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页码: 167/5364 每页显示数量

Structural Insights into the High Basal Activity and Inverse Agonism of the Orphan GPR6 Receptor Implicated in Parkinson s Disease

Authors: Mahta Barekatain; Linda C. Johansson; Jordy H. Lam; Hao Chang; Anastasiia V. Sadybekov; Gye Won Han; Joseph Russo; Joshua Bliesath; Nicola Brice; Mark B. L. Carlton; Kumar S. Saikatendu; Hukai Sun; Sean T. Murphy; Holger Monenschein; Hans H. Schiffer; Petr Popov; Corinne A. Lutomski; Carol V. Robinson; Zhi-Jie Liu; Tian Hua; Vsevolod Katritch; Vadim Cherezov

Journal: Science Signaling

PubMed ID: 39626010

Doi: 10.1126/scisignal.ado8741

Beyond the MEP Pathway: A novel kinase required for prenol utilization by malaria parasites

Authors: Marcell Crispim; Ignasi Bofill Verdaguer; Agust n Hern ndez; Thales Kronenberger; ngel Fenollar; Lydia Fumiko Yamaguchi; Mar a P a Alberione; Miriam Ramirez; Sandra Souza de Oliveira; Alejandro Miguel Katzin; Luis Izquierdo; Kirk W. Deitsch; James J Collins III; Kirk W. Deitsch; James J Collins III; Kirk W. Deitsch; James J Collins III; Kirk W. Deitsch; James J Collins III

Journal: PLOS Pathogens

PubMed ID: 38277417

Doi: 10.1371/journal.ppat.1011557

Products & Services: PCR Cloning and Subcloning

Omicron-specific ultra-potent SARS-CoV-2 neutralizing antibodies targeting the N1 N2 loop of Spike N-terminal domain

Authors: Xiao Niu, Zhiqiang Li, Jing Wang, Fanchong Jian, Yuanling Yu, Weiliang Song, Ayijiang Yisimayi, Shuo Du, Zhiying Zhang, Qianran Wang, Ran An, Yao Wang, Peng Wang, Haiyan Sun, Lingling Yu, Sijie Yang, Tianhe Xiao, Qingqing Gu, Fei Shao, Youchun Wang, Junyu Xiao, Yunlong Cao

Journal: Emerg Microbes Infec.

PubMed ID: 39361729

Doi: 10.1080/22221751.2024.2412990

Products & Services: Gene Synthesis Codon Optimization

Exploring bifunctional molecules for anti-SARS-CoV-2 and anti-inflammatory activity through structure-based virtual screening, SAR investigation, and biological evaluation

Authors: Jiani Lu , Yingying He , Yaqi Li , Xixiang Chen , Hongtao Li , Xuwen Chen , Jianrong Xu , Hongzhuan Chen ，Ying Wang , Xiao He , Shunying Liu , Lili Chen

Journal: Int J Biol Macromol

PubMed ID: 39653224

Doi: 10.1016/j.ijbiomac.2024.138529

Products & Services: Peptide Synthesis

Mechanistic study of SCOOPs recognition by MIK2–BAK1 complex reveals the role of N-glycans in plant ligand–receptor– coreceptor complex formation

Authors: Huimin Wu , Lihao Wan , Zunyong Liu , Yunqing Jian , Chenchen Zhang , Xiakun Mao , Zhiyun Wang , Qiang Wang , Yaxin Hu , Lizhong Xiong , Zhujun Xia , Juan Xue , Shan Li , Ping He , Libo Shan , Shutong Xu

Journal: Nat Plants

PubMed ID: 39511418

Doi: 10.1038/s41477-024-01836-3

Products & Services: Peptide Synthesis

Immunoaffinity Intact Top-Down Mass Spectrometry for Quantification of Neuron-Specific Enolase Gamma, a Low-Abundance Protein Biomarker

Authors: Sebastian A H van den Wildenberg , Sylvia A A M Genet , Maarten A C Broeren , Joost L J van Dongen , Maxime C M van den Oetelaar , Luc Brunsveld , Volkher Scharnhorst , Daan van de Kerkhof

Journal: Anal Chem

PubMed ID: 39710932

Doi: 10.1021/acs.analchem.4c04677

Products & Services: Custom Vector Construction

Utilization of Fc-specific peptide to orientally immobilize antibodies markedly improves the analytical performance of lateral flow immunoassay strips for aflatoxin B1

Authors: Jin Li , Xintong Li , Yulian Wang , Qianxu Zhou , Guoqing Shi

Journal: Microchemical Journal

Doi: 10.1016/j.microc.2024.112404

Products & Services: Peptide Synthesis

Mycobacterium tuberculosis FasR senses long fatty acyl-CoA through a tunnel and a hydrophobic transmission spine

Authors: Julia Lara; Lautaro Diacovich; Felipe Trajtenberg; Nicole Larrieux; Emilio L. Malchiodi; Marisa M. Fern ndez; Gabriela Gago; Hugo Gramajo; Alejandro Buschiazzo

Journal: Nature Communications

PubMed ID: 32710080

Doi: 10.1038/s41467-020-17504-x

Products & Services: Recombinant Proteins

Mycobacterium tuberculosis FasR senses long fatty acyl-CoA through a tunnel and a hydrophobic transmission spine

Authors: Julia Lara; Lautaro Diacovich; Felipe Trajtenberg; Nicole Larrieux; Emilio L. Malchiodi; Marisa M. Fern ndez; Gabriela Gago; Hugo Gramajo; Alejandro Buschiazzo

Journal: Nature Communications

PubMed ID: 32710080

Doi: 10.1038/s41467-020-17504-x

Products & Services: Recombinant Proteins

Mycobacterium tuberculosis FasR senses long fatty acyl-CoA through a tunnel and a hydrophobic transmission spine

Authors: Julia Lara; Lautaro Diacovich; Felipe Trajtenberg; Nicole Larrieux; Emilio L. Malchiodi; Marisa M. Fern ndez; Gabriela Gago; Hugo Gramajo; Alejandro Buschiazzo

Journal: Nature Communications

PubMed ID: 32710080

Doi: 10.1038/s41467-020-17504-x

Products & Services: Recombinant Proteins