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Dexmedetomidine enhances Mitophagy via PINK1 to alleviate hippocampal neuronal Pyroptosis and improve postoperative cognitive dysfunction in elderly rat

Authors: Yayu Chen, Gen Wei, Lieliang Zhang, Xiaojin Feng, Enjun Lei

Journal: Exp Neurol

PubMed ID: 38823674

Doi: 10.1016/j.expneurol.2024.114842

Products & Services: Gene Synthesis

Distinct components of nucleoside-modified messenger RNA vaccines cooperate to instruct efficient germinal center responses

Authors: Emily Bettini, Aleksey Chudnovskiy, Giulia Protti, Sandra Nakadakari-Higa, Simona Ceglia, Diana Castaño, Joy Chiu, Hiromi Muramatsu, Thandiswa Mdluli, Edit Abraham, Zoltan Lipinszki, Ivan Maillard, Ying K Tam, Andrea Reboldi, Norbert Pardi, Roberto Spreafico, Gabriel D Victora, Michela Locci

Journal: biorxiv

PubMed ID: 38798523

Doi: 10.1101/2024.05.17.594726

Products & Services: Gene Synthesis

Kinetic Characterization and Identification of Key Active Site Residues of the L-Aspartate N-Hydroxylase, CreE

Authors: Sydney B Johnson, Hannah Valentino, Pablo Sobrado

Journal: Chembiochem

PubMed ID: 38775737

Doi: 10.1002/cbic.202400350

Products & Services: Molecular Biology Reagents

Structural Determinants of FeoB Nucleotide Promiscuity

Authors: Mark Lee, Kate Magante, Camilo Gómez-Garzón, Shelley M Payne, Aaron T Smith

Journal: biorxiv

PubMed ID: 38826458

Doi: 10.1101/2024.05.22.595361

Products & Services: Protein and Antibody Isolation

Staphylococcal peroxidase inhibitor (SPIN): Residue-level investigation of the helical bundle domain

Authors: Soheila Fatehi, Timothy J Herdendorf, Nicoleta T Ploscariu, Brian V Geisbrecht

Journal: Arch Biochem Biophys

PubMed ID: 38705227

Doi: 10.1016/j.abb.2024.110023

Products & Services: Molecular Biology Reagents

Establishment of an ELISA Based on a Recombinant Antigenic Protein Containing Multiple Prominent Epitopes for Detection of African Swine Fever Virus Antibodies

Authors: Dossêh Jean Apôtre Afayibo, Zhonghui Zhang, Hualin Sun, Jingsheng Fu, Yaru Zhao, Tharheer Oluwashola Amuda, Mengli Wu, Junzheng Du, Guiquan Guan, Qingli Niu, Jifei Yang, Hong Yin

Journal: Microorganisms

PubMed ID: 38792774

Doi: 10.3390/microorganisms12050943

Products & Services: Catalog Antibodies

Preparation and epitope analysis of monoclonal antibodies against African swine fever virus DP96R protein

Authors: Chao Li, Xuan-Ying Si, Xiao-Ge Wang, Zhi-Wei Yan, Hao-Yu Hou, Long-Qi You, Yin-Long Chen, Ang-Ke Zhang, Na Wang, Ai-Jun Sun, Yong-Kun Du, Gai-Ping Zhang

Journal: BMC Vet Res

PubMed ID: 38734611

Doi: 10.1186/s12917-024-04043-6

Products & Services: Gene Synthesis

Ser/Leu-swapped cell-free translation system constructed with natural/in vitro transcribed-hybrid tRNA set

Authors: Tomoshige Fujino, Ryogo Sonoda, Taito Higashinagata, Emi Mishiro-Sato, Keiko Kano, Hiroshi Murakami

Journal: Nat Commun

PubMed ID: 38755134

Doi: 10.1038/s41467-024-48056-z

Products & Services: Peptide Synthesis

A novel mouse model for investigating α-synuclein aggregates in oligodendrocytes: implications for the glial cytoplasmic inclusions in multiple system atrophy

Authors: Tomoyuki Ishimoto, Miki Oono, Seiji Kaji, Takashi Ayaki, Katsuya Nishida, Itaru Funakawa, Takakuni Maki, Shu-Ichi Matsuzawa, Ryosuke Takahashi, Hodaka Yamakado

Journal: Mol Brain

PubMed ID: 38790036

Doi: 10.1186/s13041-024-01104-7

Products & Services: Molecular Biology Reagents

Tracking single-cell evolution using clock-like chromatin accessibility loci

Authors: Yu Xiao, Wan Jin, Lingao Ju, Jie Fu, Gang Wang, Mengxue Yu, Fangjin Chen, Kaiyu Qian, Xinghuan Wang & Yi Zhang

Journal: Nature Biotechnol

PubMed ID: 38724668

Doi: 10.1038/s41587-024-02241-z

Products & Services: Synthetic Guide RNA