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HTRA1 disaggregates α-synuclein amyloid fibrils and converts them into non-toxic and seeding incompetent species

Authors: Sheng Chen, Anuradhika Puri, Braxton Bell, Joseph Fritsche, Hector H Palacios, Maurie Balch, Macy L Sprunger, Matthew K Howard, Jeremy J Ryan, Jessica N Haines, Gary J Patti, Albert A Davis, Meredith E Jackrel

Journal: Nat Commun

PubMed ID: 38499535

Doi: 10.1038/s41467-024-46538-8

Products & Services: Molecular Biology Reagents

Construction of recombinant pseudorabies virus expressing PCV2 Cap, PCV3 Cap, and IL-4: investigation of their biological characteristics and immunogenicity

Authors: Yanting Yang, Zhiwen Xu, Qian Tao, Lei Xu, Sirui Gu, Yao Huang, Zheyan Liu, Yang Zhang, Jianhua Wen, Siyuan Lai, Ling Zhu

Journal: Front Immunol

PubMed ID: 38571947

Doi: 10.3389/fimmu.2024.1339387

Products & Services: Molecular Biology Reagents

Expanding the molecular language of protein liquid-liquid phase separation

Authors: Shiv Rekhi, Cristobal Garcia Garcia, Mayur Barai, Azamat Rizuan, Benjamin S Schuster, Kristi L Kiick, Jeetain Mittal

Journal: Nat Chem

PubMed ID: 38553587

Doi: 10.1038/s41557-024-01489-x

Products & Services: Molecular Biology Reagents

LysSYL: a broad-spectrum phage endolysin targeting Staphylococcus species and eradicating S aureus biofilms

Authors: He Liu, Xuemei Wei, Zhefen Wang, Xiaonan Huang, Mengyang Li, Zhen Hu, Kexin Zhang, Qiwen Hu, Huagang Peng, Weilong Shang, Yi Yang, Yuting Wang, Shuguang Lu, Xiancai Rao

Journal: Microb Cell Fact

PubMed ID: 38528536

Doi: 10.1186/s12934-024-02359-4

Products & Services: Molecular Biology Reagents

Self-adaptive pyroptosis-responsive nanoliposomes block pyroptosis in autoimmune inflammatory diseases

Authors: Kaiwang Xu, Huang Yang, Jinghua Fang, Kaijie Qiu, Haotian Shen, Guanrui Huang, Qiangqiang Zheng, Canlong Wang, Tengjing Xu, Xinning Yu, Jiajie Wang, Yunting Lin, Jiacheng Dai, Yuting Zhong, Hongyun Song, Sunan Zhu, Siheng Wang, Zhuxing Zhou, Guang Yang, Zhengwei Mao, Zongyou Pan, Xuesong Dai

Journal: Bioactive Materials

PubMed ID: 38496034

Doi: 10.1016/j.bioactmat.2024.02.022

Products & Services: Bacterial Expression Mammalian Expression

Interferon-γ in the tumor microenvironment promotes the expression of B7H4 in colorectal cancer cells, thereby inhibiting cytotoxic T cells

Authors: Zhi-Liang Jing, Guang-Long Liu, Na Zhou, Dong-Yan Xu, Na Feng, Yan Lei, Li-Li Ma, Min-Shan Tang, Gui-Hui Tong, Na Tang, Yong-Jian Deng

Journal: Nature

PubMed ID: 38480774

Doi: 10.1038/s41598-024-56681-3

Products & Services: Polyclonal Antibody Services

Molecular basis for substrate transport of Mycobacterium tuberculosis ABC importer DppABCD

Authors: Tianyu Hu, Xiaolin Yang, Yuanchen Zhu, Fengjiang Liu, Xiuna Yang, Zhiqi Xiong, Jingxi Liang, Zhenli Lin, Yuting Ran, Luke W Guddat, Zihe Rao, Bing Zhang

Journal: SCIENCE ADVANCES

PubMed ID: 38507491

Doi: 10.1126/sciadv.adk8521

Products & Services: Protein and Antibody Isolation

MIWI N-terminal arginines orchestrate generation of functional pachytene piRNAs and spermiogenesis

Authors: Nicholas Vrettos, Jan Oppelt, Ansgar Zoch, Paraskevi Sgourdou, Haruka Yoshida, Brian Song, Ryan Fink, Dónal O'Carroll, Zissimos Mourelatos 1

Journal: Nucleic Acids Research

PubMed ID: 38520410

Doi: 10.1093/nar/gkae193

Products & Services: Peptide Synthesis

Zoledronic Acid Accelerates ER Stress-Mediated Inflammation by Increasing PDE4B Expression in Bisphosphonate-Related Osteonecrosis of the Jaw

Authors: Qu Xz, Sun Zq, Liu L, Ong Hs

Journal: Appl Biochem Biotechnol

PubMed ID: 38523176

Doi: 10.1007/s12010-024-04859-w

Products & Services: Gene Synthesis

Supra-biological performance of immobilized enzymes enabled by chaperone-like specific non-covalent interactions

Authors: Héctor Sánchez-Morán, Joel L Kaar, Daniel K Schwartz

Journal: Nat Commun

PubMed ID: 38485940

Doi: 10.1038/s41467-024-46719-5

Products & Services: Molecular Biology Reagents