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TET2-mediated ECM1 hypomethylation promotes the neovascularization in active proliferative diabetic retinopathy

Authors: Chunyang Cai, Chufeng Gu, Shuai He, Chunren Meng, Dongwei Lai, Jingfa Zhang, Qinghua Qiu

Journal: Clinical epigenetics

PubMed ID: 38172938

Doi: 10.1186/s13148-023-01619-1

Products & Services: Protein and Antibody Isolation

Biochemical and structural characterization of Rab3GAP reveals insights into Rab18 nucleotide exchange activity

Authors: Gage M. J. Fairlie, Kha M. Nguyen, Sung-Eun Nam, Alexandria L. Shaw, Matthew A. H. Parson, Hannah R. Shariati, Xinyin Wang, Meredith L. Jenkins, Michael Gong, John E. Burke & Calvin K. Yip

Journal: Nature Communications

PubMed ID: 39779760

Doi: 10.1038/s41467-025-55828-8

Products & Services: Protein and Antibody Isolation

Interplay between the Xer recombination system and the dissemination of antibioresistance in Acinetobacter baumannii

Authors: Corentin Blanchais, Carine Pages, Manuel Campos, Kenza Boubekeur, Rachel Contarin, Mathias Orlando, Patricia Siguier, Maria-Halima Laaberki, François Cornet, Xavier Charpentier, Philippe Rousseau

Journal: Nucleic Acids Research

PubMed ID: 39777461

Doi: 10.1093/nar/gkae1255

Products & Services: Gene Synthesis

Structural dynamics of calcium and integrin-binding protein 2 (CIB2) reveal uncommon flexibility and heterogeneous calcium and magnesium loading

Authors: Gabriele Olivieri, Giuditta Dal Cortivo, Rebecca Del Conte, Serena Zanzoni, Valerio Marino, Daniele Dell'Orco, Francesca Cantini

Journal: International Journal of Biological Macromolecules

PubMed ID: 39586446

Doi: doi.org/10.1016/j.ijbiomac.2024.138003

Products & Services: Peptide Synthesis

Intestine-Decipher Engineered Capsules Protect Against Sepsis-induced Intestinal Injury via Broad-spectrum Anti-inflammation and Parthanatos Inhibition

Authors: Yan Yan, Bin Li, Qiuxia Gao, Miao Wu, Hua Ma, Jiawei Bai, Chengtai Ma, Xinyu Xie, Yuan Gong, Lingqi Xu, Xiaoxue Li, Wei Wang, Yanqiu Wu, Jiamei Wang, Huanhuan Wang, Yi Feng, Yunlong Zhang, Peiran Li, Huimin Shi, Fei Ma, Yue Jia, Han Duan, Xinting Fu, Wenying Wang, Liying Zhan, Xianjin Du, Huiting Zhou, Yuhui Liao

Journal: Advanced Science

PubMed ID: 39836501

Doi: 10.1002/advs.202412799

Products & Services: Protein Electrophoresis and Western

Dynamic allostery in the peptide/MHC complex enables TCR neoantigen selectivity

Authors: Jiaqi Ma, Cory M. Ayres, Chad A. Brambley, Smita S. Chandran, Tatiana J. Rosales, W. W. J. Gihan Perera, Bassant Eldaly, William T. Murray, Steven A. Corcelli, Evgenii L. Kovrigin, Christopher A. Klebanoff & Brian M. Baker

Journal: Nature Communications

PubMed ID: 39833157

Doi: 10.1038/s41467-025-56004-8

Products & Services: Neoantigen Peptide Service

Influenza A Virus H7 nanobody recognizes a conserved immunodominant epitope on hemagglutinin head and confers heterosubtypic protection

Authors: Zhao-Shan Chen, Hsiang-Chi Huang, Xiangkun Wang, Karin Schön, Yane Jia, Michael Lebens, Danica F. Besavilla, Janarthan R. Murti, Yanhong Ji, Aishe A. Sarshad, Guohua Deng, Qiyun Zhu & Davide Angeletti

Journal: Nature Communications

PubMed ID: 39788944

Doi: 10.1038/s41467-024-55193-y

Products & Services: Catalog Antibodies

Identification of a binding site for small molecule inhibitors targeting human TRPM4

Authors: Babatunde Ekundayo, Prakash Arullampalam, Christian E. Gerber, Anne-Flore Hämmerli, Sabrina Guichard, Mey Boukenna, Daniela Ross-Kaschitza, Martin Lochner, Jean-Sebastien Rougier, Henning Stahlberg, Hugues Abriel & Dongchun Ni

Journal: Nature Communications

PubMed ID: 39828793

Doi: 10.1038/s41467-025-56131-2

Products & Services: Mutagenesis Services

Barcoded SARS-CoV-2 viruses define the impact of duration and route of exposure on the transmission bottleneck in a hamster model

Authors: Reed Trende , Tamarand L Darling , Tianyu Gan , David Wang , Adrianus C M Boon

Journal: SCIENCE ADVANCES

PubMed ID: 39813353

Doi: 10.1126/sciadv.ads2927

Products & Services: Gene Synthesis

Microenvironment actuated CAR T cells improve solid tumor efficacy without toxicity

Authors: Kristen C Vogt , Pedro C Silberman , Qianqian Lin , James E Han , Amy Laflin , Hendryck A Gellineau , Daniel A Heller , David A Scheinberg

Journal: SCIENCE ADVANCES

PubMed ID: 39841845

Doi: 10.1126/sciadv.ads3403

Products & Services: Gene Synthesis