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Fused exosomal targeted therapy in periprosthetic osteolysis through regulation of bone metabolic homeostasis
Authors: Tianliang Ma, Qimeng Liu, Zheyu Zhang, Jiangyu Nan, Guanzhi Liu, Yute Yang, Yihe Hu, Jie Xie
Journal: Bioactive Materials
PubMed ID: 40248188
Doi: doi.org/10.1016/j.bioactmat.2025.04.006
Identification of RC3H1 as antiviral host factor binding to the non-structural protein 1 of Influenza A virus via a 3-stage computational pipeline and cell-based analysis
Authors: Swee Teng Teo , Shamima Rashid , Kong Yen Liew , Kah Man Lai , Teng Ann Ng , Jifeng Jiao , Chee Keong Kwoh , Yee-Joo Tan
Journal: Virology Journal
PubMed ID: 40287742
Doi: 10.1186/s12985-025-02746-2
Products & Services: ORF cDNA Clones/MolecularCloud   
N-Terminal random curl-tandam α-helical peptide 7W: A potent antibacterial and anti-inflammatory dual-effect agent through tryptophan substitution
Authors: Jietao Lou, Xinyi Wu, Wenwen Ji, Jiaye Yu, Yanyan Xu, Wanyang Xiao, Weijie Lu, Kaiyun Xin, Tianbao Chen, Qidong Tang, Guang Liang, Yitian Gao, Di Wu
Journal: Eur J Med Chem
PubMed ID: 40319576
Doi: 10.1016/j.ejmech.2025.117686
Products & Services: Peptide Synthesis   
Phosphorylation dependent charge block regulate the relaxation of nuclear speckle networks
Authors: Mengjun Zhang, Zhuang Gu, Yingtian Sun, Yichen Dong, Junlin Chen, Li Shu, Suibin Ma, Jierui Guo, Yuhang Liang, Qingming Qu, Ning Fang, Chuan-Qi Zhong, Yifan Ge, Zhongwen Chen, Shaohui Huang, Xin Zhang, Bo Wang
Journal: Mol Cell
PubMed ID: 40233760
Doi: 10.1016/j.molcel.2025.03.016
Targeted Delivery of mRNA with Polymer−Lipid Nanoparticles for In Vivo Base Editing
Authors: Qimingxing Chen, Yan Chang, Xiaoyan He, Yan Ding, Runyuan Wang, Ran Luo, Jialu Yuan, Jiabei Chen, Guisheng Zhong, Huiying Yang, Jia Chen, Jianfeng Li
Journal: ACS Nano
PubMed ID: 39962883
Doi: 10.1021/acsnano.4c14041
Fullerol Initiates Stem Cell–Nanomaterials Interactions for Enhanced Tissue Regeneration via Clathrin-Mediated Endocytosis and Nuclear Factor Erythroid 2-Related Factor 2 Signaling
Authors: Haoyang Liu, Yue Zhu, Weixu Chen, Renwang Sheng, Chuanquan Liu, Yuzhi Sun, Jia Liu, Mingyue Wang, Jun Lu, Jialin Chen, Wei Zhang
Journal: ACS Applied Materials & Interfaces
Doi: 10.1021/acsami.5c01731
Products & Services: Recombinant Proteins   
PIN1-SUMO2/3 motif suppresses excessive RNF168 chromatin accumulation and ubiquitin signaling to promote IR resistance
Authors: Anoop S Chauhan, Matthew J W Mackintosh, Joseph Cassar, Alexander J Lanz, Mohammed Jamshad, Hannah L Mackay, Alexander J Garvin, Alexandra K Walker, Satpal S Jhujh, Teresa Carlomagno, Aneika C Leney, Grant S Stewart, Joanna R Morris
Journal: Nature Communication
PubMed ID: 40229270
Doi: 10.1038/s41467-025-56974-9
Products & Services: Peptide Synthesis   Monoclonal Antibody Services   
Metabolite-dependent m6A methylation driven by mechanotransduction-metabolism-epitranscriptomics axis promotes bone development and regeneration
Authors: Zhuo Li, Zhengnan Guo, Zhengmeng Yang, Boguang Yang, Yuan Hu, Xian Xie, Zhixian Zong, Zekun Chen, Kunyu Zhang, Pengchao Zhao, Gang Li, Xuefeng Yang, Liming Bian
Journal: Cell Rep
PubMed ID: 40272981
Doi: 10.1016/j.celrep.2025.115611
Products & Services: Peptide Synthesis   
Inhibiting Chemotherapy Immune Tolerance and Reversing Tumor Microenvironment by Macrophage-Targeted Nanohybrid Systems for Enhancing Tumor Chemo-Immunotherapy
Authors: You-Teng Qin, Zhi-Yong Rao, Jia-Xin An, Shi-Man Zhang, Yu-Zhang Wang, Ting Pan, and Xian-Zheng Zhang
Journal: Advanced Functional Materials
Doi: doi.org/10.1002/adfm.202501954
Products & Services: Recombinant Proteins   
Molecular mechanisms of urate transport by the native human URAT1 and its inhibition by anti-gout drugs
Authors: Canrong Wu, Chao Zhang, Sanshan Jin, James Jiqi Wang, Antao Dai, Jiuyin Xu, Heng Zhang, Xuemei Yang, Xinheng He, Qingning Yuan, Wen Hu, Youwei Xu, Mingwei Wang, Yi Jiang, Dehua Yang, H Eric Xu
Journal: Cell Discov
PubMed ID: 11962085
Doi: 10.1038/s41421-025-00779-z
Products & Services: Catalog Peptides   

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