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Engineered CRISPR prime editors with compact, untethered reverse transcriptases
Authors: Julian Grünewald, Bret R Miller, Regan N Szalay, Peter K Cabeceiras, Christopher J Woodilla, Eliza Jane B Holtz, Karl Petri, J Keith Joung
Journal: Nat Biotechnol
PubMed ID: 36163548
Doi: 10.1038/s41587-022-01473-1
Products & Services: Plasmid DNA Preparation   
Fibrotic immune microenvironment remodeling mediates superior anti-tumor efficacy of a nano-PD-L1 trap in hepatocellular carcinoma
Authors: Xiaoyu Liu, Jingying Zhou, Haoran Wu, Shufen Chen, Lingyun Zhang, Wenshu Tang, Liang Duan, Ying Wang, Eleanor McCabe, Mengying Hu, Zhuo Yu, Hanzhuang Liu, Chung Hang Jonathan Choi, Joseph Jao-Yiu Sung, Leaf Huang, Rihe Liu, Alfred Sze-Lok Cheng
Journal: Mol Ther
PubMed ID: 36146933
Doi: 10.1016/j.ymthe.2022.09.012
Products & Services: Proteins, Expression, Isolation and Analysis   
Delivery of ceramide phosphoethanolamine lipids to the cleavage furrow through the endocytic pathway is essential for male meiotic cytokinesis
Authors: Govind Kunduri, Si-Hung Le, Valentina Baena, Nagampalli Vijaykrishna, Adam Harned, Kunio Nagashima, Daniel Blankenberg, Izumi Yoshihiro, Kedar Narayan, Takeshi Bamba, Usha Acharya, Jairaj K Acharya
Journal: PLoS Biol
PubMed ID: 36170207
Doi: 10.1371/journal.pbio.3001599
Products & Services: Custom Vector Construction   
Lipidomic Analysis of Arabidopsis T-DNA Insertion Lines Leads to Identification and Characterization of C-Terminal Alterations in FATTY ACID DESATURASE 6
Authors: Hannah J Lusk, Nicholas Neumann, Madeline Colter, Mary R Roth, Pamela Tamura, Libin Yao, Sunitha Shiva, Jyoti Shah, Kathrin Schrick, Timothy P Durrett, Ruth Welti
Journal: Plant Cell Physiol
PubMed ID: 35726963
Doi: 10.1093/pcp/pcac088
Products & Services: Plasmid DNA Preparation   
Variant-specific changes in RAC3 function disrupt corticogenesis in neurodevelopmental phenotypes
Authors: Marcello Scala, Masashi Nishikawa, Hidenori Ito, Hidenori Tabata, Tayyaba Khan, Andrea Accogli, Laura Davids, Anna Ruiz, Pietro Chiurazzi, Gabriella Cericola, Björn Schulte, Kristin G Monaghan, Amber Begtrup, Annalaura Torella, Michele Pinelli, Anne Sophie Denommé-Pichon, Antonio Vitobello, Caroline Racine, Maria Margherita Mancardi, Courtney Kiss, Andrea Guerin, Wendy Wu, Elisabeth Gabau Vila, Bryan C Mak, Julian A Martinez-Agosto, Michael B Gorin, Bugrahan Duz, Yavuz Bayram, Claudia M B Carvalho, Jaime E Vengoechea, David Chitayat, Tiong Yang Tan, Bert Callewaert, Bernd Kruse, Lynne M Bird, Laurence Faivre, Marcella Zollino, Saskia Biskup, Pasquale Striano, Vincenzo Nigro, Mariasavina Severino, Valeria Capra, Gregory Costain, Koh Ichi Nagata
Journal: Brain
PubMed ID: 35851598
Doi: 10.1093/brain/awac106
Products & Services: Custom Vector Construction   
Frequency dependent growth of bacteria in living materials
Authors: Daniel D Lewis, Ting Gong, Yuanwei Xu, Cheemeng Tan
Journal: Front Bioeng Biotechnol
PubMed ID: 36159663
Doi: 10.3389/fbioe.2022.948483
Products & Services: Gene Synthesis   
Molecular fate-mapping of serum antibodies reveals the effects of antigenic imprinting on repeated immunization
Authors: Ariën Schiepers, Marije F L van 't Wout, Allison J Greaney, Trinity Zang, Hiromi Muramatsu, Paulo J C Lin, Ying K Tam, Luka Mesin, Tyler N Starr, Paul D Bieniasz, Norbert Pardi, Jesse D Bloom, Gabriel D Victora
Journal: biorxiv
PubMed ID: 36093344
Doi: 10.1101/2022.08.29.505743
Products & Services: Plasmid DNA Preparation   
Exploring the Binding Affinity and Mechanism between ACE2 and the Trimers of Delta and Omicron Spike Proteins by Molecular Dynamics Simulation and Bioassay
Authors: Liping Zhou, Tingting Liu, Mengxia Mo, Yulong Shi, Leyun Wu, Yishui Li, Qiuping Qin, Weiliang Zhu, Chengkun Wu, Likun Gong, Zhijian Xu
Journal: J Chem Inf Model
PubMed ID: 36053674
Doi: 10.1021/acs.jcim.2c00881
Products & Services: Proteins, Expression, Isolation and Analysis   
A Secreted Form of the Hepatitis E Virus ORF2 Protein: Design Strategy, Antigenicity and Immunogenicity
Authors: Zihao Chen, Shaoqi Guo, Guanghui Li, Dong Ying, Guiping Wen, Mujin Fang, Yingbin Wang, Zimin Tang, Zizheng Zheng, Ningshao Xia
Journal: Viruses
PubMed ID: 36298677
Doi: 10.3390/v14102122
Products & Services: ORF cDNA Clones/MolecularCloud   
A LILRB1 variant with a decreased ability to phosphorylate SHP-1 leads to autoimmune diseases
Authors: Thivaratana Sinthuwiwat, Supranee Buranapraditkun, Wuttichart Kamolvisit, Siraprapa Tongkobpetch, Wanna Chetruengchai, Chalurmpon Srichomthong, Adjima Assawapitaksakul, Chureerat Phokaew, Patipark Kueanjinda, Tanapat Palaga, Tadech Boonpiyathad, Kanya Suphapeetiporn, Nattiya Hirankarn, Vorasuk Shotelersuk
Journal: Sci Rep
PubMed ID: 36104364
Doi: 10.1038/s41598-022-19334-x
Products & Services: Mutagenesis Services   

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