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至今，GenScript的服务及产品已被Cell, Nature, Science, PNAS等1300多家生物医药类杂志引用近万次，处于行业领先水平。NIH、哈佛、耶鲁、斯坦福、普林斯顿、杜克大学等约400家全球著名机构使用GenScript的基因合成、多肽服务、抗体服务和蛋白服务等成功地发表科研成果，再次证明GenScript 有能力帮助业内科学家Make research easy.

页码: 5/4912 每页显示数量

N-homocysteinylation of DJ-1 promotes neurodegeneration in Parkinson's disease

Authors: Tao Guo, Lingyan Zhou, Min Xiong, Jing Xiong, Juan Huang, Yiming Li, Guoxin Zhang, Guiqin Chen, Zhi-Hao Wang, Tingting Xiao, Dan Hu, Anyu Bao, Zhentao Zhang

Journal: Aging Cell

PubMed ID: 38380563

Doi: 10.1111/acel.14124

Products & Services: Proteins, Expression, Isolation and Analysis

Engineering Anti-CRISPR Proteins to Create Cas12a Protein Switches for Activatable Genome Editing and Viral Protease Detection

Authors: Wenyuan Kang, Fei Xiao, Xi Zhu, Xinyu Ling, Shiyi Xie, Ruimiao Li, Peihang Yu, Linxin Cao, Chunyang Lei, Ye Qiu, Tao Liu , Zhou Nie

Journal: Angew Chem Int Ed Engl .

PubMed ID: 38407550

Doi: 10.1002/anie.202400599

MFSD7c functions as a transporter of choline at the blood–brain barrier

Authors: Xuan Thi Anh Nguyen, Thanh Nha Uyen Le, Toan Q. Nguyen, Hoa Thi Thuy Ha, Anna Artati, Nancy C. P. Leong, Dat T. Nguyen, Pei Yen Lim, Adelia Vicanatalita Susanto, Qianhui Huang, Ling Fam, Lo Ngah Leong, Isabelle Bonne, Angela Lee, Jorge L. Granadillo, Catherine Gooch, Dejie Yu, Hua Huang, Tuck Wah Soong, Matthew Wook Chang, Markus R. Wenk, Jerzy Adamski, Amaury Cazenave-Gassiot & Long N. Nguyen

Journal: Cell Research

PubMed ID: 38302740

Doi: 10.1038/s41422-023-00923-y

Products & Services: Plasmid DNA Preparation

hRpn13 shapes the proteome and transcriptome through epigenetic factors HDAC8, PADI4, and transcription factor NF-κB p50

Authors: Vasty Osei-Amponsa, Monika Chandravanshi, Xiuxiu Lu , Valentin Magidson, Sudipto Das, Thorkell Andresson, Marzena Dyba, Venkata R Sabbasani, Rolf E Swenson, Caroline Fromont, Biraj Shrestha, Yongmei Zhao, Michelle E Clapp, Raj Chari, Kylie J Walters

Journal: Cell

PubMed ID: 38151017

Doi: 10.1016/j.molcel.2023.11.035

Products & Services: Plasmid DNA Preparation

Rapid simulation of glycoprotein structures by grafting and steric exclusion of glycan conformer libraries

Authors: Yu-Xi Tsai, Ning-En Chang, Klaus Reuter, Hao-Ting Chang, Tzu-Jing Yang, Sören von Bülow, Vidhi Sehrawat, Noémie Zerrouki, Matthieu Tuffery, Michae Gecht, Isabell Louise Grothaus, Lucio Colombi Ciacchi, Yong-Sheng Wang, Min-Feng Hsu, Kay-Hooi Khoo, Gerhard Hummer, Shang-Te Danny Hsu, Cyril Hanus , Mateusz Sikora

Journal: Cell

PubMed ID: 38428397

Doi: 10.1016/j.cell.2024.01.034

Products & Services: Gene Synthesis

Protective human monoclonal antibodies target conserved sites of vulnerability on the underside of influenza virus neuraminidase

