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Microenvironment actuated CAR T cells improve solid tumor efficacy without toxicity

Authors: Kristen C Vogt , Pedro C Silberman , Qianqian Lin , James E Han , Amy Laflin , Hendryck A Gellineau , Daniel A Heller , David A Scheinberg

Journal: SCIENCE ADVANCES

PubMed ID: 39841845

Doi: 10.1126/sciadv.ads3403

Products & Services: Gene Synthesis

Direct repeat region 3’ end modifications regulate Cas12a activity and expand its applications

Authors: Wei Zhang , Yinyin Zhong , Jiaqi Wang , Guangrong Zou , Qiaozhen Chen , Chaoxing Liu

Journal: Nucleic Acids Res

PubMed ID: 39883010

Doi: 10.1093/nar/gkaf040

Products & Services: PCR Cloning and Subcloning

An Insect Eﬀector Mimics Its Host Immune Regulator to Undermine Plant Immunity

Authors: Jianmei Fu , Shuai Li , Jing Li , Zhichang Zhao , Jing Li , Xinyang Tan , Shan Yu , Maofeng Jing , Keyan Zhu-Salzman , Jichao Fang , Rui Ji

Journal: Adv Sci (Weinh)

PubMed ID: 39853648

Doi: doi.org/10.1002/advs.202409186

Products & Services: Peptide Synthesis

Light signal regulates endoreduplication and tomato fruit expansion through the SlPIF1a-SlTLFP8-SlCDKB2 module

Authors: Jiaojiao Zhang, Jiayi Xu, Xinman Wang, Ying Liu, Shuangtao Li, Jialong Zhang, Lingfeng He, Luqin Guo, Chonghua Li, Xin-Xu Li, Yang-Dong Guo, Na Zhang

Journal: Proceedings of the National Academy of Sciences of the United States of America

PubMed ID: 39847324

Doi: 10.1073/pnas.2404445122

Products & Services: Polyclonal Antibody Services

Evolving antibody response to SARS-CoV-2 antigenic shift from XBB to JN.1

Authors: Fanchong Jian, Jing Wang, Ayijiang Yisimayi, Weiliang Song, Yanli Xu, Xiaosu Chen, Xiao Niu, Sijie Yang, Yuanling Yu, Peng Wang, Haiyan Sun, Lingling Yu, Jing Wang, Yao Wang, Ran An, Wenjing Wang, Miaomiao Ma, Tianhe Xiao, Qingqing Gu, Fei Shao, Youchun Wang, Zhongyang Shen, Ronghua Jin, Yunlong Cao

Journal: Nature

PubMed ID: 39510125

Doi: 10.1038/s41586-024-08315-x

Products & Services: Gene Synthesis Codon Optimization

A high-fidelity CRISPR-Cas13 system improves abnormalities associated with C9ORF72-linked ALS/FTD

Authors: Tristan X. McCallister, Colin K. W. Lim, Mayuri Singh, Sijia Zhang, Najah S. Ahsan, William M. Terpstra, Alisha Y. Xiong, M. Alejandra Zeballos C, Jackson E. Powell, Jenny Drnevich, Yifei Kang & Thomas Gaj

Journal: Nature Communications

PubMed ID: 39779681

Doi: 10.1038/s41467-024-55548-5

Products & Services: Custom Vector Construction

Evolution of Omicron lineage towards increased fitness in the upper respiratory tract in the absence of severe lung pathology

Authors: Arthur Wickenhagen, Meaghan Flagg, Julia R. Port, Claude Kwe Yinda, Kerry Goldin, Shane Gallogly, Jonathan E. Schulz, Tessa Lutterman, Brandi N. Williamson, Franziska Kaiser, Reshma K. Mukesh, Sarah van Tol, Brian Smith, Neeltje van Doremalen, Colin A. Russell, Emmie de Wit & Vincent J. Munster

Journal: Nature Communications

PubMed ID: 39799119

Doi: 10.1038/s41467-025-55938-3

Products & Services: Gene Synthesis

Divergent evolution of opposite base specificity and single-stranded DNA activity in animal and plant AP endonucleases

Authors: Marina Jordano-Raya, Carol E Schrader, Rafael R Ariza, Teresa Roldán-Arjona, Dolores Córdoba-Cañero

Journal: Nucleic Acids Research

PubMed ID: 39778867

Doi: 10.1093/nar/gkae1297

Products & Services: Codon Optimization

IL-33-activated ILC2s induce tertiary lymphoid structures in pancreatic cancer

Authors: Masataka Amisaki, Abderezak Zebboudj, Hiroshi Yano, Siqi Linsey Zhang, George Payne, Adrienne Kaya Chandra, Rebecca Yu, Pablo Guasp, Zachary M. Sethna, Akihiro Ohmoto, Luis A. Rojas, Charlotte Cheng, Theresa Waters, Alexander Solovyov, Stephen Martis, Ashley S. Doane, Charlotte Reiche, Emmanuel M. Bruno, Martina Milighetti, Kevin Soares, Zagaa Odgerel, John Alec Moral, Julia N. Zhao, Mithat Gönen, …Vinod P. Balachandran

Journal: Nature

PubMed ID: 39814891

Doi: 10.1038/s41586-024-08426-5

Products & Services: Recombinant Proteins

Rapid and comprehensive detection of viral antibodies and nucleic acids via an acoustofluidic integrated molecular diagnostics chip: AIMDx

Authors: Jiao Qian , Jianping Xia , Samantha Chiang , Jessica F Liu , Ke Li , Feng Li , Fang Wei , Mohammad Aziz , Yong Kim , Vinson Go , James Morizio , Ruoyu Zhong , Ye He , Kaichun Yang , Otto O Yang , David T W Wong , Luke P Lee , Tony Jun Huang

Journal: SCIENCE ADVANCES

PubMed ID: 39813350

Doi: 10.1126/sciadv.adt5464