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IL-10-providing B cells govern pro-inflammatory activity of macrophages and microglia in CNS autoimmunity

Authors: Anastasia Geladaris, Silke Häusser-Kinzel, Roxanne Pretzsch, Nitzan Nissimov, Klaus Lehmann-Horn, Darius Häusler, Martin S Weber

Journal: Acta Neuropathol

PubMed ID: 36854993

Doi: 10.1007/s00401-023-02552-6

Products & Services: Protein and Antibody Isolation

IGFBP‑rP1 affects the proliferation, apoptosis and macrophage polarization of endometrial cancer cells by regulating the PI3K/AKT pathway

Authors: Juan Gao, Shiqi Suo, Jingxia Li, Chunxia Wang, Ranran Deng, Yuxia Hu, Chunzheng Zhang

Journal: Exp Ther Med

PubMed ID: 37006880

Doi: 10.3892/etm.2023.11868

Products & Services: Protein and Antibody Isolation

miR-126 mitigates the osteogenic differentiation of human bone marrow-derived mesenchymal stem cells by targeting the ERK1/2 and Bcl-2 pathways

Authors: Ying Zhang, Yiping Dong, Qiushi Wei, Zhikun Zhuang, Youwen Liu, Qiang Yuan, Wei He, Zhenhao Jing, Jitian Li, Peifeng Li, Leilei Zhang, Zhinan Hong, Ning Zhang, Haibin Wang, Wuyin Li

Journal: Acta Biochim Biophys Sin (Shanghai)

PubMed ID: 36942990

Doi: 10.3724/abbs.2023016

Products & Services: Protein and Antibody Isolation

The proprotein convertase SKI-1/S1P is a critical host factor for Nairobi sheep disease virus infectivity

Authors: Caroline Bost, Julia Hartlaub, Vinícius Pinho Dos Reis, Thomas Strecker, Nabil G Seidah, Martin H Groschup, Sandra Diederich, Kerstin Fischer

Journal: Virus Res

PubMed ID: 36948228

Doi: 10.1016/j.virusres.2023.199099

Products & Services: Protein and Antibody Isolation

Rare Catechol--methyltransferase Missense Variants Are Structurally Unstable Proteasome Targets

Authors: Fia B Larsen, Matteo Cagiada, Jonas Dideriksen, Amelie Stein, Kresten Lindorff-Larsen, Rasmus Hartmann-Petersen

Journal: Biochemistry

PubMed ID: 36976271

Doi: 10.1021/acs.biochem.3c00008

Products & Services: Protein and Antibody Isolation

Relative role of border restrictions, case finding and contact tracing in controlling SARS-CoV-2 in the presence of undetected transmission: a mathematical modelling study

Authors: Rachael Pung, Hannah E Clapham, Timothy W Russell, Vernon J Lee, Adam J Kucharski

Journal: BMC Med

PubMed ID: 36927576

Doi: 10.1186/s12916-023-02802-0

Products & Services: Protein and Antibody Isolation

COVID-19 vaccines based on viral nanoparticles displaying a conserved B-cell epitope show potent immunogenicity and a long-lasting antibody response

Authors: Jessica Fernanda Affonso de Oliveira; Zhongchao Zhao; Yi Xiang; Matthew D. Shin; Kathleen Elizabeth Villase or; Xinyi Deng; Sourabh Shukla; Shaochen Chen; Nicole F. Steinmetz

Journal: Frontiers in Microbiology

PubMed ID: 37152732

Doi: 10.3389/fmicb.2023.1117494

Adenosine deaminase augments SARS-CoV-2 specific cellular and humoral responses in aged mouse models of immunization and challenge

Authors: Ebony N Gary, Nicholas J Tursi, Bryce M Warner, Gina Cuismano, Jennifer Connors, Elizabeth M Parzych, Bryan D Griffin, Matthew R Bell, Ali R Ali, Drew Frase, Casey E Hojecki, Gabriela A Canziani, Irwin Chaiken, Toshitha Kannan, Estella Moffat, Carissa Embury-Hyatt, Sarah K Wooton, Andrew Kossenkov, Ami Patel, Darwyn Kobasa, Michele A Kutzler, Elias K Haddad, David B Weiner

Journal: Front Immunol

PubMed ID: 36999023

Doi: 10.3389/fimmu.2023.1138609

Products & Services: Molecular Biology Reagents

Identification of specific and shared epitopes at the extreme N-terminal VP1 of Coxsackievirus A4, A2 and A5 by monoclonal antibodies

Authors: Yu-Xuan Tian, Wei-Ping Jin, Zhen-Ni Wei, Shi-Yun Lv, Meng-Jun Wang, Sheng-Li Meng, Jing Guo, Ze-Jun Wang, Shuo Shen

Journal: Virus Res

PubMed ID: 36805409

Doi: 10.1016/j.virusres.2023.199074

Products & Services: Peptide Synthesis

PF-D-Trimer, a protective SARS-CoV-2 subunit vaccine: immunogenicity and application

Authors: Zhihao Zhang, Jinhu Zhou, Peng Ni, Bing Hu, Normand Jolicoeur, Shuang Deng, Qian Xiao, Qian He, Gai Li, Yan Xia, Mei Liu, Cong Wang, Zhizheng Fang, Nan Xia, Zhe-Rui Zhang, Bo Zhang, Kun Cai, Yan Xu, Binlei Liu

Journal: npj Vaccines

PubMed ID: 36922524

Doi: 10.1038/s41541-023-00636-8

Products & Services: Gene Synthesis