Authors: Atika Tariq, Nestor G Casillas-Vega, Alma Gomez-Loredo, Xristo Zarate

Journal: FEBS Open Bio

PubMed ID: 41220226

Doi: 10.1002/2211-5463.70147

Products & Services: Gene Synthesis

Glycosaminoglycans activate peptidylarginine deiminase 4 by enhancing calcium affinity

Authors: Grzegorz P. Bereta， Ewa Bielecka， Karolina Marzec， Łukasz Pijanowski， Artur P. Biela， Piotr Wilk， Marta Kamińska， Jakub Nowak， Elżbieta Wątor-Wilk， Przemysław Grudnik， Dominik Kowalczyk， Joanna Kozieł， Piotr Mydel， Marcin Poręba， Tomasz Kantyka

Journal: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

PubMed ID: 41166417

Doi: doi.org/10.1073/pnas.2508369122

Products & Services: Gene Synthesis

Structural insights into antagonist recognition by the vasopressin V2 receptor

Authors: Tianwei Zhang, Hongli Liu, Chongzhao You, Yixiao Zhang, Youwei Xu, Benxun Pan, Canrong Wu, Sanshan Jin, Yu-Ling Yin, Kai Wu, Yue Chen, Hong Sun, Yuan Si, Yangxia Tan, Wanchao Yin, H Eric Xu, Dong Guo, Yi Jiang

Journal: Nature Communications

PubMed ID: 41188237

Doi: 10.1038/s41467-025-64735-x

Products & Services: Proteins, Expression, Isolation and Analysis

A novel low-cost and sensitive electrochemical biosensor based on Yb-protein/GO/SPE for rare earth element detection

Authors: Ting Zhang, Danni Ma, Jiaxing Gong, Bolun Sun, Fuman Cai

Journal: Sustainable Chemistry and Pharmacy

Doi: doi.org/10.1016/j.scp.2025.102248

Products & Services: Molecular Biology Reagents

De novo designed voltage-gated anion channels suppress neuron firing

Authors: Chen Zhou, Huican Li, Jiaxing Wang, Cheng Qian, Hui Xiong, Zhilin Chu, Qiming Shao, Xuan Li, Shijin Sun, Ke Sun, Aiqin Zhu, Jiawei Wang, Xueqin Jin, Fan Yang, Tamer M Gamal El-Din, Bo Li, Jing Huang, Kun Wu, Peilong Lu

Journal: Cell

PubMed ID: 41106381

Doi: 10.1016/j.cell.2025.09.023

Products & Services: Proteins, Expression, Isolation and Analysis

Arzanol Inhibits Human Dihydroorotate Dehydrogenase and Shows Antiviral Activity

Authors: Marta Alberti, Martina Tamburello, Stefano Salamone, Giorgio Gallinella, Cinzia Sanna, Giovanni Battista Appendino, Marco L Lolli, Alberto Massarotti, Federica Pollastro, Riccardo Miggiano

Journal: Journal of natural products

PubMed ID: 41143446

Doi: 10.1021/acs.jnatprod.5c00887

Products & Services: PCR Cloning and Subcloning

Structural basis for 3C and 3CD recruitment by enteroviral genomes during negative-strand RNA synthesis

Authors: Naba Krishna Das, Alisha Patel, Reem Abdelghani, Deepak Koirala

Journal: Nature Communications

PubMed ID: 41120315

Doi: doi.org/10.1038/s41467-025-64376-0

Products & Services: Codon Optimization PCR Cloning and Subcloning

Simultaneous Monitoring of Intracellular Glucose and Extracellular Lactate in Single Cells to Assess Cell Tumorigenicity

Authors: Hui Liu, Yu Liu, Songqin Liu, Yafeng Wu

Journal: Analytical chemistry

PubMed ID: 41035132

Doi: 10.1021/acs.analchem.5c03740

Products & Services: Recombinant Proteins