Authors: Julia Lederhofer, Yaroslav Tsybovsky, Lam Nguyen, Julie E Raab, Adrian Creanga, Tyler Stephens, Rebecca A Gillespie, Hubza Z Syeda, Brian E Fisher, Michelle Skertic , Christina Yap, Andrew J Schaub, Reda Rawi, Peter D Kwong, Barney S Graham, Adrian B McDermott , Sarah F Andrews , Neil P King , Masaru Kanekiyo

Journal: Immunity

PubMed ID: 38430907

Doi: 10.1016/j.immuni.2024.02.003

Products & Services: Gene Synthesis

Signaling via a CD27-TRAF2-SHP-1 axis during naive T cell activation promotes memory-associated gene regulatory networks

Authors: Carla A Jaeger-Ruckstuhl Yun Lo, Elena Fulton , Olivia G Waltner, Tamer B Shabaneh , Sylvain Simon , Pranav V Muthuraman , Colin E Correnti , Oliver J Newsom , Ian A Engstrom , Sami B Kanaan , Shruti S Bhise , Jobelle M C Peralta , Raymond Ruff , Jason P Price , Sylvia M Stull , Andrew R Stevens , Grace Bugos, Mitchell G Kluesner , Valentin Voillet, Vishaka Muhunthan, Fionnuala Morrish, James M Olson , Raphaël Gottado , Jay F Sarthy, Steven Henikoff , Lucas B Sullivan, Scott N Furlan, Stanley R Riddell

Journal: Immunity

PubMed ID: 38354704

Doi: 10.1016/j.immuni.2024.01.011

Products & Services: Codon Optimization

PP2A and GSK3 act as modifiers of FUS-ALS by modulating mitochondrial transport

Authors: Paraskevi Tziortzouda , Jolien Steyaert , Wendy Scheveneels , Adria Sicart , Katarina Stoklund Dittlau , Adriana Margarida Barbosa Correia , Thibaut Burg , Arun Pal , Andreas Hermann , Philip Van Damme , Thomas G Moens , Ludo Van Den Bosch

Journal: Acta Neuropathol

PubMed ID: 38363426

Doi: 10.1007/s00401-024-02689-y

Products & Services: Peptide Synthesis

ZSCAN10 deficiency causes a neurodevelopmental disorder with characteristic oto-facial

Authors: Lucia Laugwitz, Fubo Cheng, Stephan C Collins, Alexander Hustinx, Nicolas Navarro, Simon Welsch, Helen Cox, Tzung-Chien Hsieh, Aswinkumar Vijayananth, Rebecca Buchert, Benjamin Bender, Stephanie Efthymiou, David Murphy, Faisal Zafar, Nuzhat Rana, Ute Grasshoff, Ruth J Falb, Mona Grimmel, Annette Seibt, Wenxu Zheng, Hamid Ghaedi, Marie Thirion, Sébastien Couette, Reza Azizimalamiri, Saeid Sadeghian, Hamid Galehdari, Mina Zamani, Jawaher Zeighami, Alireza Sedaghat, Samira Molaei Ramshe, Ali Zare, Behnam Alipoor, Dirk Klee,

Journal: Brain

PubMed ID: 38386308

Doi: 10.1093/brain/awae058

Products & Services: PCR Cloning and Subcloning

Local structural preferences in shaping tau amyloid polymorphism

Authors: Nikolaos Louros , Martin Wilkinson , Grigoria Tsaka , Meine Ramakers , Chiara Morelli , Teresa Garcia , Rodrigo Gallardo , Sam D'Haeyer , Vera Goossens , Dominique Audenaert , Dietmar Rudolf Thal , Ian R Mackenzie , Rosa Rademakers , Neil A Ranson , Sheena E Radford , Frederic Rousseau , Joost Schymkowitz

Journal: Nat Commun

PubMed ID: 38310108

Doi: 10.1038/s41467-024-45429-2

Products & Services: Peptide Synthesis

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