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Structure and engineering of the minimal type VI CRISPR-Cas13bt3
Authors: Ryoya Nakagawa, Soumya Kannan, Han Altae-Tran, Satoru N Takeda, Atsuhiro Tomita, Hisato Hirano, Tsukasa Kusakizako, Tomohiro Nishizawa, Keitaro Yamashita, Feng Zhang, Hiroshi Nishimasu, Osamu Nureki
Journal: Mol Cell
PubMed ID: 36027912
Doi: 10.1016/j.molcel.2022.08.001
Products & Services: Synthetic sgRNA and crRNA Service   
Impact of SARS-CoV-2 Spike Mutations on Its Activation by TMPRSS2 and the Alternative TMPRSS13 Protease
Authors: Annelies Stevaert, Ria Van Berwaer, Cato Mestdagh, Julie Vandeput, Els Vanstreels, Valerie Raeymaekers, Manon Laporte, Lieve Naesens
Journal: MBio
PubMed ID: 35913162
Doi: 10.1128/mbio.01376-22
Products & Services: Proteins, Expression, Isolation and Analysis   
TCR extracellular domain genetically linked to CD28, 2B4/41BB and DAP10/CD3ζ -engineered NK cells mediates antitumor effects
Authors: Shance Li, Chaoting Zhang, Luyan Shen, Xia Teng, Yefei Xiao, Bentong Yu, Zheming Lu
Journal: Cancer Immunol Immunother
PubMed ID: 35988132
Doi: 10.1007/s00262-022-03275-5
Products & Services: Custom Vector Construction   
SARS-CoV-2 in a Mink Farm in Italy: Case Description, Molecular and Serological Diagnosis by Comparing Different Tests
Authors: Ana Moreno, Davide Lelli, Tiziana Trogu, Antonio Lavazza, Ilaria Barbieri, MariaBeatrice Boniotti, Giulia Pezzoni, Cristian Salogni, Stefano Giovannini, Giovanni Alborali, Silvia Bellini, Massimo Boldini, Marco Farioli, Luigi Ruocco, Olivia Bessi, Andrea Maroni Ponti, Ilaria Di Bartolo, Luca De Sabato, Gabriele Vaccari, Gabriele Belli, Alberto Margutti, Maurilio Giorgi
Journal: Viruses
PubMed ID: 36016360
Doi: 10.3390/v14081738
Products & Services: Recombinant Proteins   
Allosteric modulation of GPCR-induced β-arrestin trafficking and signaling by a synthetic intrabody
Authors: Mithu Baidya, Madhu Chaturvedi, Hemlata Dwivedi-Agnihotri, Ashutosh Ranjan, Dominic Devost, Yoon Namkung, Tomasz Maciej Stepniewski, Shubhi Pandey, Minakshi Baruah, Bhanupriya Panigrahi, Parishmita Sarma, Manish K Yadav, Jagannath Maharana, Ramanuj Banerjee, Kouki Kawakami, Asuka Inoue, Jana Selent, Stéphane A Laporte, Terence E Hébert, Arun K Shukla
Journal: Nat Commun
PubMed ID: 35941121
Doi: 10.1038/s41467-022-32386-x
Products & Services: Peptide Synthesis   
Immunoprophylaxis using polypeptide chimera vaccines plus adjuvant system promote Th1 response controlling the spleen parasitism in hamster model of visceral leishmaniasis
Authors: Miriã Rodrigues Gusmão, Thaís Lopes Valentim Di Paschoali Ostolin, Lívia Mendes Carvalho, Ana Flávia Pereira Costa, Gabriel José Lucas Moreira, Jamille Mirelle de Oliveira Cardoso, Rodrigo Dian de Oliveira Aguiar-Soares, Alexandre Barbosa Reis, Rory Cristiane Fortes de Brito, Bruno Mendes Roatt
Journal: Vaccine
PubMed ID: 35963820
Doi: 10.1016/j.vaccine.2022.08.005
Products & Services: Custom Vector Construction   
Ubiquitination at the lysine 27 residue of the Parkin ubiquitin-like domain is suggestive of a new mechanism of Parkin activation
Authors: Jun-Yi Liu, Tsuyoshi Inoshita, Kahori Shiba-Fukushima, Shigeharu Yoshida, Kosuke Ogata, Yasushi Ishihama, Yuzuru Imai, Nobutaka Hattori
Journal: Hum Mol Genet
PubMed ID: 35313349
Doi: 10.1093/hmg/ddac064
Products & Services: Mutagenesis Services   
Neuroprotection of Bone Marrow-Derived Mesenchymal Stem Cell-Derived Extracellular Vesicle-Enclosed miR-410 Correlates with HDAC4 Knockdown in Hypoxic-Ischemic Brain Damage
Authors: Mingqi Shen, Rongxiu Zheng, Xuan Kan
Journal: Neurochem Res
PubMed ID: 36028735
Doi: 10.1007/s11064-022-03670-5
Products & Services: Mutant Libraries   
Pathway elucidation of bioactive rhamnosylated ginsenosides in Panax ginseng and their de novo high-level production by engineered Saccharomyces cerevisiae
Authors: Chaojing Li, Xing Yan, Zhenzhen Xu, Yan Wang, Xiao Shen, Lei Zhang, Zhihua Zhou, Pingping Wang
Journal: Commun Biol
PubMed ID: 35918414
Doi: 10.1038/s42003-022-03740-y
Products & Services: Codon Optimization   
Identification of the extracellular metallo-endopeptidases ADAM and ADAMTS in the yellow fever mosquito Aedes aegypti
Authors: Christie S Herd, Xiudao Yu, Yingjun Cui, Alexander W E Franz
Journal: Insect Biochem Mol Biol
PubMed ID: 35932972
Doi: 10.1016/j.ibmb.2022.103815
Products & Services: Polyclonal Antibody Services   

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