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Acute GARP Depletion Disrupts Vesicle Transport, Leading to Severe Defects in Sorting, Secretion and O-Glycosylation

Authors: Amrita Khakurel , Irina Pokrovskaya , Vladimir V Lupashin

Journal: Traffic

PubMed ID: 39416116

Doi: 10.1111/tra.70003

Products & Services: Protein and Antibody Isolation Gene Synthesis

Molecular Modeling and In Vitro Functional Analysis of the RGS12 PDZ Domain Variant Associated with High-Penetrance Familial Bipolar Disorder

Authors: Percy S Agogo-Mawuli, Joseph Mendez, Emily A Oestreich, Dustin E Bosch, David P Siderovski

Journal: International Journal of Molecular Sciences

PubMed ID: 39518985

Doi: 10.3390/ijms252111431

Products & Services: Peptide Synthesis Bacterial Expression

Target-based design of praziquantel analogs at cestode TRPM PZQ

Authors: Daniel J. Sprague; Sang-Kyu Park; Marc Kaethner; Claudia M. Rohr; Mina R. Ghobrial; D. Connor Barth; David Maillard; Thomas Spangenberg; Britta Lundstr m-Stadelmann; Jonathan S. Marchant

Journal: ACS Infectious Diseases

PubMed ID: 40754814

Doi: 10.1021/acsinfecdis.5c00449

Enhanced HIV SOSIP Envelope yields in plants through transient co-expression of peptidyl-prolyl isomerase B and calreticulin chaperones and ER targeting

Authors: Yvonne J. Rosenberg; Xiaoming Jiang; Jonathan P. Lees; Lori A. Urban; Lingjun Mao; Markus Sack

Journal: Scientific REPORTS

PubMed ID: 35705669

Doi: 10.1038/s41598-022-14075-3

Products & Services: Catalog Antibodies

Structure of Plasmodium vivax N -myristoyltransferase with inhibitor IMP-1088: exploring an NMT inhibitor for antimalarial therapy

Authors: Alex Mendez; Cydni Bolling; Shane Taylor; Stanley Makumire; Bart Staker; Alexandra Reers; Brad Hammerson; Stephen J. Mayclin; Jan Abendroth; Donald D. Lorimer; Thomas E. Edwards; Edward W. Tate; Sandhya Subramanian; Andrew S. Bell; Peter J. Myler; Oluwatoyin A. Asojo; Graham Chakafana

Journal: Acta Crystallographica Section F: Structural Biology Communications

PubMed ID: 39655507

Doi: 10.1107/S2053230X24011348

A novel strategy of co-expressing CXCR5 and IL-7 enhances CAR-T cell effectiveness in osteosarcoma

Authors: Xinhui Hui1†Muhammad Asad Farooq,&#x;Muhammad Asad Farooq1,2†Yiran ChenYiran Chen1Iqra Ajmal,Iqra Ajmal1,2Yaojun Ren,Yaojun Ren1,3Min XueMin Xue1Yuzhou JiYuzhou Ji1Bingtan DuBingtan Du1Shijia WuShijia Wu1Wenzheng Jiang*&#x;Wenzheng Jiang1*‡

Journal: Frontiers in Immunology

Doi: doi.org/10.3389/fimmu.2024.1462076

Products & Services: Nucleic Acid Purification

AtPRMT3-RPS2B promotes ribosome biogenesis and coordinates growth and cold adaptation trade-off

Authors: Zhen Wang , Xiaofan Zhang , Chunyan Liu , Susan Duncan , Runlai Hang , Jing Sun , Lilan Luo , Yiliang Ding , Xiaofeng Cao

Journal: Nature Communications

PubMed ID: 39375381

Doi: 10.1038/s41467-024-52945-8

Products & Services: Protein and Antibody Isolation

Controlled TPCA-1 delivery engineers a pro-tenogenic niche to initiate tendon regeneration by targeting IKKβ/NF-κB signaling

Authors: Jialin Chen , Renwang Sheng , Qingyun Mo , Ludvig J Backman , Zhiyuan Lu , Qiuzi Long , Zhixuan Chen , Zhicheng Cao , Yanan Zhang , Chuanquan Liu , Haotian Zheng , Yu Qi , Mumin Cao , Yunfeng Rui , Wei Zhang

Journal: Bioact Mater

PubMed ID: 39512422

Doi: 10.1016/j.bioactmat.2024.10.016

Products & Services: Recombinant Proteins

Bitter taste receptor TAS2R14 activation and G protein assembly by an intracellular agonist

Authors: Lele Tao , Dongxue Wang , Qingning Yuan Fenghui Zhao , Yu Zhang , Tianyuan Du , Shiyi Shen , H Eric Xu , Yi Li , Dehua Yang , Jia Duan

Journal: Cell Research

PubMed ID: 38969802

Doi: 10.1038/s41422-024-00995-4

Products & Services: Catalog Peptides

Retrograde transport of neurotrophin receptor TrkB-FL induced by excitotoxicity regulates Golgi stability and is a target for stroke neuroprotection

Authors: Gema María Esteban-Ortega, Margarita Díaz-Guerra

Journal: biorxiv

Doi: doi.org/10.1101/2024.10.29.620835

Products & Services: Peptide Synthesis Protein and Antibody Isolation