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ER nests are specialized ER subdomains in Arabidopsis where peroxisomes and lipid droplets form

Authors: Zachary J Wright , Nathan E Tharp , Bonnie Bartel

Journal: Developmental Cell

Doi: 10.1016/j.devcel.2025.03.005

Products & Services: Gene Synthesis Protein Electrophoresis and Western

Active- and Allosteric-Site Cyclic Peptide Inhibitors of Secreted M. tuberculosis Chorismate Mutase

Authors: Renier H P van Neer, Patricia K Dranchak, Mahesh Aitha, Lijun Liu, Emma K Carlson, Isabella E Jacobsen, Kevin Battaile, Yuhong Fang, Dingyin Tao, Ganesha Rai, Janak Padia, Scott Lovell, Hiroaki Suga, James Inglese

Journal: ACS Infectious Diseases

PubMed ID: 39903128

Doi: 10.1021/acsinfecdis.4c00798

Products & Services: Peptide Synthesis Plasmid DNA Preparation

Potential role of TRAF2 in pulmonary hypertension in broiler chickens and preparation and specificity analysis of its polyclonal antibody

Authors: Wen Peng, Gen Wan, Sufang Cheng, Guyue Li, Liling Liu, Juan Chen, Pei Liu, Xiaoquan Guo, Xiaona Gao, Gaofeng Cai, Zhanhong Zheng, Ping Liu

Journal: Int J Biol Macromol

PubMed ID: 39798767

Doi: doi.org/10.1016/j.ijbiomac.2025.139741

Products & Services: Protein Electrophoresis and Western

A coronavirus assembly inhibitor that targets the viral membrane protein

Authors: Manon Laporte; Dirk Jochmans; Doroth e Bardiot; Lowiese Desmarets; Oliver J. Debski-Antoniak; Giulia Mizzon; Rana Abdelnabi; Pieter Leyssen; Winston Chiu; Zhikuan Zhang; Norimichi Nomura; Sandro Boland; Umeharu Ohto; Yannick Stahl; Jurgen Wuyts; Steven De Jonghe; Annelies Stevaert; Martijn J. van Hemert; Brenda W. Bontes; Patrick Wanningen; G. J. Mirjam Groenewold; Aneta Zegar; Katarzyna Owczarek; Sanjata Joshi; Mohamed Koukni; Philippe Arzel; Hugo Klaassen; Jean-Christophe Vanherck; Ilse Vandecaetsbeek; Niels Cremers; Kim Donckers; Thibault Francken; Tina Van Buyten; Jasper Rymenants; Joost Schepers; Krzysztof Pyrc; Rolf Hilgenfeld; Jean Dubuisson; Berend-Jan Bosch; Frank Van Kuppeveld; Cecilia Eydoux; Etienne Decroly; Bruno Canard; Lieve Naesens; Birgit Weynand; Eric J. Snijder; Sandrine Belouzard; Toshiyuki Shimizu; Ralf Bartenschlager; Daniel L. Hurdiss; Arnaud Marchand; Patrick Chaltin; Johan Neyts

Journal: Nature

PubMed ID: 40140569

Doi: 10.1038/s41586-025-08773-x

A Modified Variant of Fasciola hepatica FhSAP-2 (mFhSAP-2) as a Recombinant Vaccine Candidate Induces High-Avidity IgG2c Antibodies and Enhances T Cell Activation in C57BL/6 Mice

Authors: Riseilly Ramos-Nieves; Albersy Armina-Rodriguez; Maria Del Mar Figueroa-Gispert; Ghalib Figueroa-Qui ones; Carlimar Ocasio-Malav ; Ana M. Espino

Journal: Vaccines

PubMed ID: 40432154

Doi: 10.3390/vaccines13050545

A Modified Variant of Fasciola hepatica FhSAP-2 (mFhSAP-2) as a Recombinant Vaccine Candidate Induces High-Avidity IgG2c Antibodies and Enhances T Cell Activation in C57BL/6 Mice

Authors: Riseilly Ramos-Nieves; Albersy Armina-Rodriguez; Maria Del Mar Figueroa-Gispert; Ghalib Figueroa-Qui ones; Carlimar Ocasio-Malav ; Ana M. Espino

Journal: Vaccines

PubMed ID: 40432154

Doi: 10.3390/vaccines13050545

De novo design of a two-step approach targeting Claudin-6 for enhanced drug delivery to solid tumors

Authors: Jiayao Yan; Liqing Zhong; Xiaotong Chen; Lin Li; Fangcen Liu; Lei Lei; Mengchao An; Xiao Wei; Ying Wang; Tianran Chen; Jingyi Guo; Jie Shao; Xiaoxiao Yu; Yingjie Zhao; Rutian Li; Qin Liu; Baorui Liu

Journal: Journal of translational medicine

PubMed ID: 41267074

Doi: 10.1186/s12967-025-07316-2

De novo design of a two-step approach targeting Claudin-6 for enhanced drug delivery to solid tumors

Journal: Journal of translational medicine

PubMed ID: 41267074

Doi: 10.1186/s12967-025-07316-2

Structural mechanisms underlying the modulation of CXCR4 by diverse small-molecule antagonists

Authors: Xiaohong Sang, Haizhan Jiao, Qian Meng, Xiong Fang, Qi Pan, Jiao Zhou, Tingli Qian, Wanqin Zhang, Yan Xu, Jing An, Ziwei Huang, Hongli Hu

Journal: Proceedings of the National Academy of Sciences of the United States of America

PubMed ID: 40063796

Doi: 10.1073/pnas.2425795122

Products & Services: Gene Synthesis

Large Library Docking for Polypharmacology

Authors: Yujin Wu; Seth Vigneron; Joao Braz; Karthik Srinivasan; Elissa A. Fink; Xi-Ping Huang; Xinyu Xu; Harald Huebner; Joseph Y. Kim; Jing Wang; Tara Pfeiffer; Kensuke Sakamoto; Dmytro S. Radchenko; Ramona M. Rodriguiz; Yurii S. Moroz; John J. Irwin; Peter Gmeiner; Christian Billesboelle; Bryan L. Roth; Allan I. Basbaum; Aashish Manglik; William C. Wetsel; Brian K. Shoichet

Journal: Journal of Medicinal Chemistry

PubMed ID: 41712624

Doi: 10.1021/acs.jmedchem.5c03810

Products & Services: Peptide Synthesis