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Nonclinical Evaluation of Single-Mutant Asparaginases Obtained by Double-Mutant Deconvolution: Improving Toxicological, Immune and Inflammatory Responses

Authors: Grace Ruiz-Lara, Tales A Costa-Silva, Jorge Javier Muso-Cachumba, Johanna Cevallos Espinel, Marina Gabriel Fontes, Mitla Garcia-Maya, Khondaker Miraz Rahman, Carlota de Oliveira Rangel-Yagui, Gisele Monteiro

Journal: Int J Mol Sci

PubMed ID: 38892196

Doi: 10.3390/ijms25116008

Products & Services: Codon Optimization

Podocyte Pathogenic Bone Morphogenetic Protein-2 Pathway and Immune Cell Behaviors in Primary Membranous Nephropathy

Authors: Anxiang Cai, Yiwei Meng, Hang Zhou, Hong Cai, Xinghua Shao, Qin Wang, Yao Xu, Yin Zhou, Wenyan Zhou, Luonan Chen, Shan Mou

Journal: Adv Sci (Weinh)

PubMed ID: 38785168

Doi: 10.1002/advs.202404151

Products & Services: Protein and Antibody Isolation

Oriented immobilization of antibodies through peptide ligands for ultrasensitive detection of gastrin 17 in human serum via lateral flow immunoassay

Authors: Xintong Li , Jiale Cui , Jin Li , Yulian Wang , Guoqing Shi

Journal: Microchemical Journal

Doi: j.microc.2024.110819

Products & Services: Peptide Synthesis

Staphylococcal peroxidase inhibitor (SPIN): Residue-level investigation of the helical bundle domain

Authors: Soheila Fatehi, Timothy J Herdendorf, Nicoleta T Ploscariu, Brian V Geisbrecht

Journal: Arch Biochem Biophys

PubMed ID: 38705227

Doi: 10.1016/j.abb.2024.110023

Products & Services: Molecular Biology Reagents

Establishment of an ELISA Based on a Recombinant Antigenic Protein Containing Multiple Prominent Epitopes for Detection of African Swine Fever Virus Antibodies

Authors: Dossêh Jean Apôtre Afayibo, Zhonghui Zhang, Hualin Sun, Jingsheng Fu, Yaru Zhao, Tharheer Oluwashola Amuda, Mengli Wu, Junzheng Du, Guiquan Guan, Qingli Niu, Jifei Yang, Hong Yin

Journal: Microorganisms

PubMed ID: 38792774

Doi: 10.3390/microorganisms12050943

Products & Services: Catalog Antibodies

Preparation and epitope analysis of monoclonal antibodies against African swine fever virus DP96R protein

Authors: Chao Li, Xuan-Ying Si, Xiao-Ge Wang, Zhi-Wei Yan, Hao-Yu Hou, Long-Qi You, Yin-Long Chen, Ang-Ke Zhang, Na Wang, Ai-Jun Sun, Yong-Kun Du, Gai-Ping Zhang

Journal: BMC Vet Res

PubMed ID: 38734611

Doi: 10.1186/s12917-024-04043-6

Products & Services: Gene Synthesis

Ser/Leu-swapped cell-free translation system constructed with natural/in vitro transcribed-hybrid tRNA set

Authors: Tomoshige Fujino, Ryogo Sonoda, Taito Higashinagata, Emi Mishiro-Sato, Keiko Kano, Hiroshi Murakami

Journal: Nat Commun

PubMed ID: 38755134

Doi: 10.1038/s41467-024-48056-z

Products & Services: Peptide Synthesis

A novel mouse model for investigating α-synuclein aggregates in oligodendrocytes: implications for the glial cytoplasmic inclusions in multiple system atrophy

Authors: Tomoyuki Ishimoto, Miki Oono, Seiji Kaji, Takashi Ayaki, Katsuya Nishida, Itaru Funakawa, Takakuni Maki, Shu-Ichi Matsuzawa, Ryosuke Takahashi, Hodaka Yamakado

Journal: Mol Brain

PubMed ID: 38790036

Doi: 10.1186/s13041-024-01104-7

Products & Services: Molecular Biology Reagents

Tracking single-cell evolution using clock-like chromatin accessibility loci

Authors: Yu Xiao, Wan Jin, Lingao Ju, Jie Fu, Gang Wang, Mengxue Yu, Fangjin Chen, Kaiyu Qian, Xinghuan Wang & Yi Zhang

Journal: Nature Biotechnol

PubMed ID: 38724668

Doi: 10.1038/s41587-024-02241-z

Products & Services: Synthetic Guide RNA

Computational design of non-porous pH-responsive antibody nanoparticles

Authors: Erin C. Yang, Robby Divine, Marcos C. Miranda, Andrew J. Borst, Will Sheffler, Jason Z. Zhang, Justin Decarreau, Amijai Saragovi, Mohamad Abedi, Nicolas Goldbach, Maggie Ahlrichs, Craig Dobbins, Alexis Hand, Suna Cheng, Mila Lamb, Paul M. Levine, Sidney Chan, Rebecca Skotheim, Jorge Fallas, George Ueda, Joshua Lubner, Masaharu Somiya, Alena Khmelinskaia, Neil P. King & David Baker

Journal: Nat Struct Mol Biol

PubMed ID: 38724718

Doi: 10.1038/s41594-024-01288-5

Products & Services: Gene Synthesis