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Structural insights into polymerase-catalyzed FAD capping of hepatitis C virus RNA

Authors: De-Ping Wang, Rong Zhao, Wen-Shu Hu, Hai-Ning Li, Ji-Min Cao, Xin Zhou, Ye Xiang

Journal: Nature Communications

PubMed ID: 40775214

Doi: 10.1038/s41467-025-62609-w.

Products & Services: Protein and Antibody Isolation

Polycystin-1 Mutant Alters Mechanotransduction in Response to Collagen and Extracellular Matrix Stiffness via Daam1-Dependent Microfilament Remodeling

Authors: Jiaofeng Zhou, Yibing Deng, Jie Mei, Mengyun Wan, Ningyi Xue, Xinyu Zong, Ji Zhou, Junli Ding, Ting Yan, Yu Jiang, Tiansong Xia, Peng Zheng, Yichao Zhu

Journal: Advanced Science

PubMed ID: 40789101

Doi: 10.1002/advs.202509846

Products & Services: Mutagenesis Services

Soluble N-terminal region of prion protein causes rapid neurodegeneration in prion disease

Authors: Runchuan Yan, Yan Zhang, Jingjing Zhang, Xiangyi Zhang, Yue Han, Mengfei Wang, Dan Wang, Shengnan Huang, Wei Liu, Qi Shi, Xiaoping Dong, Wen-Quan Zou, Zhen Li, Jiyan Ma

Journal: SCIENCE ADVANCES

PubMed ID: 40768577

Doi: 10.1126/sciadv.adw6867

Products & Services: Recombinant Antibody Expression

Irreversible furin cleavage site exposure renders immature tick-borne flaviviruses fully infectious

Authors: Jiří Holoubek, Jiří Salát, Milos Matkovic, Petr Bednář, Pavel Novotný, Martin Hradilek, Taťána Majerová, Ebba Rosendal, Luděk Eyer, Andrea Fořtová, Michaela Beránková, Lesley Bell-Sakyi, Anna K. Överby, Andrea Cavalli, Massimiliano Bonomi, Félix A. Rey, Daniel Růžek

Journal: Nature Communications

PubMed ID: 40796726

Doi: 10.1038/s41467-025-62750-6.

Products & Services: PCR Cloning and Subcloning

Quantifying collective interactions in biomolecular phase separation

Authors: Hannes Ausserwöger, Ella de Csilléry, Daoyuan Qian, Georg Krainer, Timothy J Welsh, Tomas Sneideris, Titus M Franzmann, Seema Qamar, Nadia A Erkamp, Jonathon Nixon-Abell, Mrityunjoy Kar, Peter St George-Hyslop, Anthony A Hyman, Simon Alberti, Rohit V Pappu, Tuomas P J Knowles

Journal: Nature Communications

PubMed ID: 40830100

Doi: 10.1038/s41467-025-62437-y.

Mesothelin-directed protein-drug conjugates for mesothelin-low solid tumor therapy

Authors: Ying Wang, Jiayao Yan, Lin Li, Tianran Chen, Jingyi Guo, Lei Lei, Siwen Wu, Lijing Zhu, Xiaotong Chen, Baorui Liu

Journal: Nature Communications

PubMed ID: 40849430

Doi: 10.1038/s41467-025-63269-6.

Products & Services: Recombinant Proteins

The cAMP-PKA signaling initiates mitosis by phosphorylating Bora

Authors: Min Zhu, Shinan Zhou, Yingqi Zhang, Qinfu Chen, Xueying Yuan, Long Zhang, Haiyan Yan, Fangwei Wang

Journal: Nature Communications

PubMed ID: 40849432

Doi: 10.1038/s41467-025-63352-y.

Products & Services: Polyclonal Antibody Services

Helicobacter hepaticus promotes hepatic steatosis through CdtB-induced mitochondrial stress and lipid metabolism reprogramming

Authors: Shanhao Jin, Liqi Zhu, Ruoyu Bao, Linghan Yang, Tinglong Zhuang, Liyou Lian, Tao Wang, Jun Yin, Shilei Zhang, Lei Zhou, Minghua Zheng, Quan Zhang

Journal: Nature Communications

PubMed ID: 40858606

Doi: 10.1038/s41467-025-63351-z.

Products & Services: Protein and Antibody Isolation

Genetic architecture of a light-temperature coincidence detector

Authors: Adam Seluzicki , Joanne Chory

Journal: Nature Communications

PubMed ID: 40858539

Doi: 10.1038/s41467-025-62194-y.

Products & Services: Custom Vector Construction

Senotoxins target senescence via lipid binding specificity, ion imbalance and lipidome remodeling

Authors: Javier Moral-Sanz; Isabel Fern ndez-Carrasco; Valentina Ramponi; Amanda Garrido; Izhar Karbat; Pablo Cabezas-Sainz; Esperanza Rivera-de-Torre; Osama Elsallabi; Roberto Mart n-Hern ndez; Jos L. L pez-Aceituno; Nathan L. Price; Laura Sanchez; Gonzalo Colmenarejo; lvaro Mart nez-del-Pozo; Irina Vetter; Angel Cogolludo; Francisco Perez-Vizcaino; Jorge Del-Pozo; Eitan Reuveny; Manuel A. Fern ndez-Rojo; Paul D. Robbins; Rafael de Cabo; Manuel Serrano; Maria P. Ikonomopoulou

Journal: Nature Aging

PubMed ID: 41526742

Doi: 10.1038/s43587-025-01030-w

Products & Services: PCR Cloning and Subcloning