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Broad protection against clade 1 sarbecoviruses after a single immunization with cocktail spike-protein-nanoparticle vaccine

Authors: Peter J. Halfmann; Kathryn Loeffler; Augustine Duffy; Makoto Kuroda; Jie E. Yang; Elizabeth R. Wright; Yoshihiro Kawaoka; Ravi S. Kane

Journal: Nature Communications

PubMed ID: 38346966

Doi: 10.1038/s41467-024-45495-6

Products & Services: PCR Cloning and Subcloning

Development of chimeric protein as a multivalent vaccine for human Kinetoplastid infections: Chagas disease and leishmaniasis

Authors: Marianna de Carvalho Clímaco, Luiza Almeida de Figueiredo, Rayane Cristina Lucas, Guilherme Rafael Gomide Pinheiro, Luísa Mourão Dias Magalhães, Ana Laura Grossi de Oliveira, Raquel Martins Almeida, Fernando Sérgio Barbosa, Daniella Castanheira Bartholomeu, Lilian Lacerda Bueno, Tiago Antonio Mendes, Bin Zhan, Kathryn Marie Jones, Peter Hotez, Maria Elena Bottazzi, Fabrício Marcus Silva Oliveira, Ricardo Toshio Fujiwara

Journal: Vaccine

PubMed ID: 37479612

Doi: 10.1016/j.vaccine.2023.07.020

Products & Services: Gene Synthesis

Integrated analysis and validation of TRIM23/p53 signaling pathway in hepatic stellate cells ferroptosis and liver fibrosis

Authors: Jie Chen, Rui Zhang, Feng Li, Shengli Lin, Jian Wang

Journal: Dig Liver Dis

PubMed ID: 37495427

Doi: 10.1016/j.dld.2023.07.010

Products & Services: Molecular Biology Reagents

Structure-based design of SARS-CoV-2 papain-like protease inhibitors

Authors: Prakash Jadhav; Bo Huang; Jerzy Osipiuk; Xiaoming Zhang; Haozhou Tan; Christine Tesar; Michael Endres; Robert Jedrzejczak; Bin Tan; Xufang Deng; Andrzej Joachimiak; Jianfeng Cai; Jun Wang

Journal: European Journal of Medicinal Chemistry

PubMed ID: 38065031

Doi: 10.1016/j.ejmech.2023.116011

Structure-based design of SARS-CoV-2 papain-like protease inhibitors

Authors: Prakash Jadhav; Bo Huang; Jerzy Osipiuk; Xiaoming Zhang; Haozhou Tan; Christine Tesar; Michael Endres; Robert Jedrzejczak; Bin Tan; Xufang Deng; Andrzej Joachimiak; Jianfeng Cai; Jun Wang

Journal: European Journal of Medicinal Chemistry

PubMed ID: 38065031

Doi: 10.1016/j.ejmech.2023.116011

Targeting the Spike Receptor Binding Domain Class V Cryptic Epitope by an Antibody with Pan-Sarbecovirus Activity

Authors: Jaime L Jensen, Rajeshwer S Sankhala, Vincent Dussupt, Hongjun Bai, Agnes Hajduczki, Kerri G Lal, William C Chang, Elizabeth J Martinez, Caroline E Peterson, Emily S Golub, Phyllis A Rees, Letzibeth Mendez-Rivera, Michelle Zemil, Erin Kavusak, Sandra V Mayer, Lindsay Wieczorek, Shruthi Kannan, Benjamin J Doranz, Edgar Davidson, Eun Sung Yang, Yi Zhang, Man Chen, Misook Choe, Lingshu Wang, Gregory D Gromowski, Richard A Koup, Nelson L Michael, Victoria R Polonis, Morgane Rolland, Kayvon Modjarrad, Shelly J Krebs, M Gordon Joyce

Journal: J Virol

PubMed ID: 37395646

Doi: 10.1128/jvi.01596-22

Products & Services: Gene Synthesis

A natural gene drive system confers reproductive isolation in rice

Authors: Chaolong Wang, Jian Wang, Jiayu Lu, Yehui Xiong, Zhigang Zhao, Xiaowen Yu, Xiaoming Zheng, Jing Li, Qibing Lin, Yulong Ren, Yang Hu, Xiaodong He, Chao Li, Yonglun Zeng, Rong Miao, Mali Guo, Bosen Zhang, Ying Zhu, Yunhui Zhang, Weijie Tang, Yunlong Wang, Benyuan Hao, Qiming Wang, Siqi Cheng, Xiaojuan He, Bowen Yao, Junwen Gao, Xufei Zhu, Hao Yu, Yong Wang, Yan Sun, Chunlei Zhou, Hui Dong, Xiaoding Ma, Xiuping Guo, Xi Liu, Yunlu Tian, Shijia Liu, Chunming Wang, Zhijun Cheng, Ling Jiang, Jiawu Zhou, Huishan Guo, Liwen Jiang, Dayun Tao, Jijie Chai, Wei Zhang, Haiyang Wang, Chuanyin Wu, Jianmin Wan

Journal: Cell

PubMed ID: 37499659

Doi: 10.1016/j.cell.2023.06.023

Products & Services: Protein and Antibody Isolation

A mass spectrometry assay for detection of endogenous and lentiviral engineered hemoglobin in cultured cells and sickle cell disease mice

Authors: Xuejun Wang, William M McKillop, Theresa A Dlugi, Mary L Faber, Juliana Alvarez-Argote, Christopher B Chambers, Andrew Wilber, Jeffrey A Medin

Journal: J Gene Med

PubMed ID: 37455676

Doi: 10.1002/jgm.3567

Products & Services: Peptide Synthesis

Accurate identification and discrimination of serovar Gallinarum biovars Gallinarum and Pullorum by a multiplex PCR based on the new genes of and

Authors: Li Song, Ruimeng Tan, Dan Xiong, Xinan Jiao, Zhiming Pan

Journal: Front Vet Sci

PubMed ID: 37476820

Doi: 10.3389/fvets.2023.1220118

Products & Services: Protein and Antibody Isolation

Actions of a Novel Bacterial Topoisomerase Inhibitor against Gyrase and Topoisomerase IV: Enhancement of Double-Stranded DNA Breaks

Authors: Soziema E Dauda, Jessica A Collins, Jo Ann W Byl, Yanran Lu, Jack C Yalowich, Mark J Mitton-Fry, Neil Osheroff