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IL-9/STAT3/fatty acid oxidation-mediated lipid peroxidation contributes to Tc9 cell longevity and enhanced antitumor activity
Authors: Liuling Xiao, Xingzhe Ma, Lingqun Ye, Pan Su, Wei Xiong, Enguang Bi, Qiang Wang, Miao Xian, Maojie Yang, Jianfei Qian, Qing Yi
Journal: J Clin Invest
PubMed ID: 35192544
Doi: 10.1172/JCI153247
Products & Services: Catalog Peptides   
IL-4 plays an essential role in DnaJ-ΔA146Ply-mediated immunoprotection against Streptococcus pneumoniae in mice
Authors: Yi Hu, Lian Li, Wenchun Xu, Kaifeng Wu, Jiangming Xiao, Yang Peng, Yusi Liu, Yibing Yin, Xuemei Zhang
Journal: Mol Immunol
PubMed ID: 35114487
Doi: 10.1016/j.molimm.2022.01.010
Products & Services: Endotoxin Detection & Removal System   
A Novel CD3/BCMA Bispecific T-cell Redirecting Antibody for the Treatment of Multiple Myeloma
Authors: Mengshang Xiong, Ruoqi Liu, Xiaomin Lei, Dongmei Fan, Fangzhen Lin, Wei Hao, Xiangfei Yuan, Yuanyuan Yang, Xiaolong Zhang, Zhou Ye, Yang Lu, Yanjun Zhang, Jianxiang Wang, Dongsheng Xiong
Journal: J Immunother
PubMed ID: 34711791
Doi: 10.1097/CJI.0000000000000401
Products & Services: Proteins, Expression, Isolation and Analysis   
RNA interference targeting UL25 gene as a gene therapy approach against BHV-1
Authors: Elaheh Amjadimanesh, Azam Mokhtari, Behnaz Saffar
Journal: Res Vet Sci
PubMed ID: 35182967
Doi: 10.1016/j.rvsc.2022.02.007
Products & Services: Custom DNA/RNA Oligos   
Receptor tyrosine kinases regulate signal transduction through a liquid-liquid phase separated state
Authors: Chi-Chuan Lin, Kin Man Suen, Polly-Anne Jeffrey, Lukasz Wieteska, Jessica A Lidster, Peng Bao, Alistair P Curd, Amy Stainthorp, Caroline Seiler, Hans Koss, Eric Miska, Zamal Ahmed, Stephen D Evans, Carmen Molina-París, John E Ladbury
Journal: Mol Cell
PubMed ID: 35231400
Doi: 10.1016/j.molcel.2022.02.005
Products & Services: Peptide Synthesis   
Ligand-directed bias of G protein signaling at the dopamine D2 receptor
Authors: Ee Von Moo , Kasper Harpsøe , Alexander S Hauser , Ikuo Masuho , Hans Bräuner-Osborne , David E Gloriam , Kirill A Martemyanov
Journal: Cell Chem Biol .
PubMed ID: 34302750
Doi: 10.1016/j.chembiol.2021.07.004
Products & Services: Mutagenesis Services   Gene Synthesis   
SARS-CoV-2 Variants Increase Kinetic Stability of Open Spike Conformations as an Evolutionary Strategy
Authors: Ziwei Yang, Yang Han, Shilei Ding, Wei Shi, Tongqing Zhou, Andrés Finzi, Peter D Kwong, Walther Mothes, Maolin Lu
Journal: MBio
PubMed ID: 35164561
Doi: 10.1128/mbio.03227-21
Products & Services: Gene Synthesis   
Germinal centre-driven maturation of B cell response to mRNA vaccination
Authors: Wooseob Kim, Julian Q Zhou, Stephen C Horvath, Aaron J Schmitz, Alexandria J Sturtz, Tingting Lei, Zhuoming Liu, Elizaveta Kalaidina, Mahima Thapa, Wafaa B Alsoussi, Alem Haile, Michael K Klebert, Teresa Suessen, Luis Parra-Rodriguez, Philip A Mudd, Sean P J Whelan, William D Middleton, Sharlene A Teefey, Iskra Pusic, Jane A O'Halloran, Rachel M Presti, Jackson S Turner, Ali H Ellebedy
Journal: Nature
PubMed ID: 35168246
Doi: 10.1038/s41586-022-04527-1
Products & Services: Plasmid DNA Preparation   
Disentangling the recognition complexity of a protein hub using a nanopore
Authors: Lauren Ashley Mayse, Ali Imran, Motahareh Ghahari Larimi, Michael S Cosgrove, Aaron James Wolfe, Liviu Movileanu
Journal: Nat Commun
PubMed ID: 35190547
Doi: 10.1038/s41467-022-28465-8
Products & Services: Plasmid DNA Preparation   
Mutant glucocerebrosidase impairs α-synuclein degradation by blockade of chaperone-mediated autophagy
Authors: Sheng-Han Kuo, Inmaculada Tasset, Melody M Cheng, Antonio Diaz, Ming-Kai Pan, Ori J Lieberman, Samantha J Hutten, Roy N Alcalay, Sangjun Kim, Pilar Ximénez-Embún, Li Fan, Donghoon Kim, Han Seok Ko, Talene Yacoubian, Ellen Kanter, Ling Liu, Guomei Tang, Javier Muñoz, Sergio Pablo Sardi, Aiqun Li, Li Gan, Ana Maria Cuervo, David Sulzer
Journal: Sci Adv
PubMed ID: 35138901
Doi: 10.1126/sciadv.abm6393
